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All Outputs (12)

Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials (2022)
Journal Article
Santer, M., Muller, I., Becque, T., Stuart, B., Hooper, J., Steele, M., …Thomas, K. S. (2022). Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials. BMJ, 379, Article e072007. https://doi.org/10.1136/bmj-2022-072007

Objective: To determine the effectiveness of two online behavioural interventions, one for parents and carers and one for young people, to support eczema self-management. Design: Two independent, pragmatic, parallel group, unmasked, randomised contro... Read More about Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials.

'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema (2022)
Journal Article
Greenwell, K., Sivyer, K., Howells, L., Steele, M., Ridd, M. J., Roberts, A., …Muller, I. (2023). 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema. British Journal of Dermatology, 188(4), 506-513. https://doi.org/10.1093/bjd/ljac115

Background There is a lack of well-conducted randomized controlled trials evaluating the effectiveness of theory-based online interventions for eczema. To address these deficiencies, we previously developed and demonstrated the effectiveness of two o... Read More about 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema.

A realist evaluation of a multifactorial falls prevention programme in care homes (2022)
Journal Article
Leighton, P. A., Darby, J., Allen, F., Cook, M., Evley, R., Fox, C., …Logan, P. (2022). A realist evaluation of a multifactorial falls prevention programme in care homes. Age and Ageing, 51(12), Article afac263. https://doi.org/10.1093/ageing/afac263

BACKGROUND: falls in care homes are common, costly and hard to prevent.Multifactorial falls programmes demonstrate clinical and cost-effectiveness, but the heterogeneity of the care home sector is a barrier to their implementation. A fuller appreciat... Read More about A realist evaluation of a multifactorial falls prevention programme in care homes.

Patient experiences of scaphoid waist fractures and their treatment a qualitative investigation (2022)
Journal Article
Leighton, P. A., Dias, J., & Brearley, S. (2022). Patient experiences of scaphoid waist fractures and their treatment a qualitative investigation. Bone & Joint Open, 3(8), 641-647. https://doi.org/10.1302/2633-1462.38.BJO-2022-0042.R1

Aims To explore individuals’ experience of a scaphoid waist fracture and its subsequent treatment. Methods A purposive sample was created, consisting of 49 participants in the Scaphoid Waist Internal Fixation for Fractures Trial of initial surgery co... Read More about Patient experiences of scaphoid waist fractures and their treatment a qualitative investigation.

Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial (2022)
Journal Article
Topcu, G., Smith, L., Mhizha-Murira, J. R., Goulden, N., Hoare, Z., Drummond, A., …On behalf of the NEuRoMS Collective. (2022). Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial. Pilot and Feasibility Studies, 8(1), Article 123. https://doi.org/10.1186/s40814-022-01073-5

Background: Cognitive problems affect up to 70% of people with multiple sclerosis (MS), which can negatively impact mood, ability to work, and quality of life. Addressing cognitive problems is a top 10 research priority for people with MS. Our ongoin... Read More about Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial.

Prescribing and using vitiligo treatments: lessons from a nested process evaluation within the HI-Light vitiligo randomized controlled trial (2022)
Journal Article
Leighton, P., Chalmers, J. R., Batchelor, J., Rogers, A., Akram, P., Haines, R. H., …Thomas, K. S. (2022). Prescribing and using vitiligo treatments: lessons from a nested process evaluation within the HI-Light vitiligo randomized controlled trial. Clinical and Experimental Dermatology, 47(8), 1480-1489. https://doi.org/10.1111/ced.15193

Background: The HI-Light Trial demonstrated that for active, limited vitiligo, combination treatment with potent topical corticosteroid (TCS) and handheld narrowband ultraviolet B offers a better treatment response than potent TCS alone. However, it... Read More about Prescribing and using vitiligo treatments: lessons from a nested process evaluation within the HI-Light vitiligo randomized controlled trial.

Using the Vitiligo Noticeability Scale in clinical trials: construct validity, interpretability, reliability and acceptability (2022)
Journal Article
Batchelor, J. M., Gran, S., Leighton, P., Howells, L., Montgomery, A. A., Tan, W., …Thomas, K. S. (2022). Using the Vitiligo Noticeability Scale in clinical trials: construct validity, interpretability, reliability and acceptability. British Journal of Dermatology, 187(4), 548-556. https://doi.org/10.1111/bjd.21671

Background: Validated outcome measures are needed for vitiligo trials. Objectives: To assess construct validity, interpretability, reliability and acceptability of the Vitiligo Noticeability Scale (VNS). Methods: We used images of vitiligo before and... Read More about Using the Vitiligo Noticeability Scale in clinical trials: construct validity, interpretability, reliability and acceptability.

ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation): randomised controlled, feasibility trial in older people (2022)
Journal Article
Ong, T., Suazo Di Paola, A., Brookes, C., Drummond, A., Hendrick, P., Leighton, P., …Sahota, O. (2022). ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation): randomised controlled, feasibility trial in older people. BMJ Open, 12(5), Article e050535. https://doi.org/10.1136/bmjopen-2021-050535

Objective To determine the feasibility of designing and conducting a definitive trial to evaluate the effectiveness of sacral fracture fixation compared with non-surgical management among older people admitted with a lateral compression pelvic fragil... Read More about ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation): randomised controlled, feasibility trial in older people.

Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): protocol for a prospective cohort study (2022)
Journal Article
Bates, J., Stanton, H., Cannings-John, R., Thomas, K. S., Leighton, P., Howells, L. M., …Ingram, J. R. (2022). Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): protocol for a prospective cohort study. BMJ Open, 12(4), Article e060815. https://doi.org/10.1136/bmjopen-2022-060815

Background Hidradenitis suppurativa (HS) is a chronic, painful, inflammatory skin disease with estimates of prevalence in the European population of 1%–2%. Despite being a relatively common condition, the evidence base for management of HS is limited... Read More about Treatment of Hidradenitis Suppurativa Evaluation Study (THESEUS): protocol for a prospective cohort study.

The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure (2022)
Journal Article
Gordon, A. L., Rick, C., Juszczak, E., Montgomery, A., Howard, R., Guthrie, B., …Tate, V. (2022). The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure. Age and Ageing, 51(3), Article afac052. https://doi.org/10.1093/ageing/afac052

The COVID-19 pandemic resulted in catastrophic levels of morbidity and mortality for care home residents. Despite this, research platforms for COVID-19 in care homes arrived late in the pandemic compared with other care settings. The Prophylactic The... Read More about The COVID-19 pandemic has highlighted the need to invest in care home research infrastructure.

A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT (2022)
Journal Article
Logan, P. A., Horne, J. C., Allen, F., Armstrong, S. J., Clark, A. B., Conroy, S., …Sims, E. J. (2022). A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT. Health Technology Assessment, 26(9), 1-136. https://doi.org/10.3310/cwib0236

Background Falls in care home residents are common, unpleasant, costly and difficult to prevent. Objectives The objectives were to evaluate the clinical effectiveness and cost-effectiveness of the Guide to Action for falls prevention in Care Hom... Read More about A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT.