All Outputs (139)

The attitudes of owners and veterinary professionals in the United Kingdom to the risk of adverse events associated with using non- steroidal anti-inflammatory drugs (NSAIDs) to treat dogs with osteoarthritis (2016)
Journal Article
Belshaw, Z., Asher, L., & Dean, R. S. (2016). The attitudes of owners and veterinary professionals in the United Kingdom to the risk of adverse events associated with using non- steroidal anti-inflammatory drugs (NSAIDs) to treat dogs with osteoarthritis. Preventive Veterinary Medicine, 131, 121-126. https://doi.org/10.1016/j.prevetmed.2016.07.017

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed by veterinary surgeons for the treatment of canine osteoarthritis, and affected dogs may receive these drugs for long periods of time. Whilst short term administration of NSAIDs t... Read More about The attitudes of owners and veterinary professionals in the United Kingdom to the risk of adverse events associated with using non- steroidal anti-inflammatory drugs (NSAIDs) to treat dogs with osteoarthritis.

Assessment of acute pain in cats: signs, tools and limitations (2016)
Journal Article
L White, K. (2017). Assessment of acute pain in cats: signs, tools and limitations. Companion Animal, 21(8), 458-465. https://doi.org/10.12968/coan.2016.21.8.458

Recent advances in pain assessment in companion animals represent a tenacious, painstaking and time-consuming dedication to improving animal welfare. Attitudes and knowledge about pain assessment, particularly in cats, have changed dramatically in th... Read More about Assessment of acute pain in cats: signs, tools and limitations.

High throughput method for analysis of repeat number for 28 phase variable loci of C. jejuni strain NCTC11168 (2016)
Journal Article
Lango-Scholey, L., Aidley, J., Woodacre, A., Jones, M. A., & Bayliss, C. D. (2016). High throughput method for analysis of repeat number for 28 phase variable loci of C. jejuni strain NCTC11168. PLoS ONE, 11(7), 1-15. https://doi.org/10.1371/journal.pone.0159634

Mutations in simple sequence repeat tracts are a major mechanism of phase variation in several bacterial species including Campylobacter jejuni. Changes in repeat number of tracts located within the reading frame can produce a high frequency of rever... Read More about High throughput method for analysis of repeat number for 28 phase variable loci of C. jejuni strain NCTC11168.

International evidence-based medicine survey of the veterinary profession: information sources used by veterinarians (2016)
Journal Article
Huntley, S. J., Dean, R. S., Massey, A., & Brennan, M. L. (2016). International evidence-based medicine survey of the veterinary profession: information sources used by veterinarians. PLoS ONE, 11(7), 1-18. https://doi.org/10.1371/journal.pone.0159732

Veterinarians are encouraged to use evidence to inform their practice, but it is unknown what resources (e.g. journals, electronic sources) are accessed by them globally. Understanding the key places veterinarians seek information can inform where ne... Read More about International evidence-based medicine survey of the veterinary profession: information sources used by veterinarians.

Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK (2016)
Journal Article
Welsh, C. E., Duz, M., Parkin, T. D., & Marshall, J. F. (2016). Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK. Preventive Veterinary Medicine, 131, https://doi.org/10.1016/j.prevetmed.2016.07.011

he average age of the global human population is increasing, leading to increased interest in the effects of chronic disease and multimorbidity on health resources and patient welfare. It has been posited that the average age of the general veterinar... Read More about Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK.

Factors influencing common diagnoses made during first-opinion small-animal consultations in the United Kingdom (2016)
Journal Article
Robinson, N., Dean, R. S., Cobb, M., & Brennan, M. L. (2016). Factors influencing common diagnoses made during first-opinion small-animal consultations in the United Kingdom. Preventive Veterinary Medicine, 131, 87-94. https://doi.org/10.1016/j.prevetmed.2016.07.014

It is currently unclear how frequently a diagnosis is made during small-animal consultations or how much of a role making a diagnosis plays in veterinary decision-making. Understanding more about the diagnostic process will help direct future researc... Read More about Factors influencing common diagnoses made during first-opinion small-animal consultations in the United Kingdom.

Rabies outbreak in Greece during 2012–2014: use of Geographical Information System for analysis, risk assessment and control (2016)
Journal Article
Giannakopoulos, A., Valiakos, G., Papaspyropoulos, K., Dougas, G., Korou, L. M., Tasioudi, K. E., …Billinis, C. (2016). Rabies outbreak in Greece during 2012–2014: use of Geographical Information System for analysis, risk assessment and control. Epidemiology and Infection, 144(14), https://doi.org/10.1017/S0950268816001527

The objectives of this work were (i) geographical analysis of the 2012–2014 outbreak of rabies in Greece using GIS and (ii) comparative analysis of animal cases with data of potential human exposure to rabies together with environmental data, in orde... Read More about Rabies outbreak in Greece during 2012–2014: use of Geographical Information System for analysis, risk assessment and control.

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice (2016)
Journal Article
Poissonnier, A., Sanséau, D., Le Gallo, M., Malleter, M., Levoin, N., Viel, R., …Legembre, P. (2016). CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. Immunity, 45(1), 209-223. https://doi.org/10.1016/j.immuni.2016.06.028

CD95 ligand (CD95L) is expressed by immune cells and triggers apoptotic death. Metalloprotease-cleaved CD95L (cl-CD95L) is released into the bloodstream but does not trigger apoptotic signaling. Hence, the pathophysiological role of cl-CD95L remains... Read More about CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.

RNA expression of TLR10 in normal equine tissues (2016)
Journal Article
Tarlinton, R. E., Alder, L., Moreton, J., Maboni, G., Emes, R. D., & Tötemeyer, S. (2016). RNA expression of TLR10 in normal equine tissues. BMC Research Notes, 9, Article 353. https://doi.org/10.1186/s13104-016-2161-9

Background: Toll like receptors are one of the major innate immune system pathogen recognition systems. There is little data on the expression of the TLR10 member of this family in the horse. Results: This paper describes the genetic structure of... Read More about RNA expression of TLR10 in normal equine tissues.

Incomplete ovarian tissue removal in female dogs and cats (2016)
Journal Article
England, G. C., & White, R. (2016). Incomplete ovarian tissue removal in female dogs and cats. In Practice, 38(7), 315-326. https://doi.org/10.1136/inp.i3356

Incomplete ovariectomy (IO) is the unintentional partial or complete lack of removal of one or both ovaries during an ovariohysterectomy or ovariectomy procedure, and is often referred to as ‘ovarian remnant syndrome’. It usually has a clear clinical... Read More about Incomplete ovarian tissue removal in female dogs and cats.

Global iTRAQ-based proteomic profiling of Toxoplasma gondii oocysts during sporulation (2016)
Journal Article
Zhou, C., Zhu, X., Elsheikha, H. M., He, S., Li, Q., Zhou, D., & Suo, X. (2016). Global iTRAQ-based proteomic profiling of Toxoplasma gondii oocysts during sporulation. Journal of Proteomics, 148, 12-19. https://doi.org/10.1016/j.jprot.2016.07.010

Toxoplasma gondii is a medically and economically important protozoan parasite. However, the molecular mechanisms of its sporulation remain largely unknown. Here, we applied iTRAQ coupled with 2D LC–MS/MS proteomic analysis to investigate the proteom... Read More about Global iTRAQ-based proteomic profiling of Toxoplasma gondii oocysts during sporulation.

Updates on feline aelurostrongylosis and research priorities for the next decade (2016)
Journal Article
Elsheikha, H. M., Schnyder, M., Traversa, D., Di Cesare, A., Wright, I., & Lacher, D. W. (2016). Updates on feline aelurostrongylosis and research priorities for the next decade. Parasites and Vectors, 9, https://doi.org/10.1186/s13071-016-1671-6

Feline aelurostrongylosis, caused by the metastrongyloid nematode Aelurostrongylus abstrusus, is an important gastropod-borne parasitic lung disease in cats. Infection with A. abstrusus is widespread globally, but the increasing awareness of this par... Read More about Updates on feline aelurostrongylosis and research priorities for the next decade.

Using combined diagnostic test results to hindcast trends of infection from cross-sectional data (2016)
Journal Article
Rydevik, G., Innocent, G. T., Marion, G., Davidson, R. S., White, P. C., Billinis, C., …Hutchings, M. R. (2016). Using combined diagnostic test results to hindcast trends of infection from cross-sectional data. PLoS Computational Biology, 12(7), 1-19. https://doi.org/10.1371/journal.pcbi.1004901

Infectious disease surveillance is key to limiting the consequences from infectious pathogens and maintaining animal and public health. Following the detection of a disease outbreak, a response in proportion to the severity of the outbreak is require... Read More about Using combined diagnostic test results to hindcast trends of infection from cross-sectional data.

Prevailing PA mutation K356R in avian influenza H9N2 virus increases mammalian replication and pathogenicity (2016)
Journal Article
Xu, G., Zhang, X., Gao, W., Wang, C., Wang, J., Sun, H., …Pu, J. (in press). Prevailing PA mutation K356R in avian influenza H9N2 virus increases mammalian replication and pathogenicity. Journal of Virology, 90(18), https://doi.org/10.1128/JVI.00883-16

Adaptation of the viral polymerase complex comprising PB1, PB2, and PA is necessary for efficient influenza A virus replication in new host species. We found that PA mutation K356R (PA-K356R) has become predominant since 2014 in avian H9N2 viruses in... Read More about Prevailing PA mutation K356R in avian influenza H9N2 virus increases mammalian replication and pathogenicity.

Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth (2016)
Journal Article
Brown, D. M., Williams, H., Ryan, K., Wilson, T., Daniel, Z. C., Mareko, M. H. D., …Parr, T. (2016). Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth. Scientific Reports, 6(1), https://doi.org/10.1038/srep28693

We aimed to identify novel molecular mechanisms for muscle growth during administration of anabolic agents. Growing pigs (Duroc/(Landrace/Large-White)) were administered Ractopamine (a beta-adrenergic agonist; BA; 20 ppm in feed) or Reporcin (recombi... Read More about Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth.

Mitochondrial complex 1 activity measured by spectrophotometry is reduced across all brain regions in ageing and more specifically in neurodegeneration (2016)
Journal Article
Cai, H., Pollard, A. K., Craig, E. L., & Chakrabarti, L. (in press). Mitochondrial complex 1 activity measured by spectrophotometry is reduced across all brain regions in ageing and more specifically in neurodegeneration. PLoS ONE, 11(6), Article e0157405. https://doi.org/10.1371/journal.pone.0157405

Mitochondrial function, in particular complex 1 of the electron transport chain (ETC), has been shown to decrease during normal ageing and in neurodegenerative disease. However, there is some debate concerning which area of the brain has the greatest... Read More about Mitochondrial complex 1 activity measured by spectrophotometry is reduced across all brain regions in ageing and more specifically in neurodegeneration.

Associations between sheep farmer attitudes, beliefs, emotions and personality, and their barriers to uptake of best practice: the example of footrot (2016)
Journal Article
O’Kane, H., Ferguson, E., Kaler, J., & Green, L. (2017). Associations between sheep farmer attitudes, beliefs, emotions and personality, and their barriers to uptake of best practice: the example of footrot. Preventive Veterinary Medicine, 139, 123-133. https://doi.org/10.1016/j.prevetmed.2016.05.009

There is interest in understanding how farmers’ behaviour influences their management of livestock. We extend the theory of planned behaviour with farmers attitudes, beliefs, emotions and personality to investigate how these are associated with manag... Read More about Associations between sheep farmer attitudes, beliefs, emotions and personality, and their barriers to uptake of best practice: the example of footrot.

STAT5 induces miR-21 expression in cutaneous T cell lymphoma (2016)
Journal Article
Lindahl, L. M., Fredholm, S., Joseph, C., Nielsen, B. S., Jønson, L., Willerslev-Olsen, A., …Odum, N. (2016). STAT5 induces miR-21 expression in cutaneous T cell lymphoma. Oncotarget, https://doi.org/10.18632/oncotarget.10160

In cutaneous T cell lymphomas (CTCL), miR-21 is aberrantly expressed in skin and peripheral blood and displays anti-apoptotic properties in malignant T cells. It is, however, unclear exactly which cells express miR-21 and what mechanisms regulate miR... Read More about STAT5 induces miR-21 expression in cutaneous T cell lymphoma.

Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle (2016)
Journal Article
Swift, B. M., Huxley, J., Plain, K. M., Begg, D. J., de Silva, K., Purdie, A. C., …Rees, C. (2016). Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle. BMC Veterinary Research, 12, Article 115. https://doi.org/10.1186/s12917-016-0728-2

Background Disseminated infection and bacteraemia is an underreported and under-researched aspect of Johne’s disease. This is mainly due to the time it takes for Mycobacterium avium subsp. paratuberculosis (MAP) to grow and lack of sensitivity of... Read More about Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle.

Factors associated with the presence and prevalence of contagious ovine digital dermatitis: a 2013 study of 1136 random English sheep flocks (2016)
Journal Article
Dickins, A., Clark, C. C., Kaler, J., Ferguson, E., O’Kane, H., & Green, L. E. (2016). Factors associated with the presence and prevalence of contagious ovine digital dermatitis: a 2013 study of 1136 random English sheep flocks. Preventive Veterinary Medicine, 130, https://doi.org/10.1016/j.prevetmed.2016.06.009

In 2013, a questionnaire was used to gather data on risks for introduction, and factors associated with prevalence, of contagious ovine digital dermatitis (CODD). There were 1136 (28.4%) usable responses from 4000 randomly selected sheep farmers in E... Read More about Factors associated with the presence and prevalence of contagious ovine digital dermatitis: a 2013 study of 1136 random English sheep flocks.