All Outputs (404)

A clozapine-like effect of cyproheptadine on progressive ratio schedule performance (2011)
Journal Article

The atypical antipsychotic drug clozapine has multiple pharmacological actions, some of which, including 5-hydroxytryptamine (5-HT2) and histamine (H1) receptor antagonist effects, are shared by the non-selective 5-HT receptor antagonist cyproheptadi... Read More about A clozapine-like effect of cyproheptadine on progressive ratio schedule performance.

Carriage of meningococci by university students, United Kingdom (2011)
Journal Article

How neutral is the intergalactic medium surrounding the redshift z=7.085 quasar ULAS J1120+0641? (2011)
Journal Article

The quasar ULAS J1120+0641 at redshift z=7.085 has a highly ionised near zone which is smaller than those around quasars of similar luminosity at z~6. The spectrum also exhibits evidence for a damping wing extending redward of the systemic Lya redshi... Read More about How neutral is the intergalactic medium surrounding the redshift z=7.085 quasar ULAS J1120+0641?.

‘Do as I say, but not as I do’: are next generation nurses role models for health? (2011)
Journal Article

Aim: Promoting healthy lifestyles plays a key role in professional nursing yet nurses do not always practice what they preach. Efforts are currently being made to improve the health of NHS staff, yet little is known about the health and lifestyle beh... Read More about ‘Do as I say, but not as I do’: are next generation nurses role models for health?.

Slow, slow, quick, quick, slow: retrospective conversion at the University of Nottingham (2011)
Journal Article

Safety of new medicines in young children (2011)
Journal Article

Functional network construction in Arabidopsis using rule-based machine learning on large-scale data sets (2011)
Journal Article

The meta-analysis of large-scale postgenomics data sets within public databases promises to provide important novel biological knowledge. Statistical approaches including correlation analyses in coexpression studies of gene expression have emerged as... Read More about Functional network construction in Arabidopsis using rule-based machine learning on large-scale data sets.

Sun safety measures among construction workers in Britain (2011)
Journal Article

Background: Relative to other occupational groups in Britain, construction workers have a high incidence of skin cancer attributable to sun exposure. The importance of sun safety measures to minimize the risk of skin cancer is recognized in the liter... Read More about Sun safety measures among construction workers in Britain.

Delayed publications of clinical trials in cystic fibrosis (2011)
Journal Article

Background: When the publication of important trial data is delayed, or data are never published, this will prevent the proper practice of evidence based medicine through robust systematic reviews. Clinical trial registries allow researchers to... Read More about Delayed publications of clinical trials in cystic fibrosis.

Quiet in class: classification, noise and the dendritic cell algorithm (2011)
Journal Article

Theoretical analyses of the Dendritic Cell Algorithm (DCA) have yielded several criticisms about its underlying structure and operation. As a result, several alterations and fixes have been suggested in the literature to correct for these findings. A... Read More about Quiet in class: classification, noise and the dendritic cell algorithm.

A converse theorem for double Dirichlet series (2011)
Journal Article

We prove that a certain vector valued double Dirichlet series satisfying appropriate functional equations is a Mellin transform of a vector valued metaplectic Eisenstein series. We establish an analogous result for scalar double Dirichlet series of t... Read More about A converse theorem for double Dirichlet series.

Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis (2011)
Journal Article

Purpose: Antimicrobial peptides (AMPs) and toll-like receptors (TLRs) form part of the “chemical barrier” of the ocular surface to microbes. Evidence suggests that pathogen recognition by TLR releases AMPs, altering AMP-TLR profiles in pathologic... Read More about Increased Expression of Hepcidin and Toll-Like Receptors 8 and 10 in Viral Keratitis.

Correlation of central and peripheral corneal thickness in healthy corneas (2011)
Journal Article

Purpose To study the thickness profile of the normal cornea in order to establish any correlation between central and peripheral points. Methods Sixty-seven eyes of 40 patients were subjected to central corneal thickness measurement (CCT) with a... Read More about Correlation of central and peripheral corneal thickness in healthy corneas.

Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome (2011)
Journal Article

Variability among individuals in the severity of fragile X syndrome (FXS) is influenced by epigenetic methylation mosaicism, which may also be common in other complex disorders. The epigenetic signal of dense promoter DNA methylation is usually assoc... Read More about Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome.

What factors influence smoking prevalence and smoke free policy enactment across the European Union Member States (2011)
Journal Article

Background Smoking prevention should be a primary public health priority for all governments, and effective preventive policies have been identified for decades. The heterogeneity of smoking prevalence between European Union (EU) Member States the... Read More about What factors influence smoking prevalence and smoke free policy enactment across the European Union Member States.

Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human ?-adrenoceptors (2011)
Journal Article

The growing practice of exploiting noninvasive fluorescence-based techniques to study G protein-coupled receptor pharmacology at the single cell and single molecule level demands the availability of high-quality fluorescent ligands. To this end, this... Read More about Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human ?-adrenoceptors.

The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization (2011)
Journal Article

Unlike other kinesins, members of the kinesin-13 subfamily do not move directionally along microtubules but, instead, depolymerize them. To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucida... Read More about The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.

Can human amblyopia be treated in adulthood? (2011)
Journal Article

Amblyopia is a common visual disorder that results in a spatial acuity deficit in the affected eye. Orthodox treatment is to occlude the unaffected eye for lengthy periods, largely determined by the severity of the visual deficit at diagnosis. Althou... Read More about Can human amblyopia be treated in adulthood?.

Drawing to learn in science (2011)
Journal Article

Carbon nanotube/titanium dioxide (CNT/TiO2) core-shell nanocomposites with tailored shell thickness, CNT content and photocatalytic/photoelectrocatalytic properties (2011)
Journal Article

Combining carbon nanotubes (CNTs) with TiO2 at the nano-scale level can promote the separation of the electron-hole charges generated upon irradiation. However, charge separation capability depends on the quality of the interfacial contact between CN... Read More about Carbon nanotube/titanium dioxide (CNT/TiO2) core-shell nanocomposites with tailored shell thickness, CNT content and photocatalytic/photoelectrocatalytic properties.