All Outputs (60)

Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood (2015)
Journal Article

The risk factors for childhood overweight and obesity are known and can be identified antenatally or during infancy, however, the majority of effective interventions are designed for older children. This review identified interventions designed to re... Read More about Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood.

Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study (2015)
Journal Article

BACKGROUND & AIMS: Cirrhosis because of alcohol could be avoided if drinking behaviour could be altered earlier in the disease course. Our aim was to quantify the burden of morbidities in patients prior to alcoholic cirrhosis diagnosis, as this may... Read More about Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study.

Pharmacological interventions for promoting smoking cessation during pregnancy (2015)
Journal Article

Background Smoking in pregnancy is a public health problem. When used by non-pregnant smokers, pharmacotherapies (nicotine replacement therapy (NRT), bupropion and varenicline) are effective for smoking cessation, however, their efficacy and safet... Read More about Pharmacological interventions for promoting smoking cessation during pregnancy.

Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database (2015)
Journal Article

Background: Epilepsy is a serious condition which can profoundly affect an individual’s life. While there is some evidence to suggest an association between antidepressant use and epilepsy and seizures it is conflicting and not conclusive. Antidepres... Read More about Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database.

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial (2015)
Journal Article

Importance: Case reports and series suggest hematopoietic stem cell transplantation (HSCT) may benefit some patients with Crohn disease. Objective: To evaluate the effect of autologous HSCT on refractory Crohn disease. Design, Setting, and Pa... Read More about Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.

Cycling infrastructure for reducing cycling injuries in cyclists (2015)
Journal Article

Background: Cycling is an attractive form of transport. It is beneficial to the individual as a form of physical activity that may fit more readily into an individual’s daily routine, such as for cycling to work and to the shops, than other physical... Read More about Cycling infrastructure for reducing cycling injuries in cyclists.

Risk and protective factors for falls on stairs in young children: multicentre case–control study (2015)
Journal Article

Aim: To investigate risk and protective factors for stair falls in children aged

Small area synthetic estimates of smoking prevalence during pregnancy in England (2015)
Journal Article

Background: Complete and accurate data on maternal smoking prevalence during pregnancy are not available at a local geographical scale in England. We employ a synthetic estimation approach to predict the expected prevalence of smoking during pregnanc... Read More about Small area synthetic estimates of smoking prevalence during pregnancy in England.

Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care (2015)
Journal Article

Background: In the UK, studies suggest that the transition from hospital to home after an injury can be a difficult time and many patients report feeling inadequately prepared. Patients often use primary care services after hospital discharge. These... Read More about Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care.

Risk and protective factors for falls on one level in young children: multicentre case-control study (2015)
Journal Article

Background: Childhood falls are an important global public health problem, but there is a lack of evidence about their prevention. Falls on one level result in considerable morbidity and they are costly to health services. Objective: To estimate o... Read More about Risk and protective factors for falls on one level in young children: multicentre case-control study.

The association of mood disorders with breast cancer survival: An investigation of linked cancer registration and hospital admission data for South East England (2015)
Journal Article

Background: Data linkage studies find that depression before or after a breast cancer diagnosis predicts reduced survival. This study aimed to determine whether depression or bipolar recorded in routine hospital admission data independently predicts... Read More about The association of mood disorders with breast cancer survival: An investigation of linked cancer registration and hospital admission data for South East England.

Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009 (2015)
Journal Article

Copyright © 2015 Published by Elsevier Ltd. All rights reserved. Objective We assessed the association between population resection rates, hospital procedure volume and death rates in pancreatic cancer patients in England. Design Patients diagnosed w... Read More about Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009.

Using qualitative interviews with nihr crn research midwives to refine trial recruitment methods (2015)
Journal Article

Systematic critical review of previous economic evaluations of smoking cessation during pregnancy (2015)
Journal Article

Objective: To identify and critically assess previous economic evaluations of smoking cessation interventions delivered during pregnancy. Design: Qualitative review of studies with primary data collection or hypothetical modelling. Quality assesse... Read More about Systematic critical review of previous economic evaluations of smoking cessation during pregnancy.

Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study (2015)
Journal Article

Study question: Is it possible to develop and externally validate risk prediction equations to estimate the 10 year risk of blindness and lower limb amputation in patients with diabetes aged 25-84 years? Methods: This was a prospective cohort stud... Read More about Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study.

Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink (2015)
Journal Article

Study question: What is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices? Methods: A cross sectional study included all adult patients pot... Read More about Examining variations in prescribing safety in UK general practice: cross sectional study using the Clinical Practice Research Datalink.

Promoting physical activity in older people in general practice: ProAct65+ cluster randomised controlled trial (2015)
Journal Article

The London Exercise And Pregnant smokers (LEAP) trial: a randomised controlled trial of physical activity for smoking cessation in pregnancy with an economic evaluation (2015)
Journal Article

BACKGROUND: Smoking during pregnancy is the main preventable cause of poor birth outcomes. Improved methods are needed to help women to stop smoking during pregnancy. Pregnancy provides a compelling rationale for physical activity (PA) interventions... Read More about The London Exercise And Pregnant smokers (LEAP) trial: a randomised controlled trial of physical activity for smoking cessation in pregnancy with an economic evaluation.

The adaptation and uptake evaluation of an SMS text message smoking cessation programme (MiQuit) for use in antenatal care (2015)
Journal Article

Objectives: To adapt a tailored SMS text message smoking cessation intervention (MiQuit) for use without active health professional endorsement in routine antenatal care settings, to estimate ‘real world’ uptake and test the feasibility of its use. D... Read More about The adaptation and uptake evaluation of an SMS text message smoking cessation programme (MiQuit) for use in antenatal care.

Accuracy of methods for detecting an irregular pulse and suspected atrial fibrillation: a systematic review and meta-analysis (2015)
Journal Article

Background: Pulse palpation has been recommended as the first step of screening to detect atrial fibrillation. We aimed to determine and compare the accuracy of different methods for detecting pulse irregularities caused by atrial fibrillation. Me... Read More about Accuracy of methods for detecting an irregular pulse and suspected atrial fibrillation: a systematic review and meta-analysis.