All Outputs (228)

Building oscillations bottom up: Elemental time scales of intracellular calcium dynamics (2007)
Book Chapter

We analyze the elemental time scale of intracellular calcium dynamics. It is determined by the time course of Ca2+ puffs, which represent the fundamental quantum of Ca2+ release from intracellular storage compartments. Since Ca2+ puffs are truly rand... Read More about Building oscillations bottom up: Elemental time scales of intracellular calcium dynamics.

Enabling rapid and cost-effective creation of massive pervasive games in very unstable environments (2007)
Conference Proceeding

Pervasive gaming is a new form of multimedia entertainment that extends the traditional computer gaming experience out into the real world. Through a combination of personal devices, positioning systems and other sensors, combined with wireless netwo... Read More about Enabling rapid and cost-effective creation of massive pervasive games in very unstable environments.

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg (2007)
Journal Article

Background: This paper describes the results of a feasibility study for a randomised controlled trial (RCT). Methods: Twenty-nine members of the UK Dermatology Clinical Trials Network (UK DCTN) expressed an interest in recruiting for this study.... Read More about Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg.

Blanching the airways: steroid effects in asthma (2007)
Journal Article

Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters (2007)
Journal Article

Thyrotrophin-releasing hormone (TRH) is known to play an important role in the control of food intake and energy metabolism in addition to its actions on the pituitary-thyroid axis. We have previously shown that central administration of TRH decrease... Read More about Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters.

The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses (2007)
Journal Article

Background: The cysteine protease Der p 1 from the house dust mite Dermatophagoides pteronyssinus is one of the most potent allergens known. An attractive mechanism for a component of Der p 1 allergenicity lies in its ability to cleave key regulatory... Read More about The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: Experimental analysis of in silico substrate identification and implications in allergic responses.

Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district (2007)
Journal Article

This paper argues that the conflicts of interest cases brought against Wall Street investment banks in the early 2000s were neither geographically nor institutionally isolated events. Rather, by combining recent work on financial knowledges in both e... Read More about Knowledge makes the money go round: Conflicts of interest and corporate finance in London's financial district.

Cross-Species Identification of Mendel's I Locus (2007)
Journal Article

A key gene involved in plant senescence, mutations of which partially disable chlorophyll catabolism and confer stay-green leaf and cotyledon phenotypes, has been identified in Pisum sativum, Arabidopsis thaliana, and Festuca pratensis by using class... Read More about Cross-Species Identification of Mendel's I Locus.

Oscillons and quasi-breathers in D+1 dimensions (2007)
Journal Article

We study oscillons in D+1 space-time dimensions using a spherically symmetric ansatz. From Gaussian initial conditions, these evolve by emitting radiation, approaching ``quasi-breathers'', near-periodic solutions to the equations of motion. Using a t... Read More about Oscillons and quasi-breathers in D+1 dimensions.

Depression and mood changes (2007)
Book Chapter

Depression is the most common mental health problem experienced by older women. Although everyone may feel sad or lonely at times, depressive illness in later life is qualitatively and quantitatively different. True depression is a serious and disabl... Read More about Depression and mood changes.

Foster Fathers: their experiences and contributions to fostering (2007)
Journal Article

The paper reports some of the findings of an exploratory study which looks at foster fathers’ experiences of fostering and discusses their routes into foster care and their perspectives on their roles and tasks. The study collected quantitative and q... Read More about Foster Fathers: their experiences and contributions to fostering.

Risk, human rights and the management of a serious sex offender (2007)
Journal Article

Risk and human rights discourses have become dominant features of the UK criminal justice arena. However, there has been little critical scrutiny of the ways in which these discourses relate to each other. In this article, I focus on different accoun... Read More about Risk, human rights and the management of a serious sex offender.

Robust recognition of planar shapes under affine transforms using principal component analysis (2007)
Journal Article

A scheme, based on Principal Component Analysis (PCA), is proposed that can be used for the recognition of 2D planar shapes under affine transformations. A PCA step is first used to map the object boundary to its canonical form, reducing the problem... Read More about Robust recognition of planar shapes under affine transforms using principal component analysis.

An affine invariant function using PCA bases with an application to within-class object recognition (2007)
Conference Proceeding

The problem of shape-based recognition of objects under affine transformations is considered. We focus on the construction of a robust and highly discriminative affine invariant function that can be used for within-class object recognition applicatio... Read More about An affine invariant function using PCA bases with an application to within-class object recognition.

Calcium oscillations (2007)
Book Chapter

Changes in cellular calcium concentration control a wide range of physiological processes, from the subsecond release of synaptic neurotransmitters, to the regulation of gene expression over months or years. Calcium can also trigger cell death throu... Read More about Calcium oscillations.

Diatom oxygen isotopes: evidence of a species effect in the sediment record (2007)
Journal Article

Diatom oxygen isotope measurements are commonly made on bulk mixed species assemblages due to the difficulty in purifying and separating individual taxa. As such, it is essential to understand processes in diatoms which may lead to isotope offsets bo... Read More about Diatom oxygen isotopes: evidence of a species effect in the sediment record.

Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes (2007)
Journal Article

Cysteine proteinases from the fruit and latex of plants, such as papaya, pineapple and fig, have previously been shown to have substantial anthelmintic efficacy, in vitro and in vivo, against a range of animal parasitic nematodes. In this paper, we d... Read More about Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes.

New Deal for Disabled People: Third synthesis report – key findings from the evaluation (2007)
Book

Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333) (2007)
Journal Article

Amphetamine enhances recovery after experimental ischaemia and has shown promise in small clinical trials when combined with motor or sensory stimulation. Amphetamine, a sympathomimetic, might have haemodynamic effects in stroke patients, although li... Read More about Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333).

Colony stimulating factors (blood growth factors) are promising but unproven for treating stroke (2007)
Journal Article