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Comparing the cost-effectiveness and clinical effectiveness of a new community in-reach rehabilitation service with the cost-effectiveness and clinical effectiveness of an established hospital-based rehabilitation service for older people: a pragmatic randomised controlled trial with microcost and qualitative analysis – the Community In-reach Rehabilitation And Care Transition (CIRACT) study (2016)
Journal Article
Sahota, O., Pulikottil-Jacob, R., Marshall, F., Montgomery, A., Tan, W., Sach, T., …Waring, J. (2016). Comparing the cost-effectiveness and clinical effectiveness of a new community in-reach rehabilitation service with the cost-effectiveness and clinical effectiveness of an established hospital-based rehabilitation service for older people: a pragmatic randomised controlled trial with microcost and qualitative analysis – the Community In-reach Rehabilitation And Care Transition (CIRACT) study. Health Services and Delivery Research, 4(7), https://doi.org/10.3310/hsdr04070

Background: Older people represent a significant proportion of patients admitted to hospital as a medical emergency. Compared with the care of younger patients, their care is more challenging, their stay in hospital is much longer, their risk of ho... Read More about Comparing the cost-effectiveness and clinical effectiveness of a new community in-reach rehabilitation service with the cost-effectiveness and clinical effectiveness of an established hospital-based rehabilitation service for older people: a pragmatic randomised controlled trial with microcost and qualitative analysis – the Community In-reach Rehabilitation And Care Transition (CIRACT) study.

The NHS Health Check in England: an evaluation of the first 4?years (2016)
Journal Article
Robson, J., Dostal, I., Sheikh, A., Eldridge, S., Madurasinghe, V., Griffiths, C., …Hippisley-Cox, J. (2016). The NHS Health Check in England: an evaluation of the first 4 years. BMJ Open, 6(1), Article e008840. https://doi.org/10.1136/bmjopen-2015-008840

Objectives: To describe implementation of a new national preventive programme to reduce cardiovascular morbidity. Design: Observational study over 4 years (April 2009—March 2013). Setting: 655 general practices across England from the QResear... Read More about The NHS Health Check in England: an evaluation of the first 4?years.

Frailty predicts trajectories of quality of life over time among British community-dwelling older people (2016)
Journal Article
Kojima, G., Iliffe, S., Morris, R., Taniguchi, Y., Kendrick, D., Skelton, D. A., …Bowling, A. (in press). Frailty predicts trajectories of quality of life over time among British community-dwelling older people. Quality of Life Research, https://doi.org/10.1007/s11136-015-1213-2

Purpose: To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. Methods: Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailt... Read More about Frailty predicts trajectories of quality of life over time among British community-dwelling older people.

Pregnant women’s experiences and views on an “opt-out” referral pathway to specialist smoking cessation support: a qualitative evaluation (2016)
Journal Article
Sloan, M., Campbell, K., Bowker, K., Coleman, T., Cooper, S., Brafman-Price, B., & Naughton, F. (in press). Pregnant women’s experiences and views on an “opt-out” referral pathway to specialist smoking cessation support: a qualitative evaluation. Nicotine and Tobacco Research, 18(5), https://doi.org/10.1093/ntr/ntv273

Introduction: Smoking in pregnancy remains an important and costly public health concern with policy makers worldwide researching methods to aid cessation. UK government guidelines recommend implementation of an “opt-out” (ie, whether requested or no... Read More about Pregnant women’s experiences and views on an “opt-out” referral pathway to specialist smoking cessation support: a qualitative evaluation.

Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood (2015)
Journal Article
Redsell, S. A., Edmonds, B., Swift, J. A., Siriwardena, A. N., Weng, S., Nathan, D., & Glazebrook, C. (2016). Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood. Maternal and Child Nutrition, 12(1), https://doi.org/10.1111/mcn.12184

The risk factors for childhood overweight and obesity are known and can be identified antenatally or during infancy, however, the majority of effective interventions are designed for older children. This review identified interventions designed to re... Read More about Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood.

Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study (2015)
Journal Article
Otete, H. E., Orton, E., Fleming, K. M., & West, J. (2016). Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study. Liver International, 36(4), 538-546. https://doi.org/10.1111/liv.13002

BACKGROUND & AIMS: Cirrhosis because of alcohol could be avoided if drinking behaviour could be altered earlier in the disease course. Our aim was to quantify the burden of morbidities in patients prior to alcoholic cirrhosis diagnosis, as this may... Read More about Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study.

Pharmacological interventions for promoting smoking cessation during pregnancy (2015)
Journal Article
Coleman, T., Chamberlain, C., Davey, M., Cooper, S., & Leonardi-Bee, J. (2015). Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD010078.pub2

Background Smoking in pregnancy is a public health problem. When used by non-pregnant smokers, pharmacotherapies (nicotine replacement therapy (NRT), bupropion and varenicline) are effective for smoking cessation, however, their efficacy and safet... Read More about Pharmacological interventions for promoting smoking cessation during pregnancy.

Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database (2015)
Journal Article
Hill, T., Coupland, C., Morriss, R. K., Arthur, A., Moore, M., & Hippisley-Cox, J. (2015). Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database. BMC Psychiatry, 15, Article 315. https://doi.org/10.1186/s12888-015-0701-9

Background: Epilepsy is a serious condition which can profoundly affect an individual’s life. While there is some evidence to suggest an association between antidepressant use and epilepsy and seizures it is conflicting and not conclusive. Antidepres... Read More about Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database.

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial (2015)
Journal Article
Hawkey, C. J., Allez, M., Clark, M. M., Labopin, M., Lindsay, J. O., Ricart, E., …Farge, D. (2015). Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial. Journal of the American Medical Association, 314(23), 2524-2534. https://doi.org/10.1001/jama.2015.16700

Importance: Case reports and series suggest hematopoietic stem cell transplantation (HSCT) may benefit some patients with Crohn disease. Objective: To evaluate the effect of autologous HSCT on refractory Crohn disease. Design, Setting, and Pa... Read More about Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.

Cycling infrastructure for reducing cycling injuries in cyclists (2015)
Journal Article
Mulvaney, C. A., Smith, S., Watson, M. C., Parkin, J., Coupland, C., Miller, P., …McClintock, H. (2015). Cycling infrastructure for reducing cycling injuries in cyclists. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD010415.pub2

Background: Cycling is an attractive form of transport. It is beneficial to the individual as a form of physical activity that may fit more readily into an individual’s daily routine, such as for cycling to work and to the shops, than other physical... Read More about Cycling infrastructure for reducing cycling injuries in cyclists.

Risk and protective factors for falls on stairs in young children: multicentre case–control study (2015)
Journal Article
Kendrick, D., Zou, K., Ablewhite, J., Watson, M., Coupland, C., Kay, B., …Reading, R. (2016). Risk and protective factors for falls on stairs in young children: multicentre case–control study. Archives of Disease in Childhood, 101(10), 909-916. https://doi.org/10.1136/archdischild-2015-308486

Aim: To investigate risk and protective factors for stair falls in children aged

Small area synthetic estimates of smoking prevalence during pregnancy in England (2015)
Journal Article
Szatkowski, L., Fahy, S., Coleman, T., Taylor, J., Twigg, L., Moon, G., & Leonardi-Bee, J. (2015). Small area synthetic estimates of smoking prevalence during pregnancy in England. Population Health Metrics, 13(34), https://doi.org/10.1186/s12963-015-0067-8

Background: Complete and accurate data on maternal smoking prevalence during pregnancy are not available at a local geographical scale in England. We employ a synthetic estimation approach to predict the expected prevalence of smoking during pregnanc... Read More about Small area synthetic estimates of smoking prevalence during pregnancy in England.

Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care (2015)
Journal Article
Christie, N., Beckett, K., Earthy, S., Kellezi, B., Sleney, J., Barnes, J., …Kendrick, D. (2016). Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care. British Journal of General Practice, 66(642), e24-e31. https://doi.org/10.3399/bjgp15X688141

Background: In the UK, studies suggest that the transition from hospital to home after an injury can be a difficult time and many patients report feeling inadequately prepared. Patients often use primary care services after hospital discharge. These... Read More about Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care.

Risk and protective factors for falls on one level in young children: multicentre case-control study (2015)
Journal Article
Benford, P., Young, B., Coupland, C., Watson, M., Hindmarch, P., Hayes, M., …Kendrick, D. (2015). Risk and protective factors for falls on one level in young children: multicentre case-control study. Injury Prevention, 21(6), https://doi.org/10.1136/injuryprev-2015-041581

Background: Childhood falls are an important global public health problem, but there is a lack of evidence about their prevention. Falls on one level result in considerable morbidity and they are costly to health services. Objective: To estimate o... Read More about Risk and protective factors for falls on one level in young children: multicentre case-control study.

The association of mood disorders with breast cancer survival: An investigation of linked cancer registration and hospital admission data for South East England (2015)
Journal Article
Kanani, R., Davies, E. A., Hanchett, N., & Jack, R. H. (2016). The association of mood disorders with breast cancer survival: An investigation of linked cancer registration and hospital admission data for South East England. Psycho-Oncology, 25(1), 19-27. https://doi.org/10.1002/pon.4037

Background: Data linkage studies find that depression before or after a breast cancer diagnosis predicts reduced survival. This study aimed to determine whether depression or bipolar recorded in routine hospital admission data independently predicts... Read More about The association of mood disorders with breast cancer survival: An investigation of linked cancer registration and hospital admission data for South East England.

Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009 (2015)
Journal Article
Coupland, V. H., Konfortion, J., Jack, R. H., Allum, W., Kocher, H. M., Riaz, S. P., …Møller, H. (2016). Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009. EJSO - European Journal of Surgical Oncology, 42(2), 190-196. https://doi.org/10.1016/j.ejso.2015.11.003

Copyright © 2015 Published by Elsevier Ltd. All rights reserved. Objective We assessed the association between population resection rates, hospital procedure volume and death rates in pancreatic cancer patients in England. Design Patients diagnosed w... Read More about Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009.

Systematic critical review of previous economic evaluations of smoking cessation during pregnancy (2015)
Journal Article
Jones, M., Lewis, S., Parrott, S., & Coleman, T. (2015). Systematic critical review of previous economic evaluations of smoking cessation during pregnancy. BMJ Open, 5(11), Article e008998. https://doi.org/10.1136/bmjopen-2015-008998

Objective: To identify and critically assess previous economic evaluations of smoking cessation interventions delivered during pregnancy. Design: Qualitative review of studies with primary data collection or hypothetical modelling. Quality assesse... Read More about Systematic critical review of previous economic evaluations of smoking cessation during pregnancy.

Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study (2015)
Journal Article
Hippisley-Cox, J., & Coupland, C. (2015). Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study. BMJ, 351, Article h5441. https://doi.org/10.1136/bmj.h5441

Study question: Is it possible to develop and externally validate risk prediction equations to estimate the 10 year risk of blindness and lower limb amputation in patients with diabetes aged 25-84 years? Methods: This was a prospective cohort stud... Read More about Development and validation of risk prediction equations to estimate future risk of blindness and lower limb amputation in patients with diabetes: cohort study.