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All Outputs (28)

Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset (2022)
Journal Article
Sisodia, S., McGill, S., Evans, M. S., Brough, G., Okereke, U., & Dunn, T. J. (2023). Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset. Public Health In Practice, 5, Article 100351. https://doi.org/10.1016/j.puhip.2022.100351

Objectives To capture and compare the differences in experiences of public health Specialty Registrars who commenced training prior to the COVID-19 pandemic (pre-pandemic Registrars) and those who commenced training during the pandemic (post-pandemi... Read More about Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset.

Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context (2022)
Journal Article
Quinn-Scoggins, H. D., Murray, R. L., Quaife, S. L., Smith, P., Brain, K. E., Callister, M. E. J., …McCutchan, G. M. (2022). Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context. BMC Pulmonary Medicine, 22(1), Article 478. https://doi.org/10.1186/s12890-022-02263-w

Background: Optimising smoking cessation services within a low radiation-dose computed tomography (LDCT) lung cancer screening programme has the potential to improve cost-effectiveness and overall efficacy of the programme. However, evidence on the o... Read More about Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context.

Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence (2022)
Journal Article
Sitaula, C., Grooby, E., Kwok, T. C., Sharkey, D., Marzbanrad, F., & Malhotra, A. (2023). Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence. Pediatric Research, 93(2), 426-436. https://doi.org/10.1038/s41390-022-02417-w

Background: With the development of Artificial Intelligence (AI) techniques, smart health monitoring, particularly neonatal cardiorespiratory monitoring with wearable devices, is becoming more popular. To this end, it is crucial to investigate the tr... Read More about Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence.

Techniques for managing an impacted fetal head at caesarean section: A systematic review (2022)
Journal Article
Peak, A. G., Barwise, E., & Walker, K. F. (2023). Techniques for managing an impacted fetal head at caesarean section: A systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 281, 12-22. https://doi.org/10.1016/j.ejogrb.2022.12.017

A complication arising at caesarean birth when the baby's head is deeply engaged in the pelvis and may be difficult to deliver, is known as an ‘impacted fetal head’. This obstetric emergency occurs in 16% of second stage caesarean sections. Multiple... Read More about Techniques for managing an impacted fetal head at caesarean section: A systematic review.

'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema (2022)
Journal Article
Greenwell, K., Sivyer, K., Howells, L., Steele, M., Ridd, M. J., Roberts, A., …Muller, I. (2023). 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema. British Journal of Dermatology, 188(4), 506-513. https://doi.org/10.1093/bjd/ljac115

Background There is a lack of well-conducted randomized controlled trials evaluating the effectiveness of theory-based online interventions for eczema. To address these deficiencies, we previously developed and demonstrated the effectiveness of two o... Read More about 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema.

Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials (2022)
Journal Article
Santer, M., Muller, I., Becque, T., Stuart, B., Hooper, J., Steele, M., …Thomas, K. S. (2022). Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials. BMJ, 379, Article e072007. https://doi.org/10.1136/bmj-2022-072007

Objective: To determine the effectiveness of two online behavioural interventions, one for parents and carers and one for young people, to support eczema self-management. Design: Two independent, pragmatic, parallel group, unmasked, randomised contro... Read More about Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials.

Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial (2022)
Journal Article
Bradshaw, L. E., Wyatt, L. A., Brown, S. J., Haines, R. H., Montgomery, A. A., Perkin, M. R., …Williams, H. C. (2023). Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial. Allergy, 78(4), 995-1006. https://doi.org/10.1111/all.15555

Background: The effectiveness of emollients for preventing atopic dermatitis/eczema is controversial. The Barrier Enhancement for Eczema Prevention trial evaluated the effects of daily emollients during the first year of life on atopic dermatitis and... Read More about Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial.

The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum (2022)
Journal Article
Rick, J., Gould, L. J., Marzano, A. V., Garg, A., Chen, D., Oakes, D. L., …Ortega-Loayza, A. G. (2023). The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum. Archives of Dermatological Research, 315(4), 983-988. https://doi.org/10.1007/s00403-022-02424-1

Introduction: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that affects approximately 0.3–6 out of every 100,000 people worldwide. Clinical trials are scarce but there is growing interest in using newer and more targeted therapeutics t... Read More about The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum.

Effects of mobile technology-based interventions for promoting mental health and psychosocial well-being among young people in low- and middle-income countries: a systematic review protocol (2022)
Journal Article
Rai, D., Bhattacharjee, S., Dhakal, R., Chattopadhyay, K., & Neupane, D. (2023). Effects of mobile technology-based interventions for promoting mental health and psychosocial well-being among young people in low- and middle-income countries: a systematic review protocol. JBI Evidence Synthesis, 21(4), 744-752. https://doi.org/10.11124/JBIES-22-00034

Objective: This review will aim to examine the effectiveness of mobile-based technologies implemented in low-and middle-income countries (LMICs) among young people (10-24 years) to promote their mental health and psychosocial wellbeing. Such promotio... Read More about Effects of mobile technology-based interventions for promoting mental health and psychosocial well-being among young people in low- and middle-income countries: a systematic review protocol.

Risk of Suicide After Dementia Diagnosis (2022)
Journal Article
Alothman, D., Card, T., Lewis, S., Tyrrell, E., Fogarty, A. W., & Marshall, C. R. (2022). Risk of Suicide After Dementia Diagnosis. JAMA Neurology, 79(11), 1148-1154. https://doi.org/10.1001/jamaneurol.2022.3094

Importance: Patients with dementia may be at an increased suicide risk. Identifying groups at greatest risk of suicide would support targeted risk reduction efforts by clinical dementia services. Objectives: To examine the association between a d... Read More about Risk of Suicide After Dementia Diagnosis.

Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis (2022)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Nguyen Van-Tam, J. S., Williams, H. C., & Abhishek, A. (2023). Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis. Rheumatology, 62(4), 1445-1450. https://doi.org/10.1093/rheumatology/keac484

OBJECTIVES: To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and autoimmune rheumatic disease (AIRD) flare. MATERIAL AND METHODS: Patients with AIRDs vaccinated against COVID-19 who consulted for dise... Read More about Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis.

Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model (2022)
Journal Article
Walker, K. F., Zaher, S., Torrejon Torres, R., Saunders, S. J., Saunders, R., & Gupta, J. K. (2022). Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model. European Journal of Obstetrics and Gynecology and Reproductive Biology, 278, 72-76. https://doi.org/10.1016/j.ejogrb.2022.08.018

To estimate the costs of synthetic osmotic dilators (Dilapan-S) compared to dinoprostone vaginal inserts (Propess) for inpatient induction of labour (IOL). A population-level, Markov model-based cost-consequence analysis was developed to compare the... Read More about Synthetic osmotic dilators (Dilapan-S) or dinoprostone vaginal inserts (Propess) for inpatient induction of labour: A UK cost-consequence model.

Caring for women experiencing miscarriage and the importance of good communication (2022)
Journal Article
Hart, S., & Walker, K. F. (2022). Caring for women experiencing miscarriage and the importance of good communication. Obstetrics, Gynaecology and Reproductive Medicine, 32(11), 262-263. https://doi.org/10.1016/j.ogrm.2022.08.009

The importance of good quality nursing care for pregnancy loss patients can not be underestimated. Pregnancy loss is comparable to any other kind of loss and patients have noted that the nursing care they receive while in hospital can either add to o... Read More about Caring for women experiencing miscarriage and the importance of good communication.

Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice (2022)
Journal Article
Morgan, H. L., Furse, S., Dias, I. H. K., Shabir, K., Castellanos, M., Khan, I., …Watkins, A. J. (2022). Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice. Communications Biology, 5(1), Article 929. https://doi.org/10.1038/s42003-022-03914-8

The underlying mechanisms driving paternally-programmed metabolic disease in offspring remain poorly defined. We fed male C57BL/6 mice either a control normal protein diet (NPD; 18% protein) or an isocaloric low protein diet (LPD; 9% protein) for a m... Read More about Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice.

The Exeter Activity Unlimited statement on physical activity and exercise for cystic fibrosis: methodology and results of an international, multidisciplinary, evidence-driven expert consensus (2022)
Journal Article
Williams, C., Barker, A. R., Denford, S., Van Beurden, S. B., Bianchim, M. S., Caterini, J. E., …Tomlinson, O. W. (2022). The Exeter Activity Unlimited statement on physical activity and exercise for cystic fibrosis: methodology and results of an international, multidisciplinary, evidence-driven expert consensus. Chronic Respiratory Disease, 19, https://doi.org/10.1177/14799731221121670

Background The roles of physical activity (PA) and exercise within the management of cystic fibrosis (CF) are recognised by their inclusion in numerous standards of care and treatment guidelines. However, information is brief, and both PA and exerci... Read More about The Exeter Activity Unlimited statement on physical activity and exercise for cystic fibrosis: methodology and results of an international, multidisciplinary, evidence-driven expert consensus.

Identifying Patients with Bicuspid Aortic Valve Disease in UK Primary Care: A Case–Control Study and Prediction Model (2022)
Journal Article
Evans, W., Akyea, R. K., Weng, S., Kai, J., & Qureshi, N. (2022). Identifying Patients with Bicuspid Aortic Valve Disease in UK Primary Care: A Case–Control Study and Prediction Model. Journal of Personalized Medicine, 12(8), Article 1290. https://doi.org/10.3390/jpm12081290

Bicuspid aortic valve disease (BAV) is the most common congenital heart condition, and early detection can improve outcomes for patients. In this case–control study, patients with a diagnosis of BAV were identified from their electronic primary-care... Read More about Identifying Patients with Bicuspid Aortic Valve Disease in UK Primary Care: A Case–Control Study and Prediction Model.

Measuring the Impact of the COVID-19 Pandemic on Diagnostic Delay in Rare Disease (2022)
Journal Article
Hampson, C., Evans, W., McKay, L., & Menzies, L. (2022). Measuring the Impact of the COVID-19 Pandemic on Diagnostic Delay in Rare Disease. EMJ Innovations, https://doi.org/10.33590/emj/21-00181

Rare diseases are individually rare but collectively common, with a combined prevalence of 3.5–5.9%. A common feature of many diseases is a substantial delay in patients receiving a correct diagnosis; this protracted path to diagnosis is termed ‘the... Read More about Measuring the Impact of the COVID-19 Pandemic on Diagnostic Delay in Rare Disease.

Systems and Processes that Enable Progress for Older Forensic Mental Health Patients (2022)
Journal Article
Walker, K., Furtado, V., Yates, J., Dening, T., Völlm, B., & Griffiths, C. (2023). Systems and Processes that Enable Progress for Older Forensic Mental Health Patients. International Journal of Forensic Mental Health, 22(2), 93-104. https://doi.org/10.1080/14999013.2022.2080304

Older forensic mental health patients have complex needs and requirements; service provision is required to address mental health, offending risk and issues associated with aging (geriatric care). This study aimed to identify the systems and processe... Read More about Systems and Processes that Enable Progress for Older Forensic Mental Health Patients.

Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice? (2022)
Journal Article
Ojha, S., Abramson, J., & Dorling, J. (2022). Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?. BMJ Paediatrics Open, 6(1), Article e001460. https://doi.org/10.1136/bmjpo-2022-001460

Mechanical ventilation is an uncomfortable and potentially painful intervention. Opioids, such as morphine and fentanyl, are used for analgesia and sedation but there is uncertainty whether they reduce pain in mechanically ventilated infants. Moreove... Read More about Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?.