All Outputs (25)

Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis (2017)
Journal Article
La-Crette, J., Royle, J., Lanyon, P. C., Ferraro, A., Butler, A., & Pearce, F. A. (2018). Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis. Clinical Rheumatology, 37(4), 1085–1090. https://doi.org/10.1007/s10067-017-3944-7

Objectives We aimed to compare risk of death, relapse, neutropenia and infection requiring hospital admission between unselected ANCA-associated vasculitis (AAV) patients according to whether cyclophosphamide induction was by daily oral (PO) or pulse... Read More about Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis.

Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study (2017)
Journal Article
Pearce, F. A., Hubbard, R., Grainge, M. J., Watts, R. A., Abhishek, A., & Lanyon, P. C. (in press). Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study. QJM: An International Journal of Medicine, https://doi.org/10.1093/qjmed/hcx194

Background: People with granulomatosis with polyangiitis (GPA) commonly describe long delays before diagnosis. Aim: To study the natural history of GPA prior to diagnosis using primary care data, and determine whether clinical features could be iden... Read More about Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study.

Global ethnic and geographic differences in the clinical presentations of anti-neutrophil cytoplasm antibody–associated vasculitis (2017)
Journal Article
Pearce, F. A., Craven, A., Merkel, P. A., Luqmani, R. A., & Watts, R. A. (2017). Global ethnic and geographic differences in the clinical presentations of anti-neutrophil cytoplasm antibody–associated vasculitis. Rheumatology, 56(11), 1962-1969. https://doi.org/10.1093/rheumatology/kex293

© The Author 2017. Objectives. There are few data on clinical profiles of ANCA-associated vasculitis (AAV) in different ethnic populations. The aim of this study was to examine the differences in the ANCA type and clinical features of AAV between pop... Read More about Global ethnic and geographic differences in the clinical presentations of anti-neutrophil cytoplasm antibody–associated vasculitis.

The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink (2016)
Journal Article
Pearce, F. A., Grainge, M. J., Lanyon, P. C., Watts, R. A., & Hubbard, R. B. (in press). The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink. Rheumatology, https://doi.org/10.1093/rheumatology/kew413

Objectives: To estimate the incidence, prevalence and mortality of Granulomatosis with polyangiitis (GPA) in the United Kingdom. Methods: We conducted a historical cohort study using data from the Clinical Practice Research Datalink and Hospital Epi... Read More about The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink.

Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population (2016)
Journal Article
Pearce, F. A., Lanyon, P. C., Grainge, M. J., Shaunak, R., Mahr, A., Hubbard, R. B., & Watts, R. A. (in press). Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population. Rheumatology, 55(9), https://doi.org/10.1093/rheumatology/kew232

Objectives: We aimed to estimate the incidence of ANCA-associated vasculitis in the UK and how this varied by ethnic group. Methods: We identified incident cases of ANCA-associated vasculitis between March 2007 and June 2013 in the Nottingham–Derby... Read More about Incidence of ANCA-associated vasculitis in a UK mixed ethnicity population.