Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009

Coupland, V. H.; Konfortion, J.; Jack, R. H.; Allum, W.; Kocher, H. M.; Riaz, S. P.; L�chtenborg, M.; M�ller, H.

Abstract

Copyright © 2015 Published by Elsevier Ltd. All rights reserved. Objective We assessed the association between population resection rates, hospital procedure volume and death rates in pancreatic cancer patients in England. Design Patients diagnosed with pancreatic cancer were identified from a linked cancer registration and Hospital Episode Statistics dataset. Cox regression analyses were used to assess all-cause mortality according to resection quintile and hospital volume, adjusting for sex, age, deprivation and comorbidity. Results There were 31,973 pancreatic cancer patients studied, 2580 had surgery. Increasing resection rates were associated with lower mortality among all patients (χ2(1df) = 176.18, ptrend < 0.001), with an unadjusted hazard ratio (HR) of 0.78 95%CI [0.75 to 0.81] in the highest versus the lowest resection quintile. Adjustment changed the estimate slightly (HR 0.82, 95%CI [0.79 to 0.85], (χ2(1df) = 99.44, ptrend < 0.001)). Among patients that underwent surgery, higher procedure volume was associated with lower mortality (HR = 0.88 95%CI [0.75-1.03] in hospitals carrying out 30+ versus

Citation

Coupland, V. H., Konfortion, J., Jack, R. H., Allum, W., Kocher, H. M., Riaz, S. P., Lüchtenborg, M., & Møller, H. (2016). Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009. EJSO - European Journal of Surgical Oncology, 42(2), 190-196. https://doi.org/10.1016/j.ejso.2015.11.003

• Journal Article Type: Article
• Acceptance Date: Nov 8, 2015
• Online Publication Date: Nov 17, 2015
• Publication Date: Feb 1, 2016
• Deposit Date: Apr 26, 2021
• Journal: European Journal of Surgical Oncology
• Print ISSN: 0748-7983
• Electronic ISSN: 1532-2157
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 42
• Issue: 2
• Pages: 190-196
• DOI: https://doi.org/10.1016/j.ejso.2015.11.003
• Public URL: https://nottingham-repository.worktribe.com/output/3223679
• Publisher URL: https://www.ejso.com/article/S0748-7983(15)00842-2/fulltext