All Outputs (135)

Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI (2013)
Journal Article
Lilburn, D. M., Hughes-Riley, T., Six, J. S., Stupic, K. F., Shaw, D. E., Pavlovskaya, G. E., & Meersmann, T. (2013). Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI. PLoS ONE, 8(8), Article e73468. https://doi.org/10.1371/journal.pone.0073468

Ex vivo rodent lung models are explored for physiological measurements of respiratory function with hyperpolarized (hp) 129Xe MRI. It is shown that excised lung models allow for simplification of the technical challenges involved and provide valuable... Read More about Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI.

Neural primacy of the salience processing system in schizophrenia (2013)
Journal Article
Palaniyappan, L., Simmonite, M., White, T., Liddle, E., & Liddle, P. (2013). Neural primacy of the salience processing system in schizophrenia. Neuron, 79(4), https://doi.org/10.1016/j.neuron.2013.06.027

For effective information processing, two large-scale distributed neural networks appear to be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex (DLPFC) and a salience system anchored on the anterior insula. Aberr... Read More about Neural primacy of the salience processing system in schizophrenia.

A survey of tobacco dependence treatment guidelines in 121 countries (2013)
Journal Article
Piné-Abata, H., McNeill, A., Raw, M., Bitton, A., Rigotti, N., & Murray, R. (2013). A survey of tobacco dependence treatment guidelines in 121 countries. Addiction, 108(8), https://doi.org/10.1111/add.12158

Aims To report progress among Parties to the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in developing national tobacco treatment guidelines in accordance with FCTC Article 14 guideline recommendations. Design... Read More about A survey of tobacco dependence treatment guidelines in 121 countries.

Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics (2013)
Journal Article
Tench, C. R., Tanasescu, R., Auer, D. P., & Constantinescu, C. S. (2013). Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics. PLoS ONE, 8(7), Article e70143. https://doi.org/10.1371/journal.pone.0070143

Coordinate based meta-analysis (CBMA) is widely used to find regions of consistent activation across fMRI studies that have been selected for their functional relevance to a given hypothesis. Only reported coordinates (foci), and a model of their spa... Read More about Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics.

HTR4 gene structure and altered expression in the developing lung (2013)
Journal Article
Hodge, E., Nelson, C. P., Miller, S., Billington, C. K., Stewart, C. E., Swan, C., …Sayers, I. (2013). HTR4 gene structure and altered expression in the developing lung. Respiratory Research, 14(77), https://doi.org/10.1186/1465-9921-14-77

Background: Meta-analyses of genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) spanning the 5-hydroxytryptamine receptor 4 (5-HT4R) gene (HTR4) associated with lung function. The aims of this study were t... Read More about HTR4 gene structure and altered expression in the developing lung.

Rational prescribing is important in all settings (2013)
Journal Article
Choonara, I. (2013). Rational prescribing is important in all settings. Archives of Disease in Childhood, 98(9), https://doi.org/10.1136/archdischild-2013-304559

‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services (2013)
Journal Article
Hall, C. L., Newell, K., Taylor, J., Sayal, K., Swift, K. D., & Hollis, C. (2013). ‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services. BMC Psychiatry, 13(186), https://doi.org/10.1186/1471-244X-13-186

Background: Once considered to be a disorder restricted to childhood, Attention Deficit/Hyperactivity Disorder (ADHD) is now recognised to persist into adult life. However, service provision for adults with ADHD is limited. Additionally, there is lit... Read More about ‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services.

The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study (2013)
Journal Article
Yates, J., & James, D. (2013). The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study. BMC Medical Education, 13, Article 32. https://doi.org/10.1186/1472-6920-13-32

Background The UK Clinical Aptitude Test (UKCAT) was introduced in 2006 as an additional tool for the selection of medical students. It tests mental ability in four distinct domains (Verbal Reasoning, Quantitative Reasoning, Abstract Reasoning, and... Read More about The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study.

The remediation challenge: theoretical and methodological insights from a systematic review: The challenge of remediation (2013)
Journal Article
Cleland, J., Leggett, H., Sandars, J., Costa, M. J., Patel, R., & Moffat, M. (2013). The remediation challenge: theoretical and methodological insights from a systematic review: The challenge of remediation. Medical Education, 47(3), 242-251. https://doi.org/10.1111/medu.12052

Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129 (2012)
Journal Article
Six, J. S., Hughes-Riley, T., Stupic, K. F., Pavlovskaya, G. E., & Meersmann, T. (2012). Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129. PLoS ONE, 7(11), Article e49927. https://doi.org/10.1371/journal.pone.0049927

yperpolarized (hp) 129Xe and hp 83Kr for magnetic resonance imaging (MRI) are typically obtained through spin-exchange optical pumping (SEOP) in gas mixtures with dilute concentrations of the respective noble gas. The usage of dilute noble gases mix... Read More about Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129.

Bacterial involvement in otitis media with effusion (2012)
Journal Article
Daniel, M., Imtiaz-Umer, S., Fergie, N., Birchall, J., & Bayston, R. (2012). Bacterial involvement in otitis media with effusion. International Journal of Pediatric Otorhinolaryngology, 76(10), https://doi.org/10.1016/j.ijporl.2012.06.013

Objective Otitis media with effusion (OME), a common chronic childhood condition affecting hearing, is thought to be a result of bacterial infection, with biofilms recently implicated. Although bacterial DNA can be detected by polymerase chain react... Read More about Bacterial involvement in otitis media with effusion.

Focus on underperformance, and how to address this (2012)
Journal Article
Cleland, J., & Patel, R. (2012). Focus on underperformance, and how to address this. Clinical Teacher, 9(1), 65-66. https://doi.org/10.1111/j.1743-498x.2011.00522.x

Should applicants to Nottingham University Medical School study a non-science A-level?: a cohort study (2009)
Journal Article
Yates, J., Smith, J., James, D., & Ferguson, E. (2009). Should applicants to Nottingham University Medical School study a non-science A-level?: a cohort study. BMC Medical Education, 9, Article 5. https://doi.org/10.1186/1472-6920-9-5

Background It has been suggested that studying non-science subjects at A-level should be compulsory for medical students. Our admissions criteria specify only Biology, Chemistry and one or more additional subjects. This study aimed to determine whet... Read More about Should applicants to Nottingham University Medical School study a non-science A-level?: a cohort study.

Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides (2008)
Journal Article
Tarhoni, M. H., Lister, T., Ray, D. E., & Carter, W. G. (2008). Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides. Biomarkers, 13(4), https://doi.org/10.1080/13547500801973563

We have evaluated the potential of plasma albumin to provide a sensitive biomarker of exposure to commonly used organophosphorus pesticides in order to complement the widely used measure of acetylcholinesterase (AChE) inhibition. Rat or human plasma... Read More about Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides.

The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia (2002)
Journal Article
Seedhouse, C., Bainton, R., Lewis, M., Harding, A., Russell, N., & Das-Gupta, E. (2002). The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia. Blood, 100(10), 3761-3766. https://doi.org/10.1182/blood-2002-04-1152

Polymorphisms in several DNA repair genes have been described. These polymorphisms may affect DNA repair capacity and modulate cancer susceptibility by means of gene-environment interactions. We investigated DNA repair capacity and its association wi... Read More about The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia.