Skip to main content

Research Repository

Advanced Search

All Outputs (960)

Association Between Nocturnal Sleep Duration and Obesity Indicators Among People with Type 2 Diabetes: A Cross-Sectional Study in Ningbo, China (2022)
Journal Article

Aim: The study aimed to investigate the association between the nocturnal sleep duration and five obesity indicators, namely, visceral fat area (VFA), subcutaneous fat area (SFA), bodyweight, body mass index (BMI) and waist circumference (WC), among... Read More about Association Between Nocturnal Sleep Duration and Obesity Indicators Among People with Type 2 Diabetes: A Cross-Sectional Study in Ningbo, China.

Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study) (2022)
Journal Article

Introduction It is unknown if a temporary break in long-term immune-suppressive treatment after vaccination against COVID-19 improves vaccine response. The objective of this study was to evaluate if a 2-week interruption in low-dose weekly methotrexa... Read More about Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study).

Feasibility Trial of Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP) among High-Risk People in India: A Qualitative Study to Explore Participants’ Trial- and Intervention-Related Barriers and Facilitators (2022)
Journal Article

Yoga-based interventions can be effective in preventing type 2 diabetes mellitus (T2DM). We developed a Yoga programme for T2DM prevention (YOGA-DP) and conducted a feasibility randomised controlled trial (RCT) among high-risk people in India. This q... Read More about Feasibility Trial of Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP) among High-Risk People in India: A Qualitative Study to Explore Participants’ Trial- and Intervention-Related Barriers and Facilitators.

Trends in indirect liver function marker testing in Wales from 2000 to 2017 and their association with age and sex: An observational study (2022)
Journal Article

Objective If non-invasive markers of liver fibrosis were recorded frequently enough in clinical practice, it might be feasible to use them for opportunistic community screening for liver disease. We aimed to determine their current pattern of usage i... Read More about Trends in indirect liver function marker testing in Wales from 2000 to 2017 and their association with age and sex: An observational study.

Human judgement forecasting tournaments: A feasibility study based on the COVID-19 pandemic with public health practitioners in England (2022)
Journal Article

Objectives: To explore the viability of running human judgement forecasting tournaments with public health practitioners, and to gather initial data on forecasting accuracy and participant perceptions of forecasting. Study design: Quality improvement... Read More about Human judgement forecasting tournaments: A feasibility study based on the COVID-19 pandemic with public health practitioners in England.

The risk of unexpected hospital admissions and primary care visits after an elective day-case gastroscopy: A cohort study within England (2022)
Journal Article

Aim: To determine the excess of acute medical contacts following a day-case diagnostic gastroscopy. Methods: Cohort study using English linked primary, secondary care and death registry electronic health data. We included 277,535 diagnostic day-case... Read More about The risk of unexpected hospital admissions and primary care visits after an elective day-case gastroscopy: A cohort study within England.

COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis (2022)
Journal Article

Objectives: The objectives of this study were to investigate the incidence of COVID-19 hospitalization in unvaccinated and vaccinated patients with RA compared with matched controls, and in patients with RA according to DMARD treatment. Methods: T... Read More about COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis.

Are E-cigarettes associated with postpartum return to smoking? Secondary analyses of a UK pregnancy longitudinal cohort (2022)
Journal Article

Objectives: Postpartum return to smoking (PPRS) is an important public health problem. E-cigarette (EC) use has increased in recent years, and in a contemporary UK pregnancy cohort, we investigated factors, including ECs use, associated with PPRS.... Read More about Are E-cigarettes associated with postpartum return to smoking? Secondary analyses of a UK pregnancy longitudinal cohort.

Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial. (2022)
Journal Article

Objectives: To evaluate the persistence of immunogenicity three months after third dose boosters. Methods: COV-BOOST is a multicentre, randomised, controlled, phase 2 trial of seven COVID-19 vaccines used as a third booster dose. The analysis was con... Read More about Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial..

Are people with mesothelioma who respond to the English Cancer Patient Experience Survey representative of the national mesothelioma population? A data comparison with cancer registry patients from the National Lung Cancer Audit (2022)
Journal Article

Introduction: More than 2,700 people are diagnosed with mesothelioma each year in the UK. Survival from mesothelioma is poor and to ensure service users’ perspectives are incorporated in designing the most effective strategies to improve healthcare i... Read More about Are people with mesothelioma who respond to the English Cancer Patient Experience Survey representative of the national mesothelioma population? A data comparison with cancer registry patients from the National Lung Cancer Audit.

Temporal trends in the incidence of haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003-2018 (2022)
Working Paper

Background Haemophagocytic lymphohistiocytosis (HLH) is rare, results in high mortality and is increasingly being diagnosed. Little is known about what is driving the apparent rise in the incidence of this disease. Methods Using national linked el... Read More about Temporal trends in the incidence of haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003-2018.

Content, Structure, and Delivery Characteristics of Yoga Interventions for Managing Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2022)
Journal Article

Objectives: This systematic review aimed to synthesize the content, structure, and delivery characteristics of effective yoga interventions used for managing hypertension and to compare these characteristics with ineffective interventions. Design and... Read More about Content, Structure, and Delivery Characteristics of Yoga Interventions for Managing Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England (2022)
Journal Article

Objective: To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods: A case–control study design was used. We used linked electronic records from primary care, secondary care and Office for National Statis... Read More about Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England.