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Efficacy and safety of intensive versus conventional glucose targets in people with type 2 diabetes: a systematic review and meta-analysis (2023)
Journal Article
Aldafas, R., Crabtree, T., Vinogradova, Y., Gordon, J. P., & Idris, I. (2023). Efficacy and safety of intensive versus conventional glucose targets in people with type 2 diabetes: a systematic review and meta-analysis. Expert Review of Endocrinology and Metabolism, 18(1), 95-110. https://doi.org/10.1080/17446651.2023.2166489

Objective: The aim of study is to re-evaluate the risk-benefits of intensive glycemic control in the context of multi-factorial intervention in adults with T2D. Methods: We searched Ovid MEDLINE, Embase, Cochrane, and CINHAL for randomized contro... Read More about Efficacy and safety of intensive versus conventional glucose targets in people with type 2 diabetes: a systematic review and meta-analysis.

The incidence of Kawasaki disease using hospital admissions data for England 2006-2021 (2023)
Journal Article
Odingo, M., Rutter, M., Bowley, J., Peach, E. J., Lanyon, P. C., Grainge, M. J., …Pearce, F. A. (2023). The incidence of Kawasaki disease using hospital admissions data for England 2006-2021. Rheumatology, 62(9), 3117–3125. https://doi.org/10.1093/rheumatology/kead051

Objective: To describe the incidence of Kawasaki Disease (kDa) between 2006 and 2021 in England. Methods: We identified all cases in hospital episode statistics with an ICD-10 diagnostic code M303 (for kDa) between 1 April 2006 and 31 March 2021. We... Read More about The incidence of Kawasaki disease using hospital admissions data for England 2006-2021.

Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners (2023)
Journal Article
Chattopadhyay, K., Kapoor, N., Heinrich, M., Mitra, A., Mittal, M., Lewis, S. A., …Leonardi-Bee, J. (2023). Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners. Frontiers in Medicine, 10, Article 1043715. https://doi.org/10.3389/fmed.2023.1043715

Background: Type 2 diabetes mellitus (T2DM), a common chronic health condition, has major health and socioeconomic consequences. In the Indian subcontinent, it is a health condition for which individuals commonly consult Ayurvedic (traditional medica... Read More about Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners.

The educational value of situational judgement tests (SJTs) when used during undergraduate medical training: A systematic review and narrative synthesis (2023)
Journal Article
Sahota, G. S., Fisher, V., Patel, B., JuJ, K., & Taggar, J. S. (2023). The educational value of situational judgement tests (SJTs) when used during undergraduate medical training: A systematic review and narrative synthesis. Medical Teacher, 45(9), 997-1004. https://doi.org/10.1080/0142159x.2023.2168183

Introduction Situational judgement tests (SJTs) are a recognised assessment method for admission into medical school, selection into postgraduate training programs, and postgraduate competency assessment. More recently, however, SJTs have been used... Read More about The educational value of situational judgement tests (SJTs) when used during undergraduate medical training: A systematic review and narrative synthesis.

Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites (2023)
Journal Article
Fry, A., White, B., Nagarwalla, D., Shelton, J., & Jack, R. H. (2023). Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites. BMJ Open, 13(1), Article e062079. https://doi.org/10.1136/bmjopen-2022-062079

Objectives: Cancer stage at diagnosis is a determinant of treatment options and survival. Previous research has shown differences in barriers to presentation with cancer between ethnic groups. The completeness and quality of cancer stage and ethnicit... Read More about Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites.

Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated (2023)
Journal Article
Atallah, E., Grove, J. I., Crooks, C., Burden-Teh, E., Abhishek, A., Moreea, S., …Aithal, G. P. (2023). Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated. Journal of Hepatology, 78(5), 989-997. https://doi.org/10.1016/j.jhep.2022.12.034

Background & Aims: The risk of significant liver fibrosis from prolonged methotrexate (MTX) exposure has been estimated at around 5%, prompting intensive monitoring strategies. However, the evidence is derived from retrospective studies that under-re... Read More about Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.

Characterisation of the Paternal Influence on Intergenerational Offspring Cardiac and Brain Lipid Homeostasis in Mice (2023)
Journal Article
Furse, S., Morgan, H. L., Koulman, A., & Watkins, A. J. (2023). Characterisation of the Paternal Influence on Intergenerational Offspring Cardiac and Brain Lipid Homeostasis in Mice. International Journal of Molecular Sciences, 24(3), Article 1814. https://doi.org/10.3390/ijms24031814

There is growing evidence that poor paternal diet at the time of conception increase the risk of offspring developing a range of non-communicable metabolic diseases, such as obesity, diabetes and cardiovascular disease, in adulthood. We hypothesise t... Read More about Characterisation of the Paternal Influence on Intergenerational Offspring Cardiac and Brain Lipid Homeostasis in Mice.

The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review (2023)
Journal Article
Phillips, O., Baguley, D., Pearson, S., & Akeroyd, M. A. (2023). The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review. Journal of Cancer Survivorship, 17(1), 40-58. https://doi.org/10.1007/s11764-022-01314-9

Purpose: To elucidate the long-term impacts of hearing loss, tinnitus and balance in people living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT). Methods: A literature search was conducted between March and June 2022 u... Read More about The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review.

