A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms

Zareian, Nahid; Eremin, Oleg; Pandha, Hardev; Baird, Richard; Kwatra, Vineet; Funingana, Gabriel; Verma, Chandan; Choy, Desmond; Hargreaves, Steven; Moghimi, Pejvak; Shepherd, Adrian; Lobo, Dileep N; Eremin, Jennifer; Farzaneh, Farzin; Kordasti, Shahram; Spicer, James

doi:10.3389/ebm.2024.10021

All Outputs (2)

Smoking is a risk factor for autoimmune hepatitis: An English registry-based case-control study (2024)
Journal Article

Purpose: Smoking is a risk factor for some autoimmune diseases, but its association with autoimmune hepatitis remains unknown. We conducted a population-based matched case–control study to examine the association between tobacco smoking and the risk... Read More about Smoking is a risk factor for autoimmune hepatitis: An English registry-based case-control study.

A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms (2024)
Journal Article

The presence of inhibitory immune cells and difficulty in generating activated effector T cells remain obstacles to development of effective cancer vaccines. We designed a vaccine regimen combining human telomerase reverse transcriptase (hTERT) pepti... Read More about A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms.