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Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England (2014)
Journal Article
Kuo, C., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2014). Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England. Journal of the American Medical Association, 312(24), https://doi.org/10.1001/jama.2014.14484

Gout is caused by urate crystal deposition secondary to persistent hyperuricemia. Current guidelines recommend urate-lowering treatment to prevent crystal deposition and encourage crystal dissolution for patients with more severe gout or concomitant... Read More about Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England.

The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012 (2014)
Journal Article
Rees, F., Doherty, M., Grainge, M. J., Davenport, G., Lanyon, P., & Zhang, W. (in press). The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012. Annals of the Rheumatic Diseases, 75(1), https://doi.org/10.1136/annrheumdis-2014-206334

Objectives: To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999–2012. Methods: A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculate... Read More about The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012.

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study (2014)
Journal Article
Doherty, S., Zhang, W., Maciewicz, R., Doherty, M., Muir, K., Abhishek, A., & Valdes, A. M. (2014). The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study. Arthritis Research and Therapy, 16(1), Article R25. https://doi.org/10.1186/ar4453

Introduction Chondrocalcinosis (CC) most commonly results from calcium pyrophosphate crystal deposition (CPPD). The objective of this study is to examine the association between candidate single-nucleotide polymorphisms (SNPs) and radiographic CC.... Read More about The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study.

Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study (2014)
Journal Article
Kuo, C. F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2015). Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study. Annals of the Rheumatic Diseases, 74(4), 661-667. https://doi.org/10.1136/annrheumdis-2013-204463

Objectives: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. Methods: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study.