All Outputs (1156)

Development of a porous poly(DL-lactic acid-co-glycolic acid)-based scaffold for mastoid air-cell regeneration (2013)
Journal Article

Objectives/Hypothesis: To develop a porous, biodegradable scaffold for mastoid air-cell regeneration. Study Design: In vitro development of a temperature-sensitive poly(DL-lactic acid-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG) scaffold tailo... Read More about Development of a porous poly(DL-lactic acid-co-glycolic acid)-based scaffold for mastoid air-cell regeneration.

A practical drug discovery project at the undergraduate level (2013)
Journal Article

A practical drug discovery project for third-year undergraduates is described. No previous knowledge of medicinal chemistry is assumed. Initial lecture-workshops cover the basic principles; then students are asked to improve the profile of a weakly... Read More about A practical drug discovery project at the undergraduate level.

Experiences of family carers of older people with mental health problems in the acute general hospital: a qualitative study (2013)
Journal Article

Aims To explore the experiences of family carers of people with cognitive impairment during admission to hospital. Background Providing appropriate care in acute hospitals for people with co-morbid cognitive impairment, especially dementia or de... Read More about Experiences of family carers of older people with mental health problems in the acute general hospital: a qualitative study.

Translating Patient-Oriented Eczema Measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor-based methods (2013)
Journal Article

Background: The Patient-Oriented Eczema Measure (POEM) is a validated, patient-derived assessment measure for monitoring atopic eczema severity, although further information on how different POEM scores translate into disease severity categories is n... Read More about Translating Patient-Oriented Eczema Measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor-based methods.

Hyper-heuristics: a survey of the state of the art (2013)
Journal Article

Hyper-heuristics comprise a set of approaches that are motivated (at least in part) by the goal of automating the design of heuristic methods to solve hard computational search problems. An underlying strategic research challenge is to develop more g... Read More about Hyper-heuristics: a survey of the state of the art.

Pseudodynamic tests on a full-scale 3-storey precast concrete building: behavior of the mechanical connections and floor diaphragms (2013)
Journal Article

A full-scale three-storey precast building was tested under seismic conditions at the European Laboratory for Structural Assessment in the framework of the SAFECAST project. The unique research opportunity of testing a complete structural system was... Read More about Pseudodynamic tests on a full-scale 3-storey precast concrete building: behavior of the mechanical connections and floor diaphragms.

Rationalizing the value premium in emerging markets (2013)
Journal Article

We reconfirm the presence of value premium in emerging markets. Using the Brazil–Turkey–India–China (BTIC) grouping during a period of substantial economic growth and stock market development, we attribute the premium to the investment patterns of gl... Read More about Rationalizing the value premium in emerging markets.

Prioritization of combinatorial test cases by incremental interaction coverage (2013)
Journal Article

Combinatorial testing is a well-recognized testing method, and has been widely applied in practice. To facilitate analysis, a common approach is to assume that all test cases in a combinatorial test suite have the same fault detection capability. How... Read More about Prioritization of combinatorial test cases by incremental interaction coverage.

Nanotechnology tracks to the renal ward (2013)
Journal Article

Controlled flax interventions for the improvement of menopausal symptoms and postmenopausal bone health: a systematic review (2013)
Journal Article

Concerns regarding hormone therapy safety have led to interest in the use of phytoestrogens for a variety of menopause-related health complaints. Recent meta-analyses concerning soy and postmenopausal bone mineral density, flax and serum cholesterol... Read More about Controlled flax interventions for the improvement of menopausal symptoms and postmenopausal bone health: a systematic review.

Quantification of changes in zero valent iron morphology using X-ray computed tomography (2013)
Journal Article

Morphological changes within the porous architecture of laboratory scale zero valent iron (ZVI) permeable reactive barriers (PRBs), after exposure to different groundwater conditions, have been quantified experimentally for different ZVI/sand ratios... Read More about Quantification of changes in zero valent iron morphology using X-ray computed tomography.

On the robustness of entanglement in analogue gravity systems (2013)
Journal Article

We investigate the possibility of generating quantum-correlated quasi-particles utilizing analogue gravity systems. The quantumness of these correlations is a key aspect of analogue gravity effects and their presence allows for a clear separation bet... Read More about On the robustness of entanglement in analogue gravity systems.

Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution (2013)
Journal Article

© 2013, The Author(s). Many modern statistical applications involve inference for complicated stochastic models for which the likelihood function is difficult or even impossible to calculate, and hence conventional likelihood-based inferential techni... Read More about Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution.

Discrete element modelling of one-dimensional compression of cemented sand (2013)
Journal Article

It has recently been shown that the one-dimensional normal compression of sand can be modelled effectively in three-dimensions using the discrete element method, and that the slope of the compression curve (in log voids ratio–log stress space) is con... Read More about Discrete element modelling of one-dimensional compression of cemented sand.

Talking about sex after traumatic brain injury: perceptions and experiences of multidisciplinary rehabilitation professionals (2013)
Journal Article

Purpose: Research indicates that although 50–60% of people who have had a traumatic brain injury (TBI) experience changes in sexual functioning, sexuality issues remain largely unaddressed in rehabilitation. This study aimed to explore rehabilitation... Read More about Talking about sex after traumatic brain injury: perceptions and experiences of multidisciplinary rehabilitation professionals.

Peptide ligation chemistry at selenol amino acids (2013)
Journal Article

The convergent assembly of peptide fragments by native chemical ligation has revolutionized the way in which proteins can be accessed by chemical synthesis. A variation of native chemical ligation involves the reaction of peptides bearing an N‐termin... Read More about Peptide ligation chemistry at selenol amino acids.

Uptake and transport of B12-conjugated nanoparticles in airway epithelium (2013)
Journal Article

Non-invasive delivery of biotherapeutics, as an attractive alternative to injections, could potentially be achieved through the mucosal surfaces, utilizing nanoscale therapeutic carriers. However, nanoparticles do not readily cross the mucosal barrie... Read More about Uptake and transport of B12-conjugated nanoparticles in airway epithelium.

Motor excitability during movement preparation in Tourette syndrome (2013)
Journal Article

Tourette syndrome (TS) is a neurodevelopmental disorder characterized by the occurrence of motor and vocal tics. TS has been linked to the impaired operation of cortical-striatal-thalamic-cortical circuits that give rise to hyper-excitability of cort... Read More about Motor excitability during movement preparation in Tourette syndrome.

Innovating responses to managing risk: exploring the potential of a victim-focused policing strategy (2013)
Journal Article

This article explores the potential benefits of developing partnerships with victims in managing threats to their personal safety via smart police use of electronic monitoring technologies. The central premise for this position is that traditional su... Read More about Innovating responses to managing risk: exploring the potential of a victim-focused policing strategy.

Examination of moisture sensitivity of aggregate-bitumen bonding strength using loose asphalt mixture and physico-chemical surface energy property tests (2013)
Journal Article

In this study, the moisture sensitivity of different kinds of aggregates and bituminous binders is examined by comparing the performance between five empirical test methods for loose mixtures - static immersion test, rolling bottle test (RBT), boilin... Read More about Examination of moisture sensitivity of aggregate-bitumen bonding strength using loose asphalt mixture and physico-chemical surface energy property tests.