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Neuroaxonal dystrophy in a flock of pied imperial pigeons (Ducula bicolor) (2017)
Journal Article
Barrows, M., Killick, R., Day, C., Saunders, R., Baiker, K., Ressel, L., & Denk, D. (2017). Neuroaxonal dystrophy in a flock of pied imperial pigeons (Ducula bicolor). Journal of Comparative Pathology, 156(4), 451-457. https://doi.org/10.1016/j.jcpa.2017.02.006

Five juvenile pied imperial pigeons (Ducula bicolor) presented with neurological signs including torticollis, ataxia and poor flying ability. All were humanely destroyed and submitted for post-mortem examination. Microscopically, the most significant... Read More about Neuroaxonal dystrophy in a flock of pied imperial pigeons (Ducula bicolor).

A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity (2017)
Journal Article
Afonso, M. M., Pinchbeck, G. L., Smith, S. L., Daly, J. M., Gaskell, R. M., Dawson, S., & Radford, A. D. (2017). A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity. Vaccine, 35(20), 2753-2760. https://doi.org/10.1016/j.vaccine.2017.03.030

Background Feline calicivirus (FCV) is an important pathogen of cats for which vaccination is regularly practised. Long-term use of established vaccine antigens raises the theoretical possibility that field viruses could become resistant. This stu... Read More about A multi-national European cross-sectional study of feline calicivirus epidemiology, diversity and vaccine cross-reactivity.

Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations (2017)
Journal Article
Aidley, J. B., Rajopadhye, S., Akinyemi, N., Lango-Scholey, L., Jones, M. A., & Bayliss, C. D. (2017). Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations. mBio, 8(2), 1-14. https://doi.org/10.1128/mBio.02311-16

Phase variation occurs in many pathogenic and commensal bacteria and is a major generator of genetic variability. A putative advantage of phase variation is to counter reductions in variability imposed by nonselective bottlenecks during transmission.... Read More about Nonselective Bottlenecks Control the Divergence and Diversification of Phase-Variable Bacterial Populations.

Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells (2017)
Journal Article
Werling, D., Hope, J. C., Siddiqui, N., Widdison, S., Russell, C., Sopp, P., & Coffey, T. J. (2017). Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells. Frontiers in Veterinary Science, 4, Article 44. https://doi.org/10.3389/fvets.2017.00044

Within the ruminant system, several possibilities exist to generate dendritic cells migrating out from the tissue into the regional draining lymph nodes as afferent lymph dendritic cells (ALDCs). Here, we analyzed toll-like receptor (TLR) 1–10 mRNA e... Read More about Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells.

Morphological and structural investigations of Egyptian water buffalo (Bubalus Bubalis) sertoli cells (2017)
Journal Article
Rutland, C. S., Derbalah, A., Karam Roshdy, K., & El-Gendy, S. (2017). Morphological and structural investigations of Egyptian water buffalo (Bubalus Bubalis) sertoli cells. Journal of Buffalo Science, 6(1), https://doi.org/10.6000/1927-520X.2017.06.01.1

Buffaloes are essential part of the economy in many countries and provide sustainable food in addition to being working animals. Inefficiency in reproduction has become problematic in recent years due to a number of factors and although much research... Read More about Morphological and structural investigations of Egyptian water buffalo (Bubalus Bubalis) sertoli cells.

Blood-feeding patterns of native mosquitoes and insights into their potential role as pathogen vectors in the Thames estuary region of the United Kingdom (2017)
Journal Article
Brugman, V. A., Hernández-Triana, L. M., England, M. E., Medlock, J. M., Mertens, P. P., Logan, J. G., …Carpenter, S. (2017). Blood-feeding patterns of native mosquitoes and insights into their potential role as pathogen vectors in the Thames estuary region of the United Kingdom. Parasites and Vectors, 10(1), Article 163. https://doi.org/10.1186/s13071-017-2098-4

Background: The range of vertebrate hosts on which species of mosquito blood-feed is an important parameter for identifying potential vectors and in assessing the risk of incursion and establishment of vector-borne pathogens. In the United Kingdom, s... Read More about Blood-feeding patterns of native mosquitoes and insights into their potential role as pathogen vectors in the Thames estuary region of the United Kingdom.

A distinct bacterial dysbiosis associated skin inflammation in ovine footrot (2017)
Journal Article
Maboni, G., Blanchard, A. M., Frosth, S., Stewart, C. E., Emes, R. D., & Tötemeyer, S. (in press). A distinct bacterial dysbiosis associated skin inflammation in ovine footrot. Scientific Reports, 7, Article 45220. https://doi.org/10.1038/srep45220

Ovine footrot is a highly prevalent bacterial disease caused by Dichelobacter nodosus and characterised by the separation of the hoof horn from the underlying skin. The role of innate immune molecules and other bacterial communities in the developmen... Read More about A distinct bacterial dysbiosis associated skin inflammation in ovine footrot.

Mouse mitochondrial lipid composition is defined by age in brain and muscle (2017)
Journal Article
Pollard, A. K., Ortori, C. A., Stöger, R., Barrett, D. A., & Chakrabarti, L. (in press). Mouse mitochondrial lipid composition is defined by age in brain and muscle. Aging, 9(3), https://doi.org/10.18632/aging.101204

Functionality of the lipid rich mitochondrial organelle declines with increased age. Recent advances in lipidomic technologies allowed us to perform a global characterisation of lipid composition in two different tissue types and age ranges. Ultra-hi... Read More about Mouse mitochondrial lipid composition is defined by age in brain and muscle.

Genomic insights into cardiomyopathies: a comparative cross-species review (2017)
Journal Article
Simpson, S., Rutland, P., & Rutland, C. S. (2017). Genomic insights into cardiomyopathies: a comparative cross-species review. Veterinary Sciences, 4(1), Article 19. https://doi.org/10.3390/vetsci4010019

n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year. This review compares the ca... Read More about Genomic insights into cardiomyopathies: a comparative cross-species review.

De novo transcriptome sequencing and analysis of the juvenile and adult stages of Fasciola gigantica (2017)
Journal Article
Zhang, X.-X., Cong, W., Elsheikha, H. M., Liu, G.-H., Ma, J.-G., Huang, W.-Y., …Zhu, X.-Q. (2017). De novo transcriptome sequencing and analysis of the juvenile and adult stages of Fasciola gigantica. Infection, Genetics and Evolution, 51, 33-40. https://doi.org/10.1016/j.meegid.2017.03.007

Fasciola gigantica is regarded as the major liver fluke causing fasciolosis in livestock in tropical countries. Despite the significant economic and public health impacts of F. gigantica there are few studies on the pathogenesis of this parasite and... Read More about De novo transcriptome sequencing and analysis of the juvenile and adult stages of Fasciola gigantica.

The awareness of the international veterinary profession of evidence-based veterinary medicine and preferred methods of training (2017)
Journal Article
Huntley, S. J., Dean, R. S., & Brennan, M. L. (2017). The awareness of the international veterinary profession of evidence-based veterinary medicine and preferred methods of training. Veterinary Sciences, 4(1), Article 15. https://doi.org/10.3390/vetsci4010015

Evidence-based veterinary medicine (EVM) is an evolving discipline in veterinary medicine so it is important to periodically “benchmark” opinion about EVM across the profession. An international survey to assess veterinarians’ awareness of EVM was co... Read More about The awareness of the international veterinary profession of evidence-based veterinary medicine and preferred methods of training.

Evaluating veterinary practitioner perceptions of communication skills and training (2017)
Journal Article
McDermott, M., Cobb, M., Tischler, V., Robbé, I., & Dean, R. S. (2017). Evaluating veterinary practitioner perceptions of communication skills and training. Veterinary Record, 180(12), https://doi.org/10.1136/vr.103997

A survey was conducted among veterinary practitioners in the UK and the USA in 2012/2013. Thematic analysis was used to identify underlying reasons behind answers to questions about the importance of communication skills and the desire to participate... Read More about Evaluating veterinary practitioner perceptions of communication skills and training.

Clinical comparison of alfaxalone, ketamine and propofol following medetomidine and methadone in dogs (2017)
Journal Article
White, K. L., & Yates, D. (in press). Clinical comparison of alfaxalone, ketamine and propofol following medetomidine and methadone in dogs. Veterinary Anaesthesia and Analgesia, https://doi.org/10.1016/j.vaa.2016.12.057

Objective To compare the clinical effects of alfaxalone, ketamine and propofol in dogs following premedication with medetomidine and methadone. Study design Prospective, ‘blinded’ and randomized clinical study. Animals A total of 75 ma... Read More about Clinical comparison of alfaxalone, ketamine and propofol following medetomidine and methadone in dogs.

Evolution of complexity in the zebrafish synapse proteome (2017)
Journal Article
Bayés, À., Bayes, A., Collins, M. O., Reig-Vader, R., Gou, G., Goulding, D., …Grant, S. G. (in press). Evolution of complexity in the zebrafish synapse proteome. Nature Communications, 8, Article 14613. https://doi.org/10.1038/ncomms14613

The proteome of human brain synapses is highly complex and mutated in over 130 diseases. This complexity arose from two whole genome duplications early in the vertebrate lineage. Zebrafish are used in modelling human diseases, however its synapse pro... Read More about Evolution of complexity in the zebrafish synapse proteome.

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development (2017)
Journal Article
Metzler, V. M., de Brot, S., Robinson, R. S., Jeyapalan, J. N., Rakha, E., Walton, T., …Mongan, N. P. (2017). Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development. Placenta, 56, 79-85. https://doi.org/10.1016/j.placenta.2017.02.018

The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy,... Read More about Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development.

Mineral status in canine medial coronoid process disease: a cohort study using analysis of hair by mass spectrometry (2017)
Journal Article
Davies, M., West, J., Williams, C., & Gardner, D. S. (in press). Mineral status in canine medial coronoid process disease: a cohort study using analysis of hair by mass spectrometry. Veterinary Record, 180(18), https://doi.org/10.1136/vr.103953

In several species, developmental skeletal diseases involving abnormal endochondral ossification have been associated with imbalanced mineral intake. Hair analysis reflects long-term mineral status. To determine the mineral content of hair from dogs... Read More about Mineral status in canine medial coronoid process disease: a cohort study using analysis of hair by mass spectrometry.

The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis (2017)
Journal Article
Morandi, E., Tanasescu, R., Tarlinton, R. E., Constantinescu, C. S., Zhang, W., Tench, C. R., & Gran, B. (2017). The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis. PLoS ONE, 12(2), Article e0172415. https://doi.org/10.1371/journal.pone.0172415

Background: The interaction between genetic and environmental factors is crucial to multiple sclerosis (MS) pathogenesis. Human Endogenous Retroviruses (HERVs) are endogenous viral elements of the human genome whose expression is associated with MS.... Read More about The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis.