Community pharmacy perspectives on managing skin conditions: Mixed methods online survey
(2023)
Journal Article
All Outputs (323)
Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY (2023)
Journal Article
Background: In the UK, additional COVID-19 vaccine booster doses and treatments are offered to people who are immunosuppressed to protect against severe COVID-19, but how best to choose the individuals that receive these vaccine booster doses and tre... Read More about Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY.
Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy (2023)
Journal Article
Background Some pregnant smokers try e-cigarettes, but effectiveness and safety of such use are unknown. Objectives To compare effectiveness and safety of nicotine patches and e-cigarettes in pregnancy. Design A pragmatic multi-centre random... Read More about Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy.
Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’ (2023)
Journal Article
In 2018, the World Health Organization declared childhood cancer as a global disease burden, launching a Global Initiative to improve survival to 60% worldwide by 2030. If achieved, it is estimated that an extra 1 million children’s lives will be sav... Read More about Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’.
Managing raised ferritin in primary care (2023)
Journal Article
Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England (2023)
Journal Article
Background: Analgesics prescriptions may provide a marker for identifying individuals at higher risk of suicide. In particular, awareness of which analgesics are implicated may help clinicians assess and modify risk. Method: A case–control study in E... Read More about Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England.
Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review (2023)
Journal Article
Social determinants of health significantly impact population health status. The aim of this systematic review was to examine which social vulnerability factors or determinants of health at the individual or county level affected vaccine uptake withi... Read More about Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review.
Frequency and impact of medication reviews for people aged 65 years or above in UK primary care: an observational study using electronic health records (2023)
Journal Article
Background Medication reviews in primary care provide an opportunity to review and discuss the safety and appropriateness of a person’s medicines. However, there is limited evidence about access to and the impact of routine medication reviews for old... Read More about Frequency and impact of medication reviews for people aged 65 years or above in UK primary care: an observational study using electronic health records.
Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) (2023)
Journal Article
Purpose To investigate the longitudinal associations between pain and depressive symptoms in adults. Methods Prospective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follo... Read More about Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).
How frequent is routine use of probiotics in UK neonatal units? (2023)
Journal Article
Objective There is a lack of UK guidance regarding routine use of probiotics in preterm infants to prevent necrotising enterocolitis, late-onset sepsis and death. As practices can vary, we aimed to determine the current usage of probiotics within neo... Read More about How frequent is routine use of probiotics in UK neonatal units?.
Implementation of the HOME core outcome set for clinical trials of atopic eczema—barriers and opportunities: the HOME IX meeting report (2023)
Journal Article
The Harmonising Outcome Measures for Eczema (HOME) initiative established a core outcome set (COS) for atopic eczema (AE) clinical trials in 2019. This set encompasses four core outcome domains and corresponding measurement instruments: clinical sign... Read More about Implementation of the HOME core outcome set for clinical trials of atopic eczema—barriers and opportunities: the HOME IX meeting report.
Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database. (2023)
Journal Article
Background The burden of osteoarthritis (OA) in UK primary care has not been investigated thoroughly. Aim To estimate healthcare use and mortality in people with OA (overall and joint specific). Design and setting A matched cohort study of adul... Read More about Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database..
UK research data resources based on primary care electronic health records: review and summary for potential users (2023)
Journal Article
Objectives To describe the current landscape of UK electronic health record (EHR) databases and considerations of access and use of these resources relevant to researchers. Design & setting Narrative review Data sources Information was collecte... Read More about UK research data resources based on primary care electronic health records: review and summary for potential users.
Understanding colorectal cancer risk for symptomatic patients in primary care: A cohort study utilising faecal immunochemical tests and blood results in England (2023)
Journal Article
Background: A faecal immunochemical tests (FIT) cut-off of ≥10 μg Hb/g faeces is now recommended in the UK as a gateway to urgent (suspected cancer) investigation for colorectal cancer (CRC), based on an expected CRC risk threshold of 3%. Aims: To qu... Read More about Understanding colorectal cancer risk for symptomatic patients in primary care: A cohort study utilising faecal immunochemical tests and blood results in England.
Systematic review and meta‐analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy (2023)
Journal Article
Aims: To determine effects of concurrent smoking and nicotine replacement therapy (NRT) use on reported heaviness of smoking, nicotine (cotinine) body fluid and exhaled air carbon monoxide (CO) concentrations. Methods: Systematic review and meta‐anal... Read More about Systematic review and meta‐analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy.
Systematic review and meta-analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy (2023)
Journal Article
Aims To determine effects of concurrent smoking and nicotine replacement therapy (NRT) use on reported heaviness of smoking, nicotine (cotinine) body fluid and exhaled air carbon monoxide (CO) concentrations. Methods Systematic review and meta-a... Read More about Systematic review and meta-analysis investigating nicotine, cotinine and carbon monoxide exposures in people who both smoke and use nicotine replacement therapy.
Respiratory rate responses to both hypercapnia and acidaemia are modified by age in patients with acidosis (2023)
Journal Article
Objective To explore the associations between arterial pO2, pCO2 and pH and how these are modified by age. Methods An analysis of 2598 patients admitted with a diagnosis of Covid-19 infection to a large UK teaching hospital. Results There we... Read More about Respiratory rate responses to both hypercapnia and acidaemia are modified by age in patients with acidosis.
Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD): an open-label pragmatic feasibility randomised controlled trial (2023)
Journal Article
Background: Early identification followed by effective behaviour interventions is pivotal to changing the natural history of alcohol-related liver disease. We examined the feasibility of using transient elastography based advice and alcohol recovery... Read More about Does knowledge of liver fibrosis affect high-risk drinking behaviour (KLIFAD): an open-label pragmatic feasibility randomised controlled trial.