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Association of season and herd size with somatic cell count for cows in Irish,English, and Welsh dairy herds (2013)
Journal Article
Archer, S. C., Mc Coy, F., Wapenaar, W., & Green, M. J. (2013). Association of season and herd size with somatic cell count for cows in Irish,English, and Welsh dairy herds. Veterinary Journal, 196(3), https://doi.org/10.1016/j.tvjl.2012.12.004

The aims of this study were to describe associations of time of year, and herd size with cow somatic cell count (SCC) for Irish, English, and Welsh dairy herds. Random samples of 497 and 493 Irish herds, and two samples of 200 English and Welsh (UK)... Read More about Association of season and herd size with somatic cell count for cows in Irish,English, and Welsh dairy herds.

Reliability and identification of aortic valve prolapse in the horse (2013)
Journal Article
Hallowell, G. D., & Bowen, M. (2013). Reliability and identification of aortic valve prolapse in the horse. BMC Veterinary Research, 9, Article 9. https://doi.org/10.1186/1746-6148-9-9

Background The objectives were to determine and assess the reliability of criteria for identification of aortic valve prolapse (AVP) using echocardiography in the horse. Results Opinion of equine cardiologists indicated that a long-axis view of... Read More about Reliability and identification of aortic valve prolapse in the horse.

Maternal undernutrition does not alter Sertoli cell numbers or the expression of key developmental markers in the mid-gestation ovine fetal testis (2013)
Journal Article
Andrade, L. P., Rhind, S. M., Rae, M. T., Kyle, C. E., Jowett, J., & Lea, R. G. (2013). Maternal undernutrition does not alter Sertoli cell numbers or the expression of key developmental markers in the mid-gestation ovine fetal testis. Journal of Negative Results in BioMedicine, 12(2), https://doi.org/10.1186/1477-5751-12-2

Background The aim of this study was to determine the effects of maternal undernutrition on ovine fetal testis morphology and expression of relevant histological indicators. Maternal undernutrition, in sheep, has been reported, previously, to alte... Read More about Maternal undernutrition does not alter Sertoli cell numbers or the expression of key developmental markers in the mid-gestation ovine fetal testis.

Epigenome-wide profiling identifies significant differences in DNA methylation between matched-pairs of T- and B-lymphocytes from healthy individuals (2013)
Journal Article
Glossop, J. R., Nixon, N. B., Emes, R. D., Haworth, K. E., Packham, J. C., Dawes, P. T., …Farrell, W. E. (2013). Epigenome-wide profiling identifies significant differences in DNA methylation between matched-pairs of T- and B-lymphocytes from healthy individuals. Epigenetics, 8(11), https://doi.org/10.4161/epi.26265

Multiple reports now describe changes to the DNA methylome in rheumatoid arthritis and in many cases have analyzed methylation in mixed cell populations from whole blood. However, these approaches may preclude the identification of cell type-specific... Read More about Epigenome-wide profiling identifies significant differences in DNA methylation between matched-pairs of T- and B-lymphocytes from healthy individuals.

Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy (2013)
Journal Article
Rauch, C., Ibrahim, H., & Foster, N. (2013). Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy. Journal of cancer therapeutics & research, 2, Article 20. https://doi.org/10.7243/2049-7962-2-20

Despite great medical advancement in the treatment of cancer, cancer remains a disease of global significance. Chemotherapeutics can be very expensive and drain medical resources at a national level and in some cases the cost of treatment is so great... Read More about Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy.

Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning (2013)
Journal Article
Swan, A. L., Hillier, K. L., Smith, J. R., Allaway, D., Liddell, S., Bacardit, J., & Mobasheri, A. (2013). Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning. BMC Musculoskeletal Disorders, 14, Article 349. https://doi.org/10.1186/1471-2474-14-349

Background: Osteoarthritis (OA) is an inflammatory disease of synovial joints involving the loss and degeneration of articular cartilage. The gold standard for evaluating cartilage loss in OA is the measurement of joint space width on standard radiog... Read More about Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning.

Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator (2012)
Journal Article
Mobasheri, A. (2012). Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator. Frontiers in Endocrinology, 3(153), Article 153. https://doi.org/10.3389/fendo.2012.00153

In the skeletal system glucose serves as an essential source of energy for the development, growth, and maintenance of bone and articular cartilage. It is particularly needed for skeletal morphogenesis during embryonic growth and fetal development. G... Read More about Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator.

Intersection of inflammation and herbal medicine in the treatment of osteoarthritis (2012)
Journal Article
Mobasheri, A. (2012). Intersection of inflammation and herbal medicine in the treatment of osteoarthritis. Current Rheumatology Reports, 14(6), https://doi.org/10.1007/s11926-012-0288-9

Herbal remedies and dietary supplements have become an important area of research and clinical practice in orthopaedics and rheumatology. Understanding the risks and benefits of using herbal medicines in the treatment of arthritis, rheumatic diseases... Read More about Intersection of inflammation and herbal medicine in the treatment of osteoarthritis.

Dairy herd health (2012)
Book
Green, M., Bradley, A., Breen, J., Green, L., Hayton, A., Higgins, H., …Statham, J. (Eds.). (2012). Dairy herd health. CABI

Dairy herd health is an important and universal topic in large animal veterinary practice and farming, covering both preventive medicine and health promotion. With the move towards large-scale farming, the health of the herd is important as an econom... Read More about Dairy herd health.

Managing herd reproduction (2012)
Book Chapter
Hudson, C., Kerby, M., Statham, J., & Wapenaar, W. (2012). Managing herd reproduction. In Dairy herd health (73-116). CAB International Publishing

Keeping an open mind: highlights and controversies of the breast cancer stem cell theory (2012)
Journal Article
Shah, M., & Allegrucci, C. (2012). Keeping an open mind: highlights and controversies of the breast cancer stem cell theory. Breast Cancer: Targets and Therapy, 2012(4), https://doi.org/10.2147/BCTT.S26434

The discovery that breast cancers contain stem-like cells has fuelled exciting research in the last few years. These cells are referred to as breast cancer stem cells (BCSCs) and are thought to be involved in tumor initiation, progression, and metast... Read More about Keeping an open mind: highlights and controversies of the breast cancer stem cell theory.

The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article
Tarlinton, R., Daly, J. M., Dunham, S. P., & Kydd, J. M. (2012). The challenge of Schmallenberg virus emergence in Europe. Veterinary Journal, 194(1), 10-18. https://doi.org/10.1016/j.tvjl.2012.08.017

The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in technology and collaboration between veterinary... Read More about The challenge of Schmallenberg virus emergence in Europe.

Reliability of quantitative echocardiography in adult sheep and goats (2012)
Journal Article
Hallowell, G. D., Potter, T. J., & Bowen, I. M. (2012). Reliability of quantitative echocardiography in adult sheep and goats. BMC Veterinary Research, 8(Septem), Article 11. https://doi.org/10.1186/1746-6148-8-181

Background Echocardiography is a non-invasive method for assessment of the ovine and caprine heart. Complete reference ranges for cardiac dimensions and time indices for both species are not currently available and reliability of these measurements... Read More about Reliability of quantitative echocardiography in adult sheep and goats.

Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female (2012)
Journal Article
Dottorini, T., Persampieri, T., Palladino, P., Baker, D. A., Spaccapelo, R., Senin, N., & Crisanti, A. (2013). Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female. FASEB Journal, 27(1), 86-97. doi:10.1096/fj.12-219444

In Drosophila, the accessory gland proteins (Acps) secreted from the male accessory glands (MAGs) and transferred along with sperm into the female reproductive tract have been implicated in triggering postmating behavioral changes, including refracto... Read More about Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female.

A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design (2012)
Journal Article
Higgins, H., Dryden, I. L., & Green, M. J. (2012). A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design. Preventive Veterinary Medicine, 106(2), https://doi.org/10.1016/j.prevetmed.2012.01.017

The two key aims of this research were: (i) to conduct a probabilistic elicitation to quantify the variation in veterinarians’ beliefs regarding the efficacy of systemic antibiotics when used as an adjunct to intra-mammary dry cow therapy and (ii) to... Read More about A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design.