All Outputs (7)

COVID-19 and pregnancy: A comparison of case reports, case series and registry studies (2021)
Journal Article
Young, E. M., Green, O., Stewart, J., King, Y., O'Donoghue, K., Walker, K. F., & Thornton, J. G. (2022). COVID-19 and pregnancy: A comparison of case reports, case series and registry studies. European Journal of Obstetrics and Gynecology and Reproductive Biology, 268, 135-142. https://doi.org/10.1016/j.ejogrb.2021.12.002

Background: Selection, outcome and publication biases are well described in case reports and case series but may be less of a problem early in the appearance of a new disease when all cases might appear to be worth publishing. Objective: To use a pro... Read More about COVID-19 and pregnancy: A comparison of case reports, case series and registry studies.

Case of successfully delivered dicavitary twins in uterus didelphus (2021)
Journal Article
Barnes, E., Walker, K., Sayed, H. M., & Green, A. (2021). Case of successfully delivered dicavitary twins in uterus didelphus. BMJ Case Reports, 14(11), e245139. https://doi.org/10.1136/bcr-2021-245139

Uterus didelphus is a congenital abnormality arising from failure of fusion of Mullerian ducts, creating two separate uterine horns, two cervices and, in some cases, a vagina divided by a longitudinal septum. In this case, a 26-year-old woman with pr... Read More about Case of successfully delivered dicavitary twins in uterus didelphus.

Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis (2021)
Journal Article
Giesbers, S., Goh, E., Kew, T., Allotey, J., Brizuela, V., Kara, E., …Mofenson, L. (2021). Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology, 267, 120-128. https://doi.org/10.1016/j.ejogrb.2021.10.007

Objective: Clinical trials evaluating pharmacological and non-pharmacological treatment of COVID-19, either excluded pregnant women or included very few women. Unlike the numerous systematic reviews on prevalence, symptoms and adverse outcomes of COV... Read More about Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis.

Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology (2021)
Journal Article
Venkatanarayanan, N., & Walker, K. F. (2021). Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology. Best Practice and Research: Clinical Obstetrics and Gynaecology, 77, 42-52. https://doi.org/10.1016/j.bpobgyn.2021.08.007

Worldwide, there has been a trend toward later motherhood. Concurrently, the incidence of subfertility has been on the rise, necessitating conception using assisted reproductive technologies (ARTs). These pregnancies are considered high risk due to f... Read More about Evidence around early induction of labor in women of advanced maternal age and those using assisted reproductive technology.

Should all pregnant women be offered testing for group B streptococcus? (2021)
Journal Article
Walker, K. F., Plumb, J., Gray, J., Thornton, J., Avery, A. J., & Daniels, J. P. (2021). Should all pregnant women be offered testing for group B streptococcus?. BMJ, 373, Article n882. https://doi.org/10.1136/bmj.n882

Evaluating the influence of progesterone concentration and time of exposure on in vitro endometrial decidualisation (2021)
Journal Article
Suthaporn, S., Jayaprakasan, K., Thornton, J. G., Walker, K. F., Castellanos, M., May, S., …Maalouf, W. E. (2021). Evaluating the influence of progesterone concentration and time of exposure on in vitro endometrial decidualisation. Molecular and Cellular Endocrinology, 528, Article 111242. https://doi.org/10.1016/j.mce.2021.111242

This study aimed to evaluate the influence of progesterone (concentration and time of exposure) on endometrial decidualisation using an in vitro model cell line: Human Endometrial Stromal Cells (HESCs). HESCs exposed to progesterone (1 and 10 μM) had... Read More about Evaluating the influence of progesterone concentration and time of exposure on in vitro endometrial decidualisation.

The challenges of randomised control trials in obstetrics and gynaecology (2021)
Journal Article
Harper, S. L., Thornton, J. G., & Walker, K. F. (2021). The challenges of randomised control trials in obstetrics and gynaecology. Obstetrics, Gynaecology and Reproductive Medicine, 31(2), 59-60. https://doi.org/10.1016/j.ogrm.2020.12.006

In this short article we explore some of the challenges faced by those conducting randomised trials in obstetrics and gynaecology. We discuss the current status of trials comparing induction of labour versus expectant management, so called ‘deliver o... Read More about The challenges of randomised control trials in obstetrics and gynaecology.