All Outputs (82)

The majority of observational studies in leading peer-reviewed medicine journals are not registered and do not have a publicly accessible protocol: a scoping review (2024)
Journal Article

Objectives Observational studies are not subject to the same requirements as randomized controlled trials, such as registration or publishing a protocol. The aim of this scoping review was to estimate the registration rate of observational studies i... Read More about The majority of observational studies in leading peer-reviewed medicine journals are not registered and do not have a publicly accessible protocol: a scoping review.

The majority of observational studies in leading peer-reviewed medicine journals are not registered and do not have a publicly accessible protocol: a scoping review (2024)
Journal Article

Objectives Observational studies are not subject to the same requirements as randomized controlled trials, such as registration or publishing a protocol. The aim of this scoping review was to estimate the registration rate of observational studies i... Read More about The majority of observational studies in leading peer-reviewed medicine journals are not registered and do not have a publicly accessible protocol: a scoping review.

Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention (2024)
Journal Article

Many pregnant smokers need support to quit successfully. In the United Kingdom, trained smoking cessation advisors deliver structured behavioural counselling alongside access to free nicotine replacement therapy (NRT); known as the ‘Standard Treatmen... Read More about Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention.

Behaviour support in dentistry: A Delphi study to agree terminology in behaviour management (2024)
Journal Article

Objectives: Dental behaviour support (DBS) describes all specific techniques practiced to support patients in their experience of professional oral healthcare. DBS is roughly synonymous with behaviour management, which is an outdated concept. There i... Read More about Behaviour support in dentistry: A Delphi study to agree terminology in behaviour management.

Potential smoke-free dividend across local areas in England: A cross-sectional analysis (2024)
Journal Article

Background The value that might be added to local economies each year through the money that people who smoke tobacco would save if everyone quit smoking is called the “smoke-free dividend”. This study aimed to estimate the value of the smoke-free d... Read More about Potential smoke-free dividend across local areas in England: A cross-sectional analysis.

Substantial cost savings of ultrasound-based management over magnetic resonance imaging-based management in an inflammatory bowel disease service (2024)
Journal Article

Background: Imaging is used to monitor disease activity in small bowel Crohn’s disease (CD). Magnetic Resonance Enterography is often employed as a first modality in the United Kingdom for assessment and monitoring; however, waiting times, cost, pati... Read More about Substantial cost savings of ultrasound-based management over magnetic resonance imaging-based management in an inflammatory bowel disease service.

Prevalence, regional patterns and socio-demographic factors associated with poly-tobacco use in India: A secondary data analysis (2024)
Journal Article

Background: Tobacco use is associated with early, intermediate and long-term complications throughout the life course. With an influx of newer products containing nicotine, poly-tobacco use is slowly emerging as a public health concern, that is defin... Read More about Prevalence, regional patterns and socio-demographic factors associated with poly-tobacco use in India: A secondary data analysis.

Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases (2024)
Journal Article

Objective To explore the acceptability of an individualised risk-stratified approach to monitoring for target-organ toxicity in adult patients with immune-mediated inflammatory diseases established on immune-suppressing treatment(s). Methods Adu... Read More about Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases.

Uptake and safety of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide observational study (2024)
Journal Article

Objective The uptake and safety of pneumococcal vaccination in people with immune mediated inflammatory diseases (IMIDs) is poorly understood. We investigated the UK wide pneumococcal vaccine uptake in adults with IMIDs and explored the association b... Read More about Uptake and safety of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide observational study.

Formative work for the LEGEND (Low EnerGy DiEt iN adolescents with type 2 diabetes and obesity) study: a worked example of patient and public involvement in research (2024)
Journal Article

This study uses evidence-based guidance to report on patient and public involvement and engagement activity that informed the design of a feasibility trial to explore the use of low energy diet for children and young people with type 2 diabetes. Over... Read More about Formative work for the LEGEND (Low EnerGy DiEt iN adolescents with type 2 diabetes and obesity) study: a worked example of patient and public involvement in research.

Ethnicity and socio-economic status affects the incidence and survival of hepatosplenic T-cell lymphoma (2024)
Journal Article

To address the lack of contemporary population-based epidemiological studies of hepatosplenic T-cell lymphoma (HSTCL), we undertook a population-based study of ICD-O-3-coded HSTCL in England. We used the National Cancer Registration Dataset and linke... Read More about Ethnicity and socio-economic status affects the incidence and survival of hepatosplenic T-cell lymphoma.

Commentary: A comparative randomized clinical trial evaluating the efficacy and safety of tacrolimus versus hydrocortisone as a topical treatment of atopic dermatitis in children (2024)
Journal Article

REMOTE-ILD study: Description of the protocol for a multicentre, 12-month randomised controlled trial to assess the clinical and cost-effectiveness of remote monitoring of spirometry and pulse oximetry in patients with interstitial lung disease (2024)
Journal Article

Introduction Remote monitoring of home physiological measurements has been proposed as a solution to support patients with chronic diseases as well as facilitating virtual consultations and pandemic preparedness for the future. Daily home spirometry... Read More about REMOTE-ILD study: Description of the protocol for a multicentre, 12-month randomised controlled trial to assess the clinical and cost-effectiveness of remote monitoring of spirometry and pulse oximetry in patients with interstitial lung disease.

Effectiveness and safety of self-management interventions for improving glycemic control and health-related quality-of-life among adults with type 2 diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis (2024)
Journal Article

Objective: To assess and synthesize evidence on the effectiveness and safety of self- management interventions for improving glycemic control and health-related quality-of-life (HRQoL) among adults with type 2 diabetes mellitus (T2DM) in sub-Saha... Read More about Effectiveness and safety of self-management interventions for improving glycemic control and health-related quality-of-life among adults with type 2 diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis.

Evaluation of Pathway to Diagnosis of Pediatric Brain Tumors in Tamil Nadu, India (2024)
Journal Article

Purpose Delayed diagnosis and poor awareness are significant barriers to the early intervention of pediatric brain tumors. This multicenter observational study aimed to evaluate the baseline routes and time to diagnosis for pediatric brain tumors in... Read More about Evaluation of Pathway to Diagnosis of Pediatric Brain Tumors in Tamil Nadu, India.

The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action (2024)
Journal Article

Introduction Digital cessation support appeals to pregnant smokers. In two pooled RCTs, MiQuit, a pregnancy-specific tailored text messaging intervention, did not show effectiveness for validated prolonged abstinence. However, secondary outcomes and... Read More about The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action.

The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study (2024)
Journal Article

Background: Social isolation is a potentially reversible risk factor for suicide. Methods: A matched case control study design was used. The study population was from England and identified from an electronic primary case database with linkage to a s... Read More about The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study.

Primary care consultation patterns prior to suicide: a nationally representative case-control study. (2024)
Journal Article

Consultation with primary health care may provide an opportunity to identify patients at higher suicide risk. To explore primary care consultation patterns in the 5 years before suicide to identify suicide high-risk groups and common reasons for cons... Read More about Primary care consultation patterns prior to suicide: a nationally representative case-control study..

Motivation communication training programme for healthcare professionals to support adherence in patients with diabetic foot ulcers: Proof of concept study (2024)
Journal Article

Patients with diabetic foot ulcers have poor adherence to treatment recommendations. However, the most effective way to support adherence in this population is unknown. This study aimed to assess the preliminary effectiveness of a motivation communic... Read More about Motivation communication training programme for healthcare professionals to support adherence in patients with diabetic foot ulcers: Proof of concept study.

Effectiveness and safety of COVID-19 vaccination in people with blood cancer (2024)
Journal Article

Background People with blood cancer have increased risk of severe COVID-19 outcomes and poor response to vaccination. We assessed the safety and effectiveness of COVID-19 vaccines in this vulnerable group compared to the general population. Methods... Read More about Effectiveness and safety of COVID-19 vaccination in people with blood cancer.