The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study

Pearson, Stephanie E.; Caimino, Charlotte; Shabbir, Maryam; Baguley, David M.

Abstract

Purpose: This study aimed to explore the burden of inner ear damage (ototoxicity) on adults living with and beyond cancer treated with chemotherapy and the impact on their quality of life (QoL). Furthermore, this study aimed to explore patient awareness surrounding chemotherapy-induced inner ear damage, known as ototoxicity, and assess what support they had been offered. Methods: Participants were adults who had undergone chemotherapy, recruited from cancer clinics, charities and social media. Using semi-structured interviews and fieldnotes, an inductive thematic analysis was used to develop key themes surrounding this topic. Results: Twenty participants from the UK were interviewed. Two key themes were developed from the thematic analysis, cancer-related QoL and ototoxicity-related QoL, with each one including 5 subthemes. Subthemes consisted of impact of ototoxicity, hearing, tinnitus, clinical experience, audiological assessments, and impact of treatment, cancer and chemotherapy, other toxicities, information and patient reflections. Conclusions: Ototoxicity can have a negative impact on QoL, specifically on social life and the fear of hearing loss and/or tinnitus worsening. There are opportunities for increased awareness by patients and clinicians, including improved information sources, and hearing monitoring not onlyfor those undergoing platinum-based chemotherapybut many others surviving after treatment for cancer. Implications for Cancer Survivors: Better monitoring of hearing and information about ototoxicity during chemotherapy could potentially reduce the fear of the symptoms of ototoxicity worsening. Furthermore, hearing monitoring would facilitate the detection of hearing loss at early stagesof survivorship, which would facilitate earlier access to clinical interventions and longer termcounselling.

Citation

Pearson, S. E., Caimino, C., Shabbir, M., & Baguley, D. M. (2022). The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study. Journal of Cancer Survivorship, 16, 976-987. https://doi.org/10.1007/s11764-021-01089-5

• Journal Article Type: Article
• Acceptance Date: Jul 25, 2021
• Online Publication Date: Aug 16, 2021
• Publication Date: 2022-10
• Deposit Date: Jul 27, 2021
• Publicly Available Date: Aug 17, 2022
• Journal: Journal of Cancer Survivorship
• Print ISSN: 1932-2259
• Electronic ISSN: 1932-2267
• Peer Reviewed: Peer Reviewed
• Volume: 16
• Pages: 976-987
• DOI: https://doi.org/10.1007/s11764-021-01089-5
• Public URL: https://nottingham-repository.worktribe.com/output/5841733
• Publisher URL: https://link.springer.com/article/10.1007/s11764-021-01089-5