All Outputs (290)

Fitting a Hearing Aid on the Better Ear, Worse Ear, or Both: Associations of Hearing-aid Fitting Laterality with Outcomes in a Large Sample of US Veterans (2023)
Journal Article

Longitudinal electronic health records from a large sample of new hearing-aid (HA) recipients in the US Veterans Affairs healthcare system were used to evaluate associations of fitting laterality with long-term HA use persistence as measured by batte... Read More about Fitting a Hearing Aid on the Better Ear, Worse Ear, or Both: Associations of Hearing-aid Fitting Laterality with Outcomes in a Large Sample of US Veterans.

New horizons in hearing conditions (2023)
Journal Article

Hearing conditions such as hearing loss, tinnitus and hyperacusis are highly prevalent in the population and can severely impact communication and quality of life. Hearing is affected by multiple factors, including heredity, noise exposure, age, sex,... Read More about New horizons in hearing conditions.

Mental wellbeing and psychosocial working conditions of autistic veterinary surgeons in the UK (2023)
Journal Article

Background: Certain autistic characteristics (such as hyper-focus and attention to detail) are valued by veterinary surgeons and autistic adults may disproportionately self-select into the profession. Links between mental wellbeing and retention in t... Read More about Mental wellbeing and psychosocial working conditions of autistic veterinary surgeons in the UK.

The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED) (2023)
Journal Article

Background. The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise and functional activity programme to participants living with dementia. A Randomised Controlled Trial (RCT) showed no measurable be... Read More about The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED).

Spatial organisation of the mesoscale connectome: A feature influencing synchrony and metastability of network dynamics (2023)
Journal Article

Significant research has investigated synchronisation in brain networks, but the bulk of this work has explored the contribution of brain networks at the macroscale. Here we explore the effects of changing network topology on functional dynamics in s... Read More about Spatial organisation of the mesoscale connectome: A feature influencing synchrony and metastability of network dynamics.

The ‘barcode sign’ seen on optical coherence tomography of extensive corneal vascularization (2023)
Journal Article

Optical Coherence Tomography (OCT) is used extensively in imaging the cornea in health and disease. OCT delineates interfaces of differing refractive indices, which often but not always correspond to histological features of the tissue. Interpretatio... Read More about The ‘barcode sign’ seen on optical coherence tomography of extensive corneal vascularization.

Blood pressure medication and acute kidney injury after intracerebral haemorrhage: an analysis of the ATACH-II trial (2023)
Journal Article

Background: Acute blood pressure (BP) reduction is standard of care after acute intracerebral haemorrhage (ICH). More acute BP reduction is associated with acute kidney injury (AKI). It is not known if the choice of antihypertensive medications affec... Read More about Blood pressure medication and acute kidney injury after intracerebral haemorrhage: an analysis of the ATACH-II trial.

Editorial: Hearing loss rehabilitation and higher-order auditory and cognitive processing (2023)
Journal Article

Characterisation of the treatment provided for children with unilateral hearing loss (2023)
Journal Article

Background: Children with permanent unilateral hearing loss (UHL) are an understudied population, with limited data to inform the guidelines on clinical management. There is a funding gap in healthcare provision for the children with UHL in the Unite... Read More about Characterisation of the treatment provided for children with unilateral hearing loss.

Early MRI Predictors of Relapse in Primary Central Nervous System Lymphoma Treated with MATRix Immunochemotherapy (2023)
Journal Article

Primary Central Nervous System Lymphoma (PCNSL) is a highly malignant brain tumour. We investigated dynamic changes in tumour volume and apparent diffusion coefficient (ADC) measurements for predicting outcome following treatment with MATRix chemothe... Read More about Early MRI Predictors of Relapse in Primary Central Nervous System Lymphoma Treated with MATRix Immunochemotherapy.

Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey (2023)
Journal Article

Background Tics are common in children and young people and may persist into adulthood. Tics can cause challenges with social, occupational, physical, and academic functioning. The current study explores the perceptions of adults with tics and paren... Read More about Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey.

Usability and feasibility of PreventS-MD webapp for stroke prevention (2023)
Journal Article

Background: Most strokes and cardiovascular diseases (CVDs) are potentially preventable if their risk factors are identified and well controlled. Digital platforms, such as the PreventS-MD webapp (PreventS-MD) may aid health care professionals (HCPs)... Read More about Usability and feasibility of PreventS-MD webapp for stroke prevention.

Bleeding with intensive versus guideline antiplatelet therapy in acute cerebral ischaemia (2023)
Journal Article

Intensive antiplatelet therapy did not reduce recurrent stroke/transient ischaemic attack (TIA) events as compared with guideline treatment in the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial, but did increase th... Read More about Bleeding with intensive versus guideline antiplatelet therapy in acute cerebral ischaemia.

Remote ischemic conditioning for stroke: A critical systematic review (2023)
Journal Article

Remote ischemic conditioning (RIC) is the application of brief periods of ischemia to an organ or tissue with the aim of inducing protection from ischemia in a distant organ. It was first developed as a cardioprotective strategy but has been increasi... Read More about Remote ischemic conditioning for stroke: A critical systematic review.

The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know? (2023)
Journal Article

The assessment of Attention-Deficit/Hyperactivity Disorder (ADHD) typically relies on subjective observer reports from parents, teachers, or the young person, combined with clinical observation and history. Children and young people often experience... Read More about The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know?.

Using mobile health technology to assess childhood autism in low-resource community settings in India: An innovation to address the detection gap (2023)
Journal Article

A diagnosis of autism typically depends on clinical assessments by highly trained professionals. This high resource demand poses a challenge in low-resource settings. Digital assessment of neurodevelopmental symptoms by non-specialists provides a pot... Read More about Using mobile health technology to assess childhood autism in low-resource community settings in India: An innovation to address the detection gap.

Relationship between autonomic arousal and attention orienting in children and adolescents with ADHD, autism and co-occurring ADHD and autism (2023)
Journal Article

Introduction Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) may be characterized by different profiles of visual attention orienting. However, there are also many inconsistent findings emerging from the literature... Read More about Relationship between autonomic arousal and attention orienting in children and adolescents with ADHD, autism and co-occurring ADHD and autism.

Listening efficiency in adult cochlear-implant users compared with normally-hearing controls at ecologically relevant signal-to-noise ratios (2023)
Journal Article

Introduction: Due to having to work with an impoverished auditory signal, cochlear-implant (CI) users may experience reduced speech intelligibility and/or increased listening effort in real-world listening situations, compared to their normally-heari... Read More about Listening efficiency in adult cochlear-implant users compared with normally-hearing controls at ecologically relevant signal-to-noise ratios.

TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor (2023)
Journal Article

Ischaemic stroke, accompanied by neuroinflammation, impairs blood–brain barrier (BBB) integrity through a complex mechanism involving activation of both RhoA/Rho kinase/myosin light chain-2 and neurokinin 1 receptor (NK1R). Using an in vitro model of... Read More about TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor.

Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination (2023)
Journal Article

Background: People with multiple sclerosis (pwMS) treated with certain disease-modifying therapies (DMTs) have attenuated IgG response following COVID-19 vaccination; however, the clinical consequences remain unclear. Objective: To report CO... Read More about Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination.