All Outputs (5)

Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study (2011)
Journal Article
Farrell, T. L., Poquet, L., Dew, T. P., Barber, S., & Williamson, G. (2012). Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study. Drug Metabolism and Disposition, 40(2), 397-406. https://doi.org/10.1124/dmd.111.041665

There is a considerable need to rationalize the membrane permeability and mechanism of transport for potential nutraceuticals. The aim of this investigation was to develop a theoretical permeability equation, based on a reported descriptive absorptio... Read More about Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study.

Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers (2011)
Journal Article
Farrell, T. L., Dew, T. P., Poquet, L., Hanson, P., & Williamson, G. (2011). Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers. Drug Metabolism and Disposition, 39(12), 2338-2346. https://doi.org/10.1124/dmd.111.040147

Gastric absorption of feruloylquinic acid and di-O-caffeoylquinic acid analogs has never been investigated despite their potential contribution to the proposed beneficial health effects leading to reduced risk of type 2 diabetes. Using a cultured gas... Read More about Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers.

Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials (2011)
Journal Article
Williamson, G., Coppens, P., Serra-Majem, L., & Dew, T. (2011). Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials. Food and Function, 2(12), 753-759. https://doi.org/10.1039/c1fo10101c

We assess the evidence for health benefits of three commonly consumed plant food supplements (PFS), green tea, isoflavone and aloe vera, based on published systematic reviews of randomised controlled trials (RCTs). Whilst the potential benefits of gr... Read More about Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials.

Influence of Combined Biotic and Abiotic Stress on Nutritional Quality Parameters in Tomato (Solanum lycopersicum) (2011)
Journal Article
Atkinson, N. J., Dew, T. P., Orfila, C., & Urwin, P. E. (2011). Influence of Combined Biotic and Abiotic Stress on Nutritional Quality Parameters in Tomato (Solanum lycopersicum). Journal of Agricultural and Food Chemistry, 59(17), 9673-9682. https://doi.org/10.1021/jf202081t

Induction of abiotic stress in tomato plants has been proposed as a mechanism for improving the nutritional quality of fruits. However, the occurrence of biotic stress can interfere with normal abiotic stress responses. In this study, the combined ef... Read More about Influence of Combined Biotic and Abiotic Stress on Nutritional Quality Parameters in Tomato (Solanum lycopersicum).

Epigallocatechin-3-gallate Inhibits Lactase but Is Alleviated by Salivary Proline-Rich Proteins (2011)
Journal Article
Naz, S., Siddiqi, R., Dew, T. P., & Williamson, G. (2011). Epigallocatechin-3-gallate Inhibits Lactase but Is Alleviated by Salivary Proline-Rich Proteins. Journal of Agricultural and Food Chemistry, 59(6), 2734-2738. https://doi.org/10.1021/jf103072z

Lactase phlorizin hydrolase is a small intestinal brush border enzyme that catalyzes the hydrolysis of the milk sugar, lactose, and also many flavonoid glucosides. We demonstrate that epigallocatechin-3-gallate (EGCG), the principal flavonoid from gr... Read More about Epigallocatechin-3-gallate Inhibits Lactase but Is Alleviated by Salivary Proline-Rich Proteins.