All Outputs (2666)

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection (2015)
Journal Article

The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly resistant to multiple antibiotics. Here, we investigate the phenotypic and genotyp... Read More about Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection.

Decreased photosynthesis in the erect panicle 3 (ep3) mutant of rice is associated with reduced stomatal conductance and attenuated guard cell development (2015)
Journal Article

The ERECT PANICLE 3 gene of rice encodes a peptide that exhibits more than 50% sequence identity with the Arabidopsis F-box protein HAWAIIAN SKIRT (HWS). Ectopic expression of the Os02g15950 coding sequence, driven by the HWS (At3g61950) promoter, re... Read More about Decreased photosynthesis in the erect panicle 3 (ep3) mutant of rice is associated with reduced stomatal conductance and attenuated guard cell development.

Galaxy And Mass Assembly (GAMA): mass-size relations of z < 0.1 galaxies subdivided by Sersic index, colour and morphology (2015)
Journal Article

© 2015 The Authors. We use data from the Galaxy And Mass Assembly (GAMA) survey in the redshift range 0.01 < z < 0.1 (8399 galaxies in g to Ks bands) to derive the stellar mass-half-light radius relations for various divisions of 'early'- and 'late'-... Read More about Galaxy And Mass Assembly (GAMA): mass-size relations of z < 0.1 galaxies subdivided by Sersic index, colour and morphology.

Developing best practice guidelines on equine colic (2015)
Journal Article

Sarah Freeman and Laila Curtis describe an ongoing project that is aiming to develop evidence-based, best practice guidelines to help owners and veterinary surgeons recognise the signs of colic in horses. They also report on the first of two multidis... Read More about Developing best practice guidelines on equine colic.

Why Good Things Don't Happen: The Micro-foundations of Routines in the M&A Process (2015)
Journal Article

Why do organizations reject favorable opportunities - why don't good things happen? To address this question, we examine companies that fail to proceed with major opportunities for strategic renewal. By focusing upon routines in 28 cases of reverse m... Read More about Why Good Things Don't Happen: The Micro-foundations of Routines in the M&A Process.

Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer (2015)
Journal Article

Recurrence of colorectal cancer (CRC) following a potentially curative resection is a challenging clinical problem. Matrix metalloproteinase-7 (MMP-7) is over-expressed by CRC cells and supposed to play a major role in CRC cell diffusion and metastas... Read More about Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer.

Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age (2015)
Journal Article

Impact of surface chemistry and topography on the function of antigen presenting cells (2015)
Journal Article

Antigen presenting cells (APCs) such as macrophages and dendritic cells (DCs) play a crucial role in orchestrating immune responses against foreign materials. The activation status of APCs can determine the outcome of an immune response following imp... Read More about Impact of surface chemistry and topography on the function of antigen presenting cells.

Performance characteristics of methods for quantifying spontaneous intracerebral haemorrhage: data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial (2015)
Journal Article

Background: Poor prognosis after intracerebral haemorrhage (ICH) is related to haemorrhage characteristics. Along with developing therapeutic interventions, we sought to understand the performance of haemorrhage descriptors in large clinical trials.... Read More about Performance characteristics of methods for quantifying spontaneous intracerebral haemorrhage: data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial.

Stiffness of cold asphalt mixtures with recycled aggregates from construction and demolition waste (2015)
Journal Article

The stiffness of cold asphalt mixtures (CAM) with 100% recycled construction and demolition waste aggregates (CDWA) was studied from three different points of view: the indirect tensile stiffness modulus (ITSM), the dynamic modulus at different tempe... Read More about Stiffness of cold asphalt mixtures with recycled aggregates from construction and demolition waste.

Narrative, Story, and Discourse: The Novium, Chichester (2015)
Journal Article

© 2015 The California Academy of Sciences. This article seeks to engage with the notion of "discourse," and to test and apply ideas from literary and film theory in the analysis of architectural-and particularly museum-space. It examines the complex... Read More about Narrative, Story, and Discourse: The Novium, Chichester.

Identities at odds: embedded and implicit language policing in the internationalized workplace (2015)
Journal Article

This study offers an interaction analytic account of how linguistic identities in internationalized workplaces in Denmark are indexed against members' institutional positions in particular interactional contexts. Where language policy may not be expl... Read More about Identities at odds: embedded and implicit language policing in the internationalized workplace.

The use of virtual reality and physical tools in the development and validation of ease of entry and exit in passenger vehicles (2015)
Journal Article

Ease of entry and exit is important for creating a positive first impression of a car and to increase customer satisfaction. Several methods are used within vehicle development to optimise ease of entry and exit, including CAD reviews, benchmarking... Read More about The use of virtual reality and physical tools in the development and validation of ease of entry and exit in passenger vehicles.

Synthesis of spiroindanes by palladium-catalyzed oxidative annulations of non- or weakly activated 1,3-dienes involving C–H functionalization (2015)
Journal Article

The synthesis of spiroindanes by the palladium-catalyzed oxidative annulation of non- or weakly activated 1,3-dienes with 2-aryl cyclic 1,3-dicarbonyl compounds is described. Examples of the dearomatizing oxidative annulation of 1,3-dienes with 1-ary... Read More about Synthesis of spiroindanes by palladium-catalyzed oxidative annulations of non- or weakly activated 1,3-dienes involving C–H functionalization.

Rethinking the "mirroring" hypothesis: implications for technological modularity, tacit coordination, and radical innovation (2015)
Journal Article

Studies of the 'mirroring' hypothesis have demonstrated the relationships between technological modularity and explicit coordination, yet little is known about the 'mirroring' relationship between technological modularity and tacit coordination, and... Read More about Rethinking the "mirroring" hypothesis: implications for technological modularity, tacit coordination, and radical innovation.

The impact of temperature fluctuations on the large-scale clustering of the Ly? forest (2015)
Journal Article

We develop a semi-analytic method for assessing the impact of the large-scale IGM temperature fluctuations expected following He ii reionization on three-dimensional clustering measurements of the Lyα forest. Our methodology builds upon the existing... Read More about The impact of temperature fluctuations on the large-scale clustering of the Ly? forest.

Archaeogenomic insights into the adaptation of plants to the human environment: Pushing plant-hominin co-evolution back to the Pliocene (2015)
Journal Article

© 2014 The Authors. The colonization of the human environment by plants, and the consequent evolution of domesticated forms is increasingly being viewed as a co-evolutionary plant-human process that occurred over a long time period, with evidence for... Read More about Archaeogenomic insights into the adaptation of plants to the human environment: Pushing plant-hominin co-evolution back to the Pliocene.

Relationship Between White Matter Hyperintensities, Cortical Thickness, and Cognition (2015)
Journal Article

Wiener chaos versus stochastic collocation methods for linear advection-diffusion-reaction equations with multiplicative white noise (2015)
Journal Article

We compare Wiener chaos and stochastic collocation methods for linear advection-reaction-diffusion equations with multiplicative white noise. Both methods are constructed based on a recursive multistage algorithm for long-time integration. We derive... Read More about Wiener chaos versus stochastic collocation methods for linear advection-diffusion-reaction equations with multiplicative white noise.

The use of ?2-agonist therapy before hospital attendance for severe asthma exacerbations: a post-hoc analysis (2015)
Journal Article

Background: Patterns of inhaled β2-agonist therapy use during severe asthma exacerbations before hospital attendance are poorly understood. Aims: To assess β2-agonist use prior to hospital attendance. Methods: We undertook an exploratory pos... Read More about The use of ?2-agonist therapy before hospital attendance for severe asthma exacerbations: a post-hoc analysis.