The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets (2023)
Journal Article
Gysling, S., Morgan, H., Ifesemen, O. S., West, D., Conibear, J., Navani, N., …Hubbard, R. (2023). The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets. Chest, 163(6), 1599-1607. https://doi.org/10.1016/j.chest.2023.01.008

Background: The COVID-19 pandemic has caused significant disruption to health-care services and delivery worldwide. The impact of the pandemic and associated national lockdowns on lung cancer incidence in England have yet to be assessed. Research Que... Read More about The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets.

A Qualitative Study of the Implementation and Continued Delivery of Complete and Partial Smoke-Free Policies Across England's Prison Estate (2023)
Journal Article
Jayes, L., Waddingham, J., Britton, J., & Murray, R. (2023). A Qualitative Study of the Implementation and Continued Delivery of Complete and Partial Smoke-Free Policies Across England's Prison Estate. Nicotine & Tobacco Research, 25(6), 1099-1108. https://doi.org/10.1093/ntr/ntac296

Introduction In the UK, smoking among prisoners is up to five times more prevalent than the national average. Between 2015 and 2018, HMPPS introduced a complete smoke-free policy in all closed prisons, and a partial policy permitting smoking only in... Read More about A Qualitative Study of the Implementation and Continued Delivery of Complete and Partial Smoke-Free Policies Across England's Prison Estate.

Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring: Part 1 wearable technology (2023)
Journal Article
Grooby, E., Sitaula, C., Chang Kwok, T., Sharkey, D., Marzbanrad, F., & Malhotra, A. (2023). Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring: Part 1 wearable technology. Pediatric Research, 93(2), 413-425. https://doi.org/10.1038/s41390-022-02416-x

Abstract: With the development of Artificial Intelligence techniques, smart health monitoring is becoming more popular. In this study, we investigate the trend of wearable sensors being adopted and developed in neonatal cardiorespiratory monitoring.... Read More about Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring: Part 1 wearable technology.

Analgesic utilization in people with knee osteoarthritis: A population-based study using primary care data (2023)
Journal Article
Taqi, A., Gran, S., & Knaggs, R. D. (2023). Analgesic utilization in people with knee osteoarthritis: A population-based study using primary care data. Pain Practice, https://doi.org/10.1111/papr.13212

Purpose: Osteoarthritis (OA) is a chronic painful condition that often affects large joints such as the knee. Treatment guidelines recommend paracetamol, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids. Antidepressants and anti-epileptic d... Read More about Analgesic utilization in people with knee osteoarthritis: A population-based study using primary care data.

Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset (2022)
Journal Article
Sisodia, S., McGill, S., Evans, M. S., Brough, G., Okereke, U., & Dunn, T. J. (2023). Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset. Public Health In Practice, 5, Article 100351. https://doi.org/10.1016/j.puhip.2022.100351

Objectives To capture and compare the differences in experiences of public health Specialty Registrars who commenced training prior to the COVID-19 pandemic (pre-pandemic Registrars) and those who commenced training during the pandemic (post-pandemi... Read More about Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset.

Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context (2022)
Journal Article
Quinn-Scoggins, H. D., Murray, R. L., Quaife, S. L., Smith, P., Brain, K. E., Callister, M. E. J., …McCutchan, G. M. (2022). Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context. BMC Pulmonary Medicine, 22(1), Article 478. https://doi.org/10.1186/s12890-022-02263-w

Background: Optimising smoking cessation services within a low radiation-dose computed tomography (LDCT) lung cancer screening programme has the potential to improve cost-effectiveness and overall efficacy of the programme. However, evidence on the o... Read More about Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context.

Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence (2022)
Journal Article
Sitaula, C., Grooby, E., Kwok, T. C., Sharkey, D., Marzbanrad, F., & Malhotra, A. (2023). Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence. Pediatric Research, 93(2), 426-436. https://doi.org/10.1038/s41390-022-02417-w

Background: With the development of Artificial Intelligence (AI) techniques, smart health monitoring, particularly neonatal cardiorespiratory monitoring with wearable devices, is becoming more popular. To this end, it is crucial to investigate the tr... Read More about Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence.

Techniques for managing an impacted fetal head at caesarean section: A systematic review (2022)
Journal Article
Peak, A. G., Barwise, E., & Walker, K. F. (2023). Techniques for managing an impacted fetal head at caesarean section: A systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 281, 12-22. https://doi.org/10.1016/j.ejogrb.2022.12.017

A complication arising at caesarean birth when the baby's head is deeply engaged in the pelvis and may be difficult to deliver, is known as an ‘impacted fetal head’. This obstetric emergency occurs in 16% of second stage caesarean sections. Multiple... Read More about Techniques for managing an impacted fetal head at caesarean section: A systematic review.

Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials (2022)
Journal Article
Santer, M., Muller, I., Becque, T., Stuart, B., Hooper, J., Steele, M., …Thomas, K. S. (2022). Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials. BMJ, 379, Article e072007. https://doi.org/10.1136/bmj-2022-072007

Objective: To determine the effectiveness of two online behavioural interventions, one for parents and carers and one for young people, to support eczema self-management. Design: Two independent, pragmatic, parallel group, unmasked, randomised contro... Read More about Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials.

'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema (2022)
Journal Article
Greenwell, K., Sivyer, K., Howells, L., Steele, M., Ridd, M. J., Roberts, A., …Muller, I. (2023). 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema. British Journal of Dermatology, 188(4), 506-513. https://doi.org/10.1093/bjd/ljac115

Background There is a lack of well-conducted randomized controlled trials evaluating the effectiveness of theory-based online interventions for eczema. To address these deficiencies, we previously developed and demonstrated the effectiveness of two o... Read More about 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema.