All Outputs (9)

Fluctuations in auxin levels depend