All Outputs (51)

Quantification of GABA, glutamate and glutamine in a single measurement at 3 T using GABA-edited MEGA-PRESS (2017)
Journal Article
Nezhad, F. S., Anton, A., Michou, E., Jung, J., Parkes, L. M., & Williams, S. R. (2018). Quantification of GABA, glutamate and glutamine in a single measurement at 3 T using GABA-edited MEGA-PRESS. NMR in Biomedicine, 31(1), Article e3847. https://doi.org/10.1002/nbm.3847

γ-Aminobutyric acid (GABA) and glutamate (Glu), major neurotransmitters in the brain, are recycled through glutamine (Gln). All three metabolites can be measured by magnetic resonance spectroscopy in vivo, although GABA measurement at 3T requires an... Read More about Quantification of GABA, glutamate and glutamine in a single measurement at 3 T using GABA-edited MEGA-PRESS.

A spiral attractor network drives rhythmic locomotion (2017)
Journal Article
Bruno, A. M., Frost, W. N., & Humphries, M. D. (2017). A spiral attractor network drives rhythmic locomotion. eLife, 6, doi:10.7554/elife.27342. ISSN 2050-084X

The joint activity of neural populations is high dimensional and complex. One strategy for reaching a tractable understanding of circuit function is to seek the simplest dynamical system that can account for the population activity. By imaging Aplysi... Read More about A spiral attractor network drives rhythmic locomotion.

Role of the Cerebellum in Adaptation to Delayed Action Effects (2017)
Journal Article
Cao, L., Veniero, D., Thut, G., & Gross, J. (2017). Role of the Cerebellum in Adaptation to Delayed Action Effects. Current Biology, 27(16), 2442-2451.e3. https://doi.org/10.1016/j.cub.2017.06.074

© 2017 The Author(s) Actions are typically associated with sensory consequences. For example, knocking at a door results in predictable sounds. These self-initiated sensory stimuli are known to elicit smaller cortical responses compared to passively... Read More about Role of the Cerebellum in Adaptation to Delayed Action Effects.

Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPAR?) are disrupted by retinal disease-associated mutations (2017)
Journal Article
Fulton, J., Mazumder, B., Whitchurch, J., Monteiro, C. J., Collins, H. M., Chan, C. M., …Heery, D. M. (2017). Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations. Cell Death and Disease, 8, Article e2677. https://doi.org/10.1038/cddis.2017.98

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the Nuclear Receptor (NR) superfamily of transcription factors. We assessed... Read More about Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPAR?) are disrupted by retinal disease-associated mutations.

Homeostatic plasticity for single node delay-coupled reservoir computing (2015)
Journal Article
Toutounji, H., Schumacher, J., & Pipa, G. (2015). Homeostatic plasticity for single node delay-coupled reservoir computing. Neural Computation, 27(6), 1159-1185. https://doi.org/10.1162/NECO_a_00737

© 2015 Massachusetts Institute of Technology. Supplementing a differential equation with delays results in an infinitedimensional dynamical system. This property provides the basis for a reservoir computing architecture, where the recurrent neural ne... Read More about Homeostatic plasticity for single node delay-coupled reservoir computing.

Modular deconstruction reveals the dynamical and physical building blocks of a locomotion motor program (2015)
Journal Article
Bruno, A., Frost, W., & Humphries, M. (2015). Modular deconstruction reveals the dynamical and physical building blocks of a locomotion motor program. Neuron, 86(1), (304-318). doi:10.1016/j.neuron.2015.03.005. ISSN 0896-6273

The neural substrates of motor programs are only well understood for small, dedicated circuits. Here we investigate how a motor program is constructed within a large network. We imaged populations of neurons in the Aplysia pedal ganglion during execu... Read More about Modular deconstruction reveals the dynamical and physical building blocks of a locomotion motor program.

A new framework for cortico-striatal plasticity: behavioural theory meets In vitro data at the reinforcement-action interface (2015)
Journal Article
Gurney, K. N., Humphries, M. D., & Redgrave, P. (2015). A new framework for cortico-striatal plasticity: behavioural theory meets In vitro data at the reinforcement-action interface. PLoS Biology, 13(1), doi:10.1371/journal.pbio.1002034. ISSN 1544-9173

Operant learning requires that reinforcement signals interact with action representations at a suitable neural interface. Much evidence suggests that this occurs when phasic dopamine, acting as a reinforcement prediction error, gates plasticity at co... Read More about A new framework for cortico-striatal plasticity: behavioural theory meets In vitro data at the reinforcement-action interface.

Attentional Modulation of Alpha/Beta and Gamma Oscillations Reflect Functionally Distinct Processes (2014)
Journal Article
Bauer, M., Stenner, M., Friston, K. J., & Dolan, R. J. (2014). Attentional Modulation of Alpha/Beta and Gamma Oscillations Reflect Functionally Distinct Processes. Journal of Neuroscience, 34(48), 16117-16125. https://doi.org/10.1523/JNEUROSCI.3474-13.2014

The projected hand illusion: component structure in a community sample and association with demographics, cognition, and psychotic-like experiences (2014)
Journal Article
Graham, K. T., Martin-Iverson, M. T., Holmes, N. P., & Waters, F. A. (2015). The projected hand illusion: component structure in a community sample and association with demographics, cognition, and psychotic-like experiences. Attention, Perception, and Psychophysics, 77(1), 207-219. doi:10.3758/s13414-014-0748-6

The projected hand illusion (PHI) is a variant of the rubber hand illusion (RHI), and both are commonly used to study mechanisms of self-perception. A questionnaire was developed by Longo et al. (2008) to measure qualitative changes in the RHI. Such... Read More about The projected hand illusion: component structure in a community sample and association with demographics, cognition, and psychotic-like experiences.

Testing theories of irony processing using eye-tracking and ERPs (2014)
Journal Article
Filik, R., Leuthold, H., Wallington, K., & Page, J. (2014). Testing theories of irony processing using eye-tracking and ERPs. Journal of Experimental Psychology: Learning, Memory, and Cognition, 40(3), 811-828. https://doi.org/10.1037/a0035658

Not much is known about how people comprehend ironic utterances, and to date, most studies have simply compared processing of ironic versus non-ironic statements. A key aspect of the graded salience hypothesis, distinguishing it from other accounts (... Read More about Testing theories of irony processing using eye-tracking and ERPs.

Behavior control in the sensorimotor loop with short-term synaptic dynamics induced by self-regulating neurons (2014)
Journal Article
Toutounji, H., & Pasemann, F. (2014). Behavior control in the sensorimotor loop with short-term synaptic dynamics induced by self-regulating neurons. Frontiers in Neurorobotics, 8, https://doi.org/10.3389/fnbot.2014.00019

The behavior and skills of living systems depend on the distributed control provided by specialized and highly recurrent neural networks. Learning and memory in these systems is mediated by a set of adaptation mechanisms, known collectively as neuron... Read More about Behavior control in the sensorimotor loop with short-term synaptic dynamics induced by self-regulating neurons.