Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study

Swain, S.; Coupland, C.; Strauss, V.; Mallen, C.; Kuo, C. F.; Sarmanova, A.; Bierma-Zeinstra, S. M.A.; Englund, M.; Prieto-Alhambra, D.; Doherty, M.; Zhang, W.

doi:10.1016/j.joca.2021.12.013

International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia (2022)
Journal Article
Kundakci, B., Hall, M., Atzeni, F., Branco, J. C., Buskila, D., Clauw, D., …Taylor, A. M. (2022). International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia. Seminars in Arthritis and Rheumatism, 57, Article 152101. https://doi.org/10.1016/j.semarthrit.2022.152101

Objectives: To develop evidence-based expert recommendations for non-pharmacological treatments for pain, fatigue, sleep problems, and depression in fibromyalgia. Methods: An international, multidisciplinary Delphi exercise was conducted. Authors of... Read More about International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia.

Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis (2022)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Nguyen Van-Tam, J. S., Williams, H. C., & Abhishek, A. (2023). Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis. Rheumatology, 62(4), 1445-1450. https://doi.org/10.1093/rheumatology/keac484

OBJECTIVES: To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and autoimmune rheumatic disease (AIRD) flare. MATERIAL AND METHODS: Patients with AIRDs vaccinated against COVID-19 who consulted for dise... Read More about Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis.

Does covid-19 impair endogenous neurogenesis? (2022)
Journal Article
Kumaria, A., Noah, A., & Kirkman, M. A. (2022). Does covid-19 impair endogenous neurogenesis?. Journal of Clinical Neuroscience, 105, 79-85. https://doi.org/10.1016/j.jocn.2022.09.006

Endogenous neural stem cells are thought to continue to generate new neurons throughout life in the human brain. Endogenous neurogenesis has been proposed to contribute to physiological roles in maintaining and regenerating olfaction, as well as prom... Read More about Does covid-19 impair endogenous neurogenesis?.

Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions (2022)
Journal Article
Gibbons, S. M., Gurry, T., Lampe, J. W., Chakrabarti, A., Dam, V., Everard, A., …Miani, M. (2022). Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions. Advances in Nutrition, 13(5), 1450-1461. https://doi.org/10.1093/advances/nmac075

Humans often show variable responses to dietary, prebiotic, and probiotic interventions. Emerging evidence indicates that the gut microbiota is a key determinant for this population heterogeneity. Here, we provide an overview of some of the major com... Read More about Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions.

Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study (2022)
Journal Article
Ellis, R., Laviola, M., Stolady, D., Valentine, R. L., Pillai, A., & Hardman, J. G. (2022). Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study. British Journal of Anaesthesia, 129(4), 581-587. https://doi.org/10.1016/j.bja.2022.06.021

Background: Hypoxaemia during general anaesthesia can cause harm. Apnoeic oxygenation extends safe apnoea time, reducing risk during airway management. We hypothesised that low-flow nasal oxygenation (LFNO) would extend safe apnoea time similarly to... Read More about Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study.

Risk of Comorbidities Following Physician‐Diagnosed Knee or Hip Osteoarthritis: A Register‐Based Cohort Study (2022)
Journal Article
Dell'Isola, A., Pihl, K., Turkiewicz, A., Hughes, V., Zhang, W., Bierma-Zeinstra, S., …Englund, M. (2022). Risk of Comorbidities Following Physician‐Diagnosed Knee or Hip Osteoarthritis: A Register‐Based Cohort Study. Arthritis Care and Research, 74(10), 1689-1695. https://doi.org/10.1002/acr.24717

Objective: To estimate the risk of developing comorbidities in patients after physician-diagnosed knee or hip osteoarthritis (OA). Methods: This was a cohort study using Swedish longitudinal health care register data; we studied residents in the Skån... Read More about Risk of Comorbidities Following Physician‐Diagnosed Knee or Hip Osteoarthritis: A Register‐Based Cohort Study.

AB1432 THE ASSOCIATION OF PAINFUL AND NON-PAINFUL COMORBIDITIES WITH CENTRAL MECHANISMS OF KNEE PAIN (2022)
Journal Article
Lewis, H., Chaplin, W., Mcwilliams, D., Millar, B., Shahtaheri, S., Gladman, J., & Walsh, D. (2022). AB1432 THE ASSOCIATION OF PAINFUL AND NON-PAINFUL COMORBIDITIES WITH CENTRAL MECHANISMS OF KNEE PAIN. Annals of the Rheumatic Diseases, 81(Suppl 1), 1822. https://doi.org/10.1136/annrheumdis-2022-eular.1586

Gut dysbiosis in rheumatic diseases: A systematic review and meta-analysis of 92 observational studies (2022)
Journal Article
Wang, Y., Wei, J., Zhang, W., Doherty, M., Zhang, Y., Xie, H., …Zeng, C. (2022). Gut dysbiosis in rheumatic diseases: A systematic review and meta-analysis of 92 observational studies. EBioMedicine, 80, Article 104055. https://doi.org/10.1016/j.ebiom.2022.104055

Background: Emerging evidence suggests that dysbiosis in gut microbiota may contribute to the occurrence or development of several rheumatic diseases. Since gut microbiota dysbiosis is potentially modifiable, it has been postulated to be a promising... Read More about Gut dysbiosis in rheumatic diseases: A systematic review and meta-analysis of 92 observational studies.

CAN CONTINUOUS KNEE PAIN OUTCOME MEASURES BE HARMONISED? (2022)
Journal Article
Georgopoulos, V., Perry, T., Smith, S., McWilliams, D., Gohir, S., Valdes, A., …Walsh, D. (2022). CAN CONTINUOUS KNEE PAIN OUTCOME MEASURES BE HARMONISED?. Osteoarthritis and Cartilage, 30(Supp 1), S15-S17. https://doi.org/10.1016/J.JOCA.2022.02.011

RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA (2022)
Journal Article
Dixon, J., Thi Mai, T., McLaren, J., Ollivere, B., Scammell, B., & Eltaher, H. (2022). RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA. Tissue Engineering: Parts A, B, and C, 28(S1),

Survivors with severe tissue injury have unmet clinical needs for better bone and soft tissue regeneration. Specifically they have progressive tissue loss due to inflammation, necrosis, infection and the development of critical size bone defects is a... Read More about RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA.

Sustaining interventions in care homes initiated by quality improvement projects: a qualitative study (2022)
Journal Article
Devi, R., Martin, G. P., Banerjee, J., Gladman, J. R., Dening, T., Barat, A., & Gordon, A. L. (2022). Sustaining interventions in care homes initiated by quality improvement projects: a qualitative study. BMJ Quality and Safety, 32(11), 665-675. https://doi.org/10.1136/bmjqs-2021-014345

Introduction: Inadequate and varied quality of care in care homes has led to a proliferation of quality improvement (QI) projects. This study examined the sustainability of interventions initiated by such projects. Method: This qualitative study expl... Read More about Sustaining interventions in care homes initiated by quality improvement projects: a qualitative study.

A comparative analysis of multidimensional computerized adaptive testing for the DASH and QuickDASH scores in Dupuytren’s disease (2022)
Journal Article
Harrison, C., Clelland, A. D., Davis, T. R., Scammell, B. E., Zhang, W., Russell, P., …Rodrigues, J. (2022). A comparative analysis of multidimensional computerized adaptive testing for the DASH and QuickDASH scores in Dupuytren’s disease. Journal of Hand Surgery (European Volume), 47(7), 750-754. https://doi.org/10.1177/17531934221081803

The QuickDASH is a short-form version of the DASH questionnaire, the most widely used patient-reported outcome measure in hand surgery. Multidimensional computerized adaptive testing (MCAT) can produce shorter and more precise testing than static sho... Read More about A comparative analysis of multidimensional computerized adaptive testing for the DASH and QuickDASH scores in Dupuytren’s disease.

Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study (2022)
Journal Article
Swain, S., Coupland, C., Strauss, V., Mallen, C., Kuo, C. F., Sarmanova, A., …Zhang, W. (2022). Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study. Osteoarthritis and Cartilage, 30(5), 702-713. https://doi.org/10.1016/j.joca.2021.12.013

Objective: To examine the clusters of chronic conditions present in people with osteoarthritis and the associated risk factors and health outcomes. Methods: Clinical Practice Research Datalink (CPRD) GOLD was used to identify people diagnosed with in... Read More about Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study.

All Outputs (13)