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Databases "sui generis" right: should we adopt the spin-off theory? (2004)
Journal Article
Derclaye, E. (2004). Databases "sui generis" right: should we adopt the spin-off theory?. European Intellectual Property Review, 26(9),

Eight years have passed since the Database Directive was enacted. A relatively abundant body of case law has now emerged but courts remain divided or uncertain over a number of issues. One of them is the most important question of the protection re... Read More about Databases "sui generis" right: should we adopt the spin-off theory?.

Variation in the helminth community structure in spiny mice (Acomys dimidiatus) from four montane wadis in the St Katherine region of the Sinai Peninsula in Egypt (2004)
Journal Article
Behnke, J. M., Harris, P. D., Bajer, A., Barnard, C. J., Sherif, N. E., Cliffe, L., …Zalat, S. (2004). Variation in the helminth community structure in spiny mice (Acomys dimidiatus) from four montane wadis in the St Katherine region of the Sinai Peninsula in Egypt. Parasitology, 129(3), https://doi.org/10.1017/S003118200400558X

We compared helminth communities in spiny mice (Acomys dimidiatus) from 4 wadis in the arid montane region of the southern Sinai in Egypt, in a 4-week period in late summer. Total helminth species richness was 14 (8 nematodes, 5 cestodes and 1 acanth... Read More about Variation in the helminth community structure in spiny mice (Acomys dimidiatus) from four montane wadis in the St Katherine region of the Sinai Peninsula in Egypt.

High glucose mediates prooxidant and antioxidant enzyme activities in coronary endothelial cells (2004)
Journal Article
Bayraktutan, U., Weidig, P., McMaster, D., & Ulker, S. (2004). High glucose mediates prooxidant and antioxidant enzyme activities in coronary endothelial cells

Objective: Excess levels of free radicals such as nitric oxide (NO) and superoxide anion (O2-)are associated with the pathogenesis of endothelial cell dysfunction in diabetes mellitus. This study was designed to investigate the underlying causes of o... Read More about High glucose mediates prooxidant and antioxidant enzyme activities in coronary endothelial cells.

Nitric oxide synthase and NAD(P)H oxidase modulate coronary endothelial cell growth (2004)
Journal Article
Bayraktutan, U. (2004). Nitric oxide synthase and NAD(P)H oxidase modulate coronary endothelial cell growth. Journal of Molecular and Cellular Cardiology, 36,

Reactive oxygen species (ROS) including nitric oxide (NO) and superoxide anion (O2-) are associated with cell migration, proliferation and many growth-related diseases. The objective of this study was to determine whether there was a reciprocal relat... Read More about Nitric oxide synthase and NAD(P)H oxidase modulate coronary endothelial cell growth.

Poor encoding of position by contrast-defined motion (2004)
Journal Article
Allen, H. A., Ledgeway, T., & Hess, R. F. (2004). Poor encoding of position by contrast-defined motion. Vision Research, 44(17), https://doi.org/10.1016/j.visres.2004.03.025

Second-order (contrast-defined) motion stimuli lead to poor performance on a number of tasks, including discriminating form from motion and visual search. To investigate this deficiency, we tested the ability of human observers to monitor multiple re... Read More about Poor encoding of position by contrast-defined motion.

Building Better Nurse Scheduling Algorithms (2004)
Journal Article
Aickelin, U., & White, P. (2004). Building Better Nurse Scheduling Algorithms. Annals of Operations Research, 128, https://doi.org/10.1023/B%3AANOR.0000019103.31340.a6

The aim of this research is twofold: Firstly, to model and solve a complex nurse scheduling problem with an integer programming formulation and evolutionary algorithms. Secondly, to detail a novel statistical method of comparing and hence building be... Read More about Building Better Nurse Scheduling Algorithms.

An Indirect Genetic Algorithm for a Nurse Scheduling Problem (2004)
Journal Article
Aickelin, U., & Dowsland, K. (2004). An Indirect Genetic Algorithm for a Nurse Scheduling Problem. Computers and Operations Research, 31(5), https://doi.org/10.1016/S0305-0548%2803%2900034-0

This paper describes a Genetic Algorithms approach to a manpower-scheduling problem arising at a major UK hospital. Although Genetic Algorithms have been successfully used for similar problems in the past, they always had to overcome the limitations... Read More about An Indirect Genetic Algorithm for a Nurse Scheduling Problem.

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors (2004)
Journal Article
Ahmed, B., Chakravarthy, S., Eggers, R., Hermens, W., Zhang, J., Niclou, S., …Verhaagen, J. (2004). Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors. BMC Neuroscience, 5(1), Article 4. https://doi.org/10.1186/1471-2202-5-4

BACKGROUND: Inactivating genes in vivo is an important technique for establishing their function in the adult nervous system. Unfortunately, conventional knockout mice may suffer from several limitations including embryonic or perinatal lethality and... Read More about Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors.