All Outputs (176)

Occupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study (2020)
Journal Article

Background Hip and knee replacements are regularly performed for patients who work. There is little evidence about these patients’ needs and the factors influencing their return to work. There is a paucity of guidance to help patients return to wor... Read More about Occupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study.

Corrigendum to: Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study (2020)
Journal Article

Effect of vitamin D supplementation on pain and physical function in patients with knee osteoarthritis (OA): an OA Trial Bank protocol for a systematic review and individual patient data (IPD) meta-analysis (2020)
Journal Article

Introduction: Observational data suggest that vitamin D deficiency is associated with the onset and progression of knee osteoarthritis (OA). However, randomised controlled trials (RCTs) to date investigating the efficacy of vitamin D supplementation... Read More about Effect of vitamin D supplementation on pain and physical function in patients with knee osteoarthritis (OA): an OA Trial Bank protocol for a systematic review and individual patient data (IPD) meta-analysis.

Anomia in people with rapidly evolving severe relapsing-remitting multiple sclerosis: both word retrieval inaccuracy and delay are common symptoms (2019)
Journal Article

Background: Multiple Sclerosis (MS) is a neurodegenerative disease that produces plaques throughout the central nervous system. MS can present in four different clinical courses. Of these, Relapsing-Remitting MS (RRMS) is the main clinical course, es... Read More about Anomia in people with rapidly evolving severe relapsing-remitting multiple sclerosis: both word retrieval inaccuracy and delay are common symptoms.

CGRP and painful pathologies other than headache (2019)
Book Chapter

© 2019, Springer Nature Switzerland AG. CGRP has long been suspected as a mediator of arthritis pain, although evidence that CGRP directly mediates human musculoskeletal pain remains circumstantial. This chapter describes in depth the evidence surrou... Read More about CGRP and painful pathologies other than headache.

Comment on: Temporal relationships between systemic lupus erythematosus and comorbidities: reply (2019)
Journal Article

Do maladaptive beliefs delay whiplash associated disorders (WAD): A systematic review (2018)
Journal Article

The purpose of the study is to try to establish if maladaptive beliefs effect recovery times and poor outcomes in whiplash associated disorders (WAD). In May 2017 the following databases were searched from their inception until June 2017: SPORT Discu... Read More about Do maladaptive beliefs delay whiplash associated disorders (WAD): A systematic review.

Clinical prediction rules in the prognosis of whiplash associated disorders: A systematic review (2017)
Journal Article

Clinical prediction rules in the prognosis of Whiplash Associated Disorder (WAD): A systematic review (2016)
Journal Article

Objectives: To identify, evaluate and ascertain the clinical readiness of prognostic Clinical Prediction Rules (CPRs) in the prognosis of Whiplash Associated Disorder (WAD). Study design: Systematic review Background: The scientific basis for m... Read More about Clinical prediction rules in the prognosis of Whiplash Associated Disorder (WAD): A systematic review.

Mechanisms, impact and management of pain in rheumatoid arthritis (2014)
Journal Article

© 2014 Macmillan Publishers Limited. All rights reserved. People with rheumatoid arthritis (RA) identify pain as their most important symptom, one that often persists despite optimal control of inflammatory disease. RA pain arises from multiple mecha... Read More about Mechanisms, impact and management of pain in rheumatoid arthritis.

Pain in rheumatoid arthritis (2012)
Journal Article

Rheumatoid arthritis (RA) is an inflammatory disease of synovial joints, and pain is the predominant problem for people with RA. Pain in RA is distressing in its own right and adversely affects disability and psychosocial outcomes. RA pain may be due... Read More about Pain in rheumatoid arthritis.

Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS): Study protocol for a randomised controlled trial (2011)
Journal Article

Background Many older people presenting to Acute Medical Units (AMU) are discharged after only a short stay (< 72 hours), yet many re-present to hospital or die within 1 year. Comprehensive Geriatric Assessment may improve patient outcomes for this... Read More about Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS): Study protocol for a randomised controlled trial.

Inflammation and angiogenesis in osteoarthritis (2003)
Journal Article

Objective. To quantify the relationship between inflammation and angiogenesis in synovial tissue from patients with osteoarthritis (OA). Methods. Hematoxylin and eosin staining and histologic grading for inflammation were performed for 104 patients w... Read More about Inflammation and angiogenesis in osteoarthritis.

Genetic modification of cell lines to enhance their metastatic capability (2001)
Book Chapter

Antibodies raised against the extracellular tail of the CCKB/gastrin receptor inhibit gastrin-stimulated signalling (2001)
Journal Article

Introduction: Gastrin acts to stimulate gastric acid secretion and is an acknowledged growth factor for human gastrointestinal (GI) cancer. The identity of the exact receptor type mediating the growth promoting effects of gastrin in tumours is uncert... Read More about Antibodies raised against the extracellular tail of the CCKB/gastrin receptor inhibit gastrin-stimulated signalling.

Coexpression of gastrin and gastrin receptors (CCK-B and ΔCCK-B) in gastrointestinal tumour cell lines (1998)
Journal Article

Background - The peptide hormone gastrin is a recognised growth factor for gastrointestinal (GI) tumour cells. Carboxyamidated gastrins bind to the cell surface gastrin/cholecystokinin B (CCK-B) receptor which can be expressed as either a normal or a... Read More about Coexpression of gastrin and gastrin receptors (CCK-B and ΔCCK-B) in gastrointestinal tumour cell lines.