All Outputs (132)

Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics (2013)
Journal Article

Coordinate based meta-analysis (CBMA) is widely used to find regions of consistent activation across fMRI studies that have been selected for their functional relevance to a given hypothesis. Only reported coordinates (foci), and a model of their spa... Read More about Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics.

HTR4 gene structure and altered expression in the developing lung (2013)
Journal Article

Background: Meta-analyses of genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) spanning the 5-hydroxytryptamine receptor 4 (5-HT4R) gene (HTR4) associated with lung function. The aims of this study were t... Read More about HTR4 gene structure and altered expression in the developing lung.

Rational prescribing is important in all settings (2013)
Journal Article

‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services (2013)
Journal Article

Background: Once considered to be a disorder restricted to childhood, Attention Deficit/Hyperactivity Disorder (ADHD) is now recognised to persist into adult life. However, service provision for adults with ADHD is limited. Additionally, there is lit... Read More about ‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services.

The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study (2013)
Journal Article

Background The UK Clinical Aptitude Test (UKCAT) was introduced in 2006 as an additional tool for the selection of medical students. It tests mental ability in four distinct domains (Verbal Reasoning, Quantitative Reasoning, Abstract Reasoning, and... Read More about The UK clinical aptitude test and clinical course performance at Nottingham: a prospective cohort study.

The remediation challenge: theoretical and methodological insights from a systematic review: The challenge of remediation (2013)
Journal Article

Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129 (2012)
Journal Article

yperpolarized (hp) 129Xe and hp 83Kr for magnetic resonance imaging (MRI) are typically obtained through spin-exchange optical pumping (SEOP) in gas mixtures with dilute concentrations of the respective noble gas. The usage of dilute noble gases mix... Read More about Pathway to cryogen free production of hyperpolarized krypton-83 and xenon-129.

Bacterial involvement in otitis media with effusion (2012)
Journal Article

Objective Otitis media with effusion (OME), a common chronic childhood condition affecting hearing, is thought to be a result of bacterial infection, with biofilms recently implicated. Although bacterial DNA can be detected by polymerase chain react... Read More about Bacterial involvement in otitis media with effusion.

Focus on underperformance, and how to address this (2012)
Journal Article

Should applicants to Nottingham University Medical School study a non-science A-level?: a cohort study (2009)
Journal Article

Background It has been suggested that studying non-science subjects at A-level should be compulsory for medical students. Our admissions criteria specify only Biology, Chemistry and one or more additional subjects. This study aimed to determine whet... Read More about Should applicants to Nottingham University Medical School study a non-science A-level?: a cohort study.

Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides (2008)
Journal Article

We have evaluated the potential of plasma albumin to provide a sensitive biomarker of exposure to commonly used organophosphorus pesticides in order to complement the widely used measure of acetylcholinesterase (AChE) inhibition. Rat or human plasma... Read More about Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides.

The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia (2002)
Journal Article

Polymorphisms in several DNA repair genes have been described. These polymorphisms may affect DNA repair capacity and modulate cancer susceptibility by means of gene-environment interactions. We investigated DNA repair capacity and its association wi... Read More about The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia.