All Outputs (161)

An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs (2023)
Journal Article

Antipsychotic medications are widely prescribed in psychotic illnesses and other mental disorders. Effectiveness is well-established, particularly for reducing symptoms such as delusions and hallucinations, but can be impacted by tolerability. Advers... Read More about An umbrella review of adverse effects associated with antipsychotic medications: the need for complementary study designs.

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data (2023)
Journal Article

Background There is an increasing demand for mental health services for young people, which may vary across the year. Objective To determine whether there are seasonal patterns in primary care antidepressant prescribing and mental health issues in... Read More about Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data.

Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study (2023)
Journal Article

Objective: To compare use of healthcare services and reasons for attendance by children and young people (CYP) with attention-deficit/hyperactivity disorder (ADHD) versus non-ADHD controls. Design: Population-based matched case-control study. Setting... Read More about Use of healthcare services before diagnosis of attention-deficit/hyperactivity disorder: a population-based matched case-control study.

A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis. (2023)
Journal Article

Alzheimer’s Disease (AD) is a neurodegenerative disease that commonly occurs in older people. It is characterized by both cognitive and functional impairment. However, as AD has an unclear pathological cause, it can be hard to diagnose with confidenc... Read More about A comparative study of GNN and MLP based machine learning for the diagnosis of Alzheimer's Disease involving data synthesis..

Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis (2023)
Journal Article

Background: The youngest children in a school class are more likely than the oldest to be diagnosed with ADHD, but this relative age effect is less frequent in older than in younger school-grade children. However, no study has explored the associatio... Read More about Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis.

Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial (2023)
Journal Article

Background: Mental health problems affect 1 in 6 workers annually and are one of the leading causes of sickness absence, with stress, anxiety, and depression being responsible for half of all working days lost in the United Kingdom. Primary intervent... Read More about Digital Training Program for Line Managers (Managing Minds at Work): Protocol for A Feasibility Pilot Cluster Randomised Controlled Trial.

Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research (2023)
Journal Article

Tinnitus (the perception of sound in the absence of any corresponding external source) is highly prevalent and can be distressing. There are unanswered questions about how tinnitus, suicidal thoughts, and suicidal behaviours co-occur and interact. To... Read More about Tinnitus, Suicide, and Suicidal Ideation: A Scoping Review of Primary Research.

Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage (2023)
Journal Article

Background Outcome after acute spontaneous (non‐traumatic) intracerebral haemorrhage (ICH) is influenced by haematoma volume. ICH expansion occurs in about 20% of people with acute ICH. Early haemostatic therapy might improve outcome by limiting ICH... Read More about Haemostatic therapies for stroke due to acute, spontaneous intracerebral haemorrhage.

Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months (2023)
Journal Article

Background: Despite the known health costs of persistent depression, there is no established service framework for the treatment of this disorder and a lack of long-term outcome data to inform commissioning. To address this gap, we report the long-te... Read More about Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task (2023)
Journal Article

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in- Noise Task.

Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task (2023)
Journal Article

Listening effort and fatigue are common experiences when conversing in noisy environments. Much research has investigated listening effort in relation to listening demand using the speech-in-noise paradigm. Recent conceptualizations of listening effo... Read More about Previous Mental Load and Incentives Influence Anticipatory Arousal as Indexed by the Baseline Pupil Diameter in a Speech-in-Noise Task.

Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist (2023)
Presentation / Conference

Situation: eHealth interventions are a possible solution for rising dementia care costs and potential negative effects on carers Problem: Few evidence-based eHealth interventions are implemented in practice Solution : Adapt existing implementa... Read More about Optimizing implementation of eHealth for dementia: Lessons from developing an eHealth Implementation Readiness (EmpRess) checklist.

The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills (2023)
Journal Article

The current study investigated the effects of metacognitive and executive function (EF) training on childhood EF (inhibition, working memory [WM], cognitive flexibility, and proactive/reactive control) and academic skills (reading, reasoning, and mat... Read More about The effect of metacognitive executive function training on children's executive function, proactive control, and academic skills.

Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review (2023)
Journal Article

Background: Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, br... Read More about Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review.

Understanding and exploring the cost of poor mental health at work for organisations and society (2023)
Book Chapter

This chapter explores the cost of mental health at work from an employer and societal perspective. We aim to present and reflect on the available evidence of the economic burden and human cost posed by poor mental health at work. A fuller understandi... Read More about Understanding and exploring the cost of poor mental health at work for organisations and society.

Social anxiety is more likely to influence reputation management decisions than autistic traits (2023)
Journal Article

People manage their social reputation by selectively sharing achievements, thereby shaping the way others think about them. Autistic traits and social anxiety may have opposing impacts on reputation management. This study aimed to identify the influe... Read More about Social anxiety is more likely to influence reputation management decisions than autistic traits.

CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism (2023)
Journal Article

Purpose: Albinism is a congenital disorder affecting pigmentation levels, structure, and function of the visual system. The identification of anatomical changes typical for people with albinism (PWA), such as optic chiasm malformations, could become... Read More about CHIASM-Net: Artificial Intelligence-Based Direct Identification of Chiasmal Abnormalities in Albinism.

Management standards and burnout among surgeons in the United Kingdom (2023)
Journal Article

Background Burnout arising from chronic work-related stress is endemic among surgeons in the UK. Identification of contributory and modifiable psychosocial work characteristics could inform risk reduction activities. Aims We aimed to assess th... Read More about Management standards and burnout among surgeons in the United Kingdom.

Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis (2023)
Journal Article

Background Several computerised cognitive tests (e.g. continuous performance test) have been developed to support the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). Here, we appraised the evidence-base underpinning the use o... Read More about Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis.

Transient elastography and video recovery narrative access to support recovery from alcohol misuse: development of a novel intervention for use in community alcohol treatment services (2023)
Journal Article

Background: Mortality from alcohol-related liver disease has risen significantly for three decades. Transient elastography (TE) is a non-invasive test providing a numerical marker of liver disease. Preliminary evidence suggests that receiving TE can... Read More about Transient elastography and video recovery narrative access to support recovery from alcohol misuse: development of a novel intervention for use in community alcohol treatment services.