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Retroviral integrations contribute to elevated host cancer rates during germline invasion (2021)
Journal Article
McEwen, G. K., Alquezar-Planas, D. E., Dayaram, A., Gillett, A., Tarlinton, R., Mongan, N., …Greenwood, A. D. (2021). Retroviral integrations contribute to elevated host cancer rates during germline invasion. Nature Communications, 12(1), https://doi.org/10.1038/s41467-021-21612-7

© 2021, The Author(s). Repeated retroviral infections of vertebrate germlines have made endogenous retroviruses ubiquitous features of mammalian genomes. However, millions of years of evolution obscure many of the immediate repercussions of retrovira... Read More about Retroviral integrations contribute to elevated host cancer rates during germline invasion.

Promoting Evidence-based Veterinary Medicine through the online resource ‘EBVM Learning’: User feedback (2021)
Journal Article
Sellers, E., Baillie, S., Dean, R., Warman, S., Janicke, H., Arlt, S. P., …Verheyen, K. (2021). Promoting Evidence-based Veterinary Medicine through the online resource ‘EBVM Learning’: User feedback. Veterinary Evidence, 6(1), 1-17. https://doi.org/10.18849/ve.v6i1.392

‘EBVM Learning’ is a freely available resource created in 2015 by an international team with the support of RCVS Knowledge. The resource comprises a series of online modules teaching the fundamental concepts of evidence-based veterinary medicine (EBV... Read More about Promoting Evidence-based Veterinary Medicine through the online resource ‘EBVM Learning’: User feedback.

Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs (2021)
Journal Article
Spada, S., England, G. C. W., Vignoli, M., Carluccio, A., & Russo, M. (2021). Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs. Animals, 11(2), Article 559. https://doi.org/10.3390/ani11020559

Prostatic neoplasia (PN) occurs in 5–7% of dogs with prostatic disease, with castrated dogs having the same or higher prevalence when compared to intact dogs. Considering the promising results achieved by performing contrast-enhanced ultrasound (CEUS... Read More about Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs.

Homeless people and their dogs: Exploring the nature and impact of the human-companion animal bond (2021)
Journal Article
Scanlon, L., Hobson-West, P., Cobb, K., McBride, A., & Stavisky, J. (2021). Homeless people and their dogs: Exploring the nature and impact of the human-companion animal bond. Anthrozoös, 34(1), 77-92. https://doi.org/10.1080/08927936.2021.1878683

Homelessness is a pervasive social issue worldwide. In the UK, it is currently estimated that one in two hundred people are homeless, approximating 0.5% of the population. Pet ownership among this group is thought to be commonplace and has been linke... Read More about Homeless people and their dogs: Exploring the nature and impact of the human-companion animal bond.

A host-independent role for Fasciola hepatica transforming growth factor-like molecule in parasite development (2021)
Journal Article
Musah-Eroje, M., Hoyle, R. C., Japa, O., Hodgkinson, J. E., Haig, D. M., & Flynn, R. J. (2021). A host-independent role for Fasciola hepatica transforming growth factor-like molecule in parasite development. International Journal for Parasitology, 51(6), 481-492. https://doi.org/10.1016/j.ijpara.2020.11.005

The trematode parasite Fasciola hepatica causes chronic infection in hosts, enabled by an immunosuppressed environment. Both host and parasite factors are known to contribute to this suggesting that avoidance of immunopathology is beneficial to both... Read More about A host-independent role for Fasciola hepatica transforming growth factor-like molecule in parasite development.

Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8+ T-Killers to Kill Human Triple Negative Breast Cancer Cells (2021)
Journal Article
Chulpanova, D. S., Gilazieva, Z. E., Kletukhina, S. K., Aimaletdinov, A. M., Garanina, E. E., James, V., …Solovyeva, V. V. (2021). Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8+ T-Killers to Kill Human Triple Negative Breast Cancer Cells. Biology, 10(2), Article 141. https://doi.org/10.3390/biology10020141

Interleukin 2 (IL2) was one of the first cytokines used for cancer treatment due to its ability to stimulate anti-cancer immunity. However, recombinant IL2-based therapy is associated with high systemic toxicity and activation of regulatory T-cells,... Read More about Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8+ T-Killers to Kill Human Triple Negative Breast Cancer Cells.

Bacteriophages as Bio-sanitizers in Food Production and Healthcare Settings (2021)
Book Chapter
Bhandare, S., & Goodridge, L. (2021). Bacteriophages as Bio-sanitizers in Food Production and Healthcare Settings. In D. R. Harper, S. T. Abedon, B. H. Burrowes, & M. L. McConville (Eds.), Bacteriophages: Biology, Technology, Therapy (769-788). Springer International Publishing. https://doi.org/10.1007/978-3-319-41986-2_26

Sanitization is defined as the removal of soil deposits and subsequent application of a sanitizer or disinfectant to reduce the number of residual microorganisms remaining in an environment. Sanitization may be achieved through use of physical (therm... Read More about Bacteriophages as Bio-sanitizers in Food Production and Healthcare Settings.

Cross?sectional study of UK horse owner's purchase and euthanasia decision?making for their horse (2021)
Journal Article
Clough, H., Roshier, M., England, G., Burford, J., & Freeman, S. (2021). Cross?sectional study of UK horse owner's purchase and euthanasia decision?making for their horse. Veterinary Record, 188(6), Article e56. https://doi.org/10.1002/vetr.56

Background: This cross-sectional study aimed to investigate factors affecting horse owners’ purchase and euthanasia decisions that had been identified in a qualitative study. Methods: An online survey on horse owners’ purchase and euthanasia decisi... Read More about Cross?sectional study of UK horse owner's purchase and euthanasia decision?making for their horse.

Lameness Detection in Cows Using Hierarchical Deep Learning and Synchrosqueezed Wavelet Transform (2021)
Journal Article
Jarchi, D., Kaler, J., & Sanei, S. (2021). Lameness Detection in Cows Using Hierarchical Deep Learning and Synchrosqueezed Wavelet Transform. IEEE Sensors Journal, 21(7), 9349-9358. https://doi.org/10.1109/JSEN.2021.3054718

Objectives: Identification of cow lameness is important to farmers to improve and manage cattle health and welfare. No validated tools exist for automatic lameness detection. In this research, we aim to early detect the cow lameness by identifying th... Read More about Lameness Detection in Cows Using Hierarchical Deep Learning and Synchrosqueezed Wavelet Transform.

1001 MCQs for Parasitology Trainees: The Essential Revision Guide (2021)
Book
Elsheikha, H. (2021). 1001 MCQs for Parasitology Trainees: The Essential Revision Guide. Para Publishing Limited

With a broad range of 1001 multiple choice questions and answers, this book is the ideal resource for all parasitology trainees who need to revise and prepare for parasitology examinations. The questions are representative of curricula of veterinary... Read More about 1001 MCQs for Parasitology Trainees: The Essential Revision Guide.

Predatory bacteria as living antibiotics – where are we now? (2021)
Journal Article
Atterbury, R. J., & Tyson, J. (2021). Predatory bacteria as living antibiotics – where are we now?. Microbiology, 167(1), Article 001025. https://doi.org/10.1099/mic.0.001025

Antimicrobial resistance (AMR) is a global health and economic crisis. With too few antibiotics in development to meet current and anticipated needs, there is a critical need for new therapies to treat Gram-negative infections. One potential approach... Read More about Predatory bacteria as living antibiotics – where are we now?.

Thiamethoxam exposure deregulates short ORF gene expression in the honey bee and compromises immune response to bacteria (2021)
Journal Article
Decio, P., Ustaoglu, P., Derecka, K., Hardy, I. C. W., Roat, T. C., Malaspina, O., …Soller, M. (2021). Thiamethoxam exposure deregulates short ORF gene expression in the honey bee and compromises immune response to bacteria. Scientific Reports, 11(1), Article 1489. https://doi.org/10.1038/s41598-020-80620-7

© 2021, The Author(s). Maximizing crop yields relies on the use of agrochemicals to control insect pests. One of the most widely used classes of insecticides are neonicotinoids that interfere with signalling of the neurotransmitter acetylcholine, but... Read More about Thiamethoxam exposure deregulates short ORF gene expression in the honey bee and compromises immune response to bacteria.

Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers (2021)
Journal Article
Alblihy, A., Alabdullah, M. L., Ali, R., Algethami, M., Toss, M. S., Mongan, N. P., …Madhusudan, S. (2021). Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers. Biomedicines, 9(1), Article 56. https://doi.org/10.3390/biomedicines9010056

Platinum resistance seriously impacts on the survival outcomes of patients with ovarian cancers. Platinum-induced DNA damage is processed through DNA repair. NBS1 is a key DNA repair protein. Here, we evaluated the role of NBS1 in ovarian cancers. NB... Read More about Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers.

Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain (2021)
Journal Article
Zhang, X., Pu, J., Sun, Y., Bi, Y., Jiang, Z., Xu, G., …Sun, H. (2021). Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain. Journal of Virology, 95(7), https://doi.org/10.1128/JVI.01272-20

Avian influenza viruses (AIVs) are zoonotic viruses that exhibit a range infectivity and severity in the human host. Severe human cases of AIVs infection are often accompanied by neurological symptoms, however, the factors involved in the infection o... Read More about Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain.

The microbiological testing regulations for cannabis products in Canada: Are they enough from food safety and public health point of view? (2020)
Journal Article
Sudhakar Bhandare. (2020). The microbiological testing regulations for cannabis products in Canada: Are they enough from food safety and public health point of view?. Journal of Food, Agriculture and Environment, 18(2), 42-44. https://doi.org/10.1234/4.2020.5672

Canada has recently legalised cannabis for its production, sale and usage in various ways viz. medicinal, recreational and edible. The Access to Cannabis for Medical Purposes Regulations (ACMPR) suggests that the microbial and chemical contaminants o... Read More about The microbiological testing regulations for cannabis products in Canada: Are they enough from food safety and public health point of view?.

The ITIM-Containing Receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) Modulates Immune Response and Confers Poor Prognosis in Invasive Breast Carcinoma (2020)
Journal Article
Joseph, C., Alsaleem, M. A., Toss, M. S., Kariri, Y. A., Althobiti, M., Alsaeed, S., …Rakha, E. A. (2020). The ITIM-Containing Receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) Modulates Immune Response and Confers Poor Prognosis in Invasive Breast Carcinoma. Cancers, 13(1), 1-19. https://doi.org/10.3390/cancers13010080

Background: The leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) plays a role in immune response homeostasis, extracellular matrix remodelling and it is overexpressed in many high-grade cancers. This study aimed to elucidate the biologica... Read More about The ITIM-Containing Receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) Modulates Immune Response and Confers Poor Prognosis in Invasive Breast Carcinoma.

RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers (2020)
Journal Article
Alblihy, A., Alabdullah, M. L., Toss, M. S., Algethami, M., Mongan, N. P., Rakha, E. A., & Madhusudan, S. (2020). RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers. Molecular Biomedicine, 1(1), Article 19. https://doi.org/10.1186/s43556-020-00023-y

Intrinsic or acquired resistance seriously limits the use of platinating agents in advanced epithelial ovarian cancers. Increased DNA repair capacity is a key route to platinum resistance. RAD50 is a critical component of the MRN complex, a ‘first re... Read More about RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers.

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study (2020)
Journal Article
Blake, H., Corner, J., Cirelli, C., Hassard, J., Briggs, L., Daly, J. M., …Ball, J. (2021). Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study. International Journal of Environmental Research and Public Health, 18(1), 1-26. https://doi.org/10.3390/ijerph18010188

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. We aimed to explore student and staff perceptions and experiences of a pilot SARS-CoV-2 asymptomatic testing service (P-ATS) in a UK university campus setting. This was a mixed-method study co... Read More about Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study.