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All Outputs (208)

Older adult forensic mental health patients’ views on barriers, facilitators and ‘what works’ to enable better quality of life, health and wellbeing and to reduce risk of reoffending and harm to self and others (2022)
Working Paper

Introduction Research evidence that can inform service provision and treatment requirements for older (aged 55 years and above) forensic mental health patients is lacking, particularly that which is based on patients’ own preferences and experience... Read More about Older adult forensic mental health patients’ views on barriers, facilitators and ‘what works’ to enable better quality of life, health and wellbeing and to reduce risk of reoffending and harm to self and others.

Patient-reported respiratory outcome measures in the recovery of adults hospitalised with COVID-19: A systematic review and meta-analysis (2022)
Working Paper

Background Acute COVID-19 clinical symptoms have been clearly documented, but long-term functional and symptomatic recovery from COVID -19 is less well described. Methods A systematic review and meta-analysis were conducted to describe patient-rep... Read More about Patient-reported respiratory outcome measures in the recovery of adults hospitalised with COVID-19: A systematic review and meta-analysis.

Solutions for Aircraft Electrification Leadership (SAEL)-Driving zero-net carbon aviation through an open global aircraft electrification technology framework (2022)
Working Paper

The SAEL initiative and workshop series was founded in July 2019 in a collaborative effort from international partners from the aerospace industry that include the University of Nottingham, 328 Support Services GmbH, Crane Aerospace & Electronics and... Read More about Solutions for Aircraft Electrification Leadership (SAEL)-Driving zero-net carbon aviation through an open global aircraft electrification technology framework.

Using Patient and Public Involvement to Elicit Opinion on Cognitive Training Games and Assessment Technologies for Dementia (2022)
Working Paper

Background: Cognitive training and assessment technologies offer the promise of dementia risk reduction and more timely diagnosis of dementia respectively. Cognitive training technologies may help to reduce the lifetime risk of dementia by helping... Read More about Using Patient and Public Involvement to Elicit Opinion on Cognitive Training Games and Assessment Technologies for Dementia.

A population framework for predicting the proportion of people infected by the far-field airborne transmission of SARS-CoV-2 indoors (2022)
Working Paper

The number of occupants in a space influences the risk of far-field airborne transmission of SARS-CoV-2 because the likelihood of having infectious and susceptible people both correlate with the number of occupants. This paper explores the relationsh... Read More about A population framework for predicting the proportion of people infected by the far-field airborne transmission of SARS-CoV-2 indoors.

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease (2022)
Working Paper

The genetic component of Alzheimer’s disease (AD) has been mainly assessed using Genome Wide Association Studies (GWAS), which do not capture the risk contributed by rare variants. Here, we compared the gene-based burden of rare damaging variants in... Read More about Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as novel risk factors for Alzheimers Disease.

Human Parainfluenza 2 & 4: clinical and genetic epidemiology in the UK, 2013-2017, reveals distinct disease features and co-circulating genomic subtypes (2022)
Working Paper

Human Parainfluenza viruses (HPIV) are constituted by four members of the genetically distinct genera of Respirovirus (type 1 and 3) and Orthorubulavirus (type 2 and 4), causing significant upper and lower respiratory tract infections in both childre... Read More about Human Parainfluenza 2 & 4: clinical and genetic epidemiology in the UK, 2013-2017, reveals distinct disease features and co-circulating genomic subtypes.

Evaluation of an enhanced training package to support clinical trials training in low and middle income countries (LMICs): experiences from the Born Too Soon Optimising Nutrition study (2021)
Working Paper

Training is essential before working on a clinical trial, yet there is limited evidence on effective training methods. In low and middle income countries (LMICs), training of research staff was considered the second highest priority in a global healt... Read More about Evaluation of an enhanced training package to support clinical trials training in low and middle income countries (LMICs): experiences from the Born Too Soon Optimising Nutrition study.

Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol (2021)
Working Paper

East Midlands Research into Ageing Network (EMRAN) is a research collaboration across the East Midlands to facilitate collaborative applied clinical research into ageing and the care of older people. EMRAN was set up by NIHR CLAHRC East Midlands and... Read More about Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol.

Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol (2021)
Working Paper

Introduction There is a high prevalence of frailty and cognitive impairment within care home population. These wide-ranging experiences and needs impact on residents’ quality of life. Therefore, measuring Quality of Life (QOL) in residents as part... Read More about Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol.

Schengen-pathway controls spatially separated and chemically distinct lignin deposition in the endodermis (2021)
Working Paper

Lignin is a complex polymer precisely deposited in the cell wall of specialised plant cells, where it provides essential cellular functions. Plants coordinate timing, location, abundance and composition of lignin deposition in response to endogenous... Read More about Schengen-pathway controls spatially separated and chemically distinct lignin deposition in the endodermis.