All Outputs (10)

Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study (2021)
Journal Article
Maxwell, K., Robinson, J. M., Hoffmann, I., Hou, H. J., Searchfield, G., Baguley, D. M., …Anderson, J. J. (2021). Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study. Otology and Neurotology, 42(10), e1625-e1633. https://doi.org/10.1097/mao.0000000000003369

Objective: To evaluate the safety and exploratory efficacy of intratympanic administration of OTO-313 in patients with tinnitus. Study Design: Single intratympanic injection of OTO-313 evaluated in a randomized, double-blind, placebo-controlle... Read More about Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study.

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study (2021)
Journal Article
Evans, R. A., McAuley, H., Harrison, E. M., Shikotra, A., Singapuri, A., Sereno, M., …Zongo, O. (2021). Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. Lancet Respiratory Medicine, 9(11), 1275-1287. https://doi.org/10.1016/S2213-2600%2821%2900383-0

Background: The impact of COVID-19 on physical and mental health and employment after hospitalisation with acute disease is not well understood. The aim of this study was to determine the effects of COVID-19-related hospitalisation on health and empl... Read More about Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis (2021)
Journal Article
Garinis, A. C., Poling, G. L., Rubenstein, R. C., Konrad-Martin, D., Hullar, T. E., Baguley, D. M., …Brewer, C. C. (2021). Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis. American Journal of Audiology, 30(3S), 800-809. https://doi.org/10.1044/2021_aja-21-00031

Purpose Specific classes of antibiotics, such as aminoglycosides, have well-established adverse events producing permanent hearing loss, tinnitus, and balance and/or vestibular problems (i.e., ototoxicity). Although these antibiotics are frequently u... Read More about Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis.

The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study (2021)
Journal Article
Pearson, S. E., Caimino, C., Shabbir, M., & Baguley, D. M. (2022). The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study. Journal of Cancer Survivorship, 16, 976-987. https://doi.org/10.1007/s11764-021-01089-5

Purpose: This study aimed to explore the burden of inner ear damage (ototoxicity) on adults living with and beyond cancer treated with chemotherapy and the impact on their quality of life (QoL). Furthermore, this study aimed to explore patient awaren... Read More about The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study.

Investigating tinnitus subgroups based on hearing-related difficulties (2021)
Journal Article
Beukes, E. W., Baguley, D. M., Manchaiah, V., Andersson, G., Allen, P. M., Kaldo, V., …Maidment, D. W. (2021). Investigating tinnitus subgroups based on hearing-related difficulties. International Journal of Clinical Practice, 75(10), Article e14684. https://doi.org/10.1111/ijcp.14684

Purpose Meaningfully grouping individuals with tinnitus who share a common characteristics (ie, subgrouping, phenotyping) may help tailor interventions to certain tinnitus subgroups and hence reduce outcome variability. The purpose of this study was... Read More about Investigating tinnitus subgroups based on hearing-related difficulties.

Preferential Cochleotoxicity of Cisplatin (2021)
Journal Article
Prayuenyong, P., Baguley, D. M., Kros, C. J., & Steyger, P. S. (2021). Preferential Cochleotoxicity of Cisplatin. Frontiers in Neuroscience, 15, Article 695268. https://doi.org/10.3389/fnins.2021.695268

Cisplatin-induced ototoxicity in humans is more predominant in the cochlea than in the vestibule. Neither definite nor substantial vestibular dysfunction after cisplatin treatment has been consistently reported in the current literature. Inner ear ha... Read More about Preferential Cochleotoxicity of Cisplatin.

Prevalence of Hyperacusis and Its Relation to Health: The Busselton Healthy Ageing Study (2021)
Journal Article
Smit, A. L., Stegeman, I., Eikelboom, R. H., Baguley, D. M., Bennett, R. J., Tegg-Quinn, S., …Atlas, M. D. (2021). Prevalence of Hyperacusis and Its Relation to Health: The Busselton Healthy Ageing Study. Laryngoscope, 131(12), E2887-E2896. https://doi.org/10.1002/lary.29768

Importance The prevalence of hyperacusis and its relationship with mental and general health is unknown in a nonclinical sample. Therefore, we aimed to determine the prevalence of hyperacusis and its relation with hearing, general and mental health... Read More about Prevalence of Hyperacusis and Its Relation to Health: The Busselton Healthy Ageing Study.

The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review (2021)
Journal Article
Daoud, E., Caimino, C., Akeroyd, M. A., Noreña, A. J., & Baguley, D. M. (2022). The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review. PharmacoEconomics - Open, 6, 21-32. https://doi.org/10.1007/s41669-021-00273-8

Background and objectives Tinnitus is a chronic subjective condition that impacts patients’ health-related quality of life (HRQoL) and requires multidisciplinary interventions. In health economics, quality-adjusted life years (QALYs) and willingness... Read More about The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review.

Hyperacusis：a mini review (2021)
Journal Article
Zhang, D., Xu, Q., & Baguley, D. (2021). Hyperacusis：a mini review. Journal of Clinical Otorhinolaryngology Head and Neck Surgery (临床耳鼻咽喉头颈外科杂志), 2021(6), 563-566

Hyperacusis refers to the experience of the sound environment being perceived as overwhelming loud or painful, and this can severely affect the patient's quality of life. In China little attention has been paid to hyperacusis, and there has been litt... Read More about Hyperacusis：a mini review.

The prevalence of tinnitus in China: a systematic review of the literature (2021)
Journal Article
Dawei, Z., Xu, Q., Caimino, C., & Baguley, D. M. (2021). The prevalence of tinnitus in China: a systematic review of the literature. Journal of Laryngology and Otology, 135(1), 3-9. https://doi.org/10.1017/S002221512000256X

Purpose: The aim of the present study was to identify reports of the prevalence of tinnitus in China and to present these findings in a review format. Method: We assessed and collated published prevalence estimates of tinnitus and tinnitus severity,... Read More about The prevalence of tinnitus in China: a systematic review of the literature.