All Outputs (191)

Idiotypic Immune Networks in Mobile-Robot Control (2007)
Journal Article

Jerne's idiotypic network theory postulates that the immune response involves inter-antibody stimulation and suppression as well as matching to antigens. The theory has proved the most popular Artificial Immune System (AIS) model for incorporation in... Read More about Idiotypic Immune Networks in Mobile-Robot Control.

An estimation of distribution algorithm with intelligent local search for rule-based nurse rostering (2007)
Journal Article

This paper proposes a new memetic evolutionary algorithm to achieve explicit learning in rule-based nurse rostering, which involves applying a set of heuristic rules for each nurse's assignment. The main framework of the algorithm is an estimation of... Read More about An estimation of distribution algorithm with intelligent local search for rule-based nurse rostering.

Towards improving the utilization of university teaching space (2007)
Journal Article

There is a perception that teaching space in universities is a rather scarce resource. However, some studies have revealed that in many institutions it is actually chronically under-used. Often, rooms are occupied only half the time, and even when in... Read More about Towards improving the utilization of university teaching space.

Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics (2007)
Journal Article

Mucosal human papillomaviruses (HPVs) are etiological agents of oral, anal and genital cancer. Properties of high- and low-risk HPV types cannot be reduced to discrete molecular traits. The E2 protein regulates viral replication and transcription thr... Read More about Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics.

The fermion spectrum in braneworld collisions (2007)
Journal Article

In braneworld collisions fermions originally localised on one brane can be transferred to another brane, or to a space-time boundary. By modelling branes as scalar field kinks we bounce them off boundaries and study resulting effects according to a b... Read More about The fermion spectrum in braneworld collisions.

Early life stress causes FG-7142-induced corticolimbic dysfunction in adulthood (2007)
Journal Article

Maternal separation (MS) during the neonatal period enhances stress responsivity in adulthood. The medial prefrontal cortex (mPFC) and the basolateral amygdala (BLA) are involved in coordinating various stress responses. Evidence indicates that MS re... Read More about Early life stress causes FG-7142-induced corticolimbic dysfunction in adulthood.

An immunoglobulin E-reactive chimeric human immunoglobulin G1 anti-idiotype inhibits basophil degranulation through cross-linking of FcεRI with FcγRIIb (2007)
Journal Article

Background: IgE binds to mast cells and basophils via its high-affinity receptor, FcεRI, and cross-linking of FcεRI-bound IgE molecules by allergen leads to the release of allergic mediators characteristic of type I hypersensitivity reactions. Previo... Read More about An immunoglobulin E-reactive chimeric human immunoglobulin G1 anti-idiotype inhibits basophil degranulation through cross-linking of FcεRI with FcγRIIb.

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge (2007)
Journal Article

A major problem in hepatitis C virus (HCV) immunotherapy or vaccine design is the extreme variability of the virus. We identified human monoclonal antibodies (mAbs) that neutralize genetically diverse HCV isolates and protect against heterologous HCV... Read More about Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge.

Reionization bias in high-redshift quasar near-zones (2007)
Journal Article

Nuclear weapons and intergenerational exploitation (2007)
Journal Article

Nuclear weapons’ defenders claim that they lower the risk of war, at the price of devastation if war breaks out. But sooner or later, on a realist analysis, catastrophic nuclear war is almost sure to come. Nuclear deterrence thus buys us a better cha... Read More about Nuclear weapons and intergenerational exploitation.

Immune system approaches to intrusion detection - a review (2007)
Journal Article

The use of artificial immune systems in intrusion detection is an appealing concept for two reasons. Firstly, the human immune system provides the human body with a high level of protection from invading pathogens, in a robust, self-organised and dis... Read More about Immune system approaches to intrusion detection - a review.

Anisotropic Assembly of Colloidal Nanoparticles: Exploiting Substrate Crystallinity (2007)
Journal Article

We show that the crystal structure of a substrate can be exploited to drive the anisotropic assembly of colloidal nanoparticles. Pentanethiol-passivated Au particles of approximately 2 nm diameter deposited from toluene onto hydrogen-passivated Si(11... Read More about Anisotropic Assembly of Colloidal Nanoparticles: Exploiting Substrate Crystallinity.

Ontogeny and nutritional programming of mitochondrial proteins in the ovine kidney, liver and lung (2007)
Journal Article

This study investigated the developmental and nutritional programming of two important mitochondrial proteins, namely voltage dependent anion channel (VDAC) and cytochrome c in the sheep kidney, liver and lung. The effect of maternal nutrient restric... Read More about Ontogeny and nutritional programming of mitochondrial proteins in the ovine kidney, liver and lung.

Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndrome (2007)
Journal Article

Objective. Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an inherited autosomal-dominant autoinflammatory condition caused by mutations in the ectodomain of the 55-kd tumor necrosis factor (TNF) receptor superfamily 1A. Proin... Read More about Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndrome.

Cosmology with twisted tori (2007)
Journal Article

We consider the cosmological role of the scalar fields generated by the compactification of 11-dimensional Einstein gravity on a 7D elliptic twisted torus, which has the attractive features of giving rise to a positive semi-definite potential, and pa... Read More about Cosmology with twisted tori.

Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels (2007)
Journal Article

Environmental factors (e.g. stress, exercise, enrichment) are thought to play a role in the development of Alzheimer's disease later in life. We investigated the influence of repeated novel cage exposure on the development of early Alzheimer's-like p... Read More about Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels.

Geographies of business education: MBA programmes, reflexive business schools and the cultural circuit of capital (2007)
Journal Article

MBA programmes and the business schools that teach them have been identified by geographers and social scientists as central actors in the dissemination of economic and management theories into practice through concepts such as the cultural circuit o... Read More about Geographies of business education: MBA programmes, reflexive business schools and the cultural circuit of capital.

An improved measurement of the flux distribution of the Ly-alpha forest in QSO absorption spectra: the effect of continuum fitting, metal contamination and noise properties (2007)
Journal Article

We have performed an extensive Voigt profile analysis of the neutral hydrogen (HI) and metal absorption present in a sample of 18 high resolution, high signal-to-noise QSO spectra observed with VLT/UVES. We use this analysis to separate the metal con... Read More about An improved measurement of the flux distribution of the Ly-alpha forest in QSO absorption spectra: the effect of continuum fitting, metal contamination and noise properties.

A 140-year record of recent changes in aquatic productivity in a remote, tropical alpine lake in the Rwenzori Mountain National Park, Uganda (2007)
Journal Article

Environmental change in many tropical, alpine habitats remains poorly resolved due to an absence of proximate and sustained observations. In the Rwenzori Mountains of East Africa, glaciers have receded rapidly over the last century, and here we asses... Read More about A 140-year record of recent changes in aquatic productivity in a remote, tropical alpine lake in the Rwenzori Mountain National Park, Uganda.

Singular manifolds, topology change and the dynamics of compactification (2007)
Journal Article

We investigate the dynamics of the geometric transitions associated to compactified spacetimes. By including the dynamics of gravity we are able to follow the evolution of collapsing cycles as they attempt to undergo a topology changing transition. R... Read More about Singular manifolds, topology change and the dynamics of compactification.