All Outputs (105)

Efficacy of progesterone supplementation during early pregnancy in cows: a meta-analysis (2015)
Journal Article

Progesterone is a critical hormone during early pregnancy in the cow. As a result, a number of studies have investigated the effects of progesterone supplementation on pregnancy rates. In this study, a meta-analysis using a univariate binary random e... Read More about Efficacy of progesterone supplementation during early pregnancy in cows: a meta-analysis.

Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages (2015)
Journal Article

The etiology of multiple sclerosis (MS) is still unknown, but there is strong evidence that genetic predisposition associated with environmental factors can trigger the disease. An estimated 30 million years ago, exogenous retroviruses are thought to... Read More about Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages.

Oral vaccination with a rough attenuated mutant of S. Infantis increases post-wean weight gain and prevents clinical signs of salmonellosis in S. Typhimurium challenged pigs (2015)
Journal Article

We show that oral inoculation of 14 day old conventional piglets with a rough attenuated Salmonella enterica serovar Infantis 1326/28?r (serogroup C1), 24 h prior to oral challenge with S. enterica serovar Typhimurium 4/74 (serogroup B), resulted in... Read More about Oral vaccination with a rough attenuated mutant of S. Infantis increases post-wean weight gain and prevents clinical signs of salmonellosis in S. Typhimurium challenged pigs.

Investigating preventive-medicine consultations in first-opinion small-animal practice in the United Kingdom using direct observation (2015)
Journal Article

Preventive-medicine consultations account for a large proportion of the veterinary caseload and previous research has suggested these consultations are fundamentally different from those in which the animal is presented for a specific health problem.... Read More about Investigating preventive-medicine consultations in first-opinion small-animal practice in the United Kingdom using direct observation.

Modulation of potassium channels inhibits bunyavirus infection (2015)
Journal Article

Bunyaviruses are considered to be emerging pathogens facilitated by the segmented nature of their genome that allows reassortment between different species to generate novel viruses with altered pathogenicity. Bunyaviruses are transmitted via a diver... Read More about Modulation of potassium channels inhibits bunyavirus infection.

Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring (2015)
Journal Article

© Copyright 2015 The Authors. The Western diet is typically high in salt and fructose, which have pressor activity. Maternal diet can affect offspring blood pressure, but the extent to which maternal intake of excess salt and fructose may influence c... Read More about Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring.

The effect of paratuberculosis on milk yield—a systematic review and meta-analysis (2015)
Journal Article

Bovine paratuberculosis is a disease characterized by chronic granulomatous enteritis causing protein-losing enteropathy. Adverse effects on animal productivity are key drivers in the attempt to control paratuberculosis at the farm level. Economic mo... Read More about The effect of paratuberculosis on milk yield—a systematic review and meta-analysis.

Alcelaphine herpesvirus 1 glycoprotein B: recombinant expression and antibody recognition (2015)
Journal Article

The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes fatal malignant catarrhal fever (MCF) in susceptible species including cattle, but infects its reservoir host, wildebeest, without causing disease. Pathology in cattle may be influenced b... Read More about Alcelaphine herpesvirus 1 glycoprotein B: recombinant expression and antibody recognition.

Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation (2015)
Journal Article

Pigs are evidently more resistant to avian than swine influenza A viruses, mediated in part through frontline epithelial cells and alveolar macrophages (AM). Although porcine AM (PAM) are crucial in influenza virus control, their mode of control is u... Read More about Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation.

Sequence and partial functional analysis of canine Bcl-2 family proteins (2015)
Journal Article

Dogs present with spontaneous neoplasms biologically similar to human cancers. Apoptotic pathways are deregulated during cancer genesis and progression and are important for therapy. We have assessed the degree of conservation of a set of canine Bcl-... Read More about Sequence and partial functional analysis of canine Bcl-2 family proteins.

Test-retest reliability and predictive validity of a juvenile guide dog behavior test (2015)
Journal Article

The ability to measure stable and consistent behavioral traits in dogs would facilitate selection and assessment of working dogs, such as guide dogs. Ideally, these measures should predict suitability for the working role from a young age. This study... Read More about Test-retest reliability and predictive validity of a juvenile guide dog behavior test.

Methods for differentiating prion types in food-producing animals (2015)
Journal Article

Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by the conformation of the disease form of the prion protein (PrPSc). Prion diseases affect hum... Read More about Methods for differentiating prion types in food-producing animals.

Liver copper concentrations in cull cattle in the UK: are cattle being copper loaded? (2015)
Journal Article

With the release of the Department for the Environment, Food and Rural Affairs/Advisory Committee on Animal Feed Guidance Note for Supplementing Copper to Bovines it was noted that the current copper status of the national herd was not known. Liver s... Read More about Liver copper concentrations in cull cattle in the UK: are cattle being copper loaded?.

Using the incidence and impact of health conditions in guide dogs to investigate healthy ageing in working dogs (2015)
Journal Article

This study aimed to use retirement data from working guide dogs to investigate healthy ageing in dogs and the demographic factors that influence ageing. Using a dataset of 7686 dogs spanning 20 years, dogs withdrawn for health reasons before they rea... Read More about Using the incidence and impact of health conditions in guide dogs to investigate healthy ageing in working dogs.

Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes (2015)
Journal Article

AIM: Although aberrant DNA methylation has been described in rheumatoid arthritis (RA), no studies have interrogated this epigenetic modification in early disease. Following recent investigations of T- and B-lymphocytes in established disease, we now... Read More about Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes.

The impact of early postnatal environmental enrichment on maternal care and offspring behaviour following weaning (2015)
Journal Article

The early postnatal period is a sensitive period in rodents as behavioural systems are developing and maturing during this time. However, relatively little information is available about the impact of environmental enrichment on offspring behaviour i... Read More about The impact of early postnatal environmental enrichment on maternal care and offspring behaviour following weaning.

Farmers’ perception of the role of veterinary surgeons in vaccination strategies on British dairy farms (2015)
Journal Article

There is limited research investigating the motivators and barriers to vaccinating dairy cattle. Veterinary surgeons have been identified as important sources of information for farmers making vaccination and disease control decisions, as well as bei... Read More about Farmers’ perception of the role of veterinary surgeons in vaccination strategies on British dairy farms.

Micronutrient and amino acid losses in acute renal replacement therapy (2015)
Journal Article

A wide range of renal replacement therapies is now available to support patients with acute kidney injury. These treatments utilize diffusion, convection or a combination of these mechanisms to remove metabolic waste products from the bloodstream. It... Read More about Micronutrient and amino acid losses in acute renal replacement therapy.

Clinical audit in veterinary practice: theory v reality (2015)
Journal Article

CLINICAL AUDIT is an effective tool for assessing and improving the clinical care provided to patients. Good guidance has previously been provided in the veterinary literature as to how to conduct clinical audit in veterinary practice (Mosedale 1998,... Read More about Clinical audit in veterinary practice: theory v reality.

We need to talk about error: causes and types of error in veterinary practice (2015)
Journal Article

Patient safety research in human medicine has identified the causes and common types of medical error and subsequently informed the development of interventions which mitigate harm, such as the WHO’s safe surgery checklist. There is no such evidence... Read More about We need to talk about error: causes and types of error in veterinary practice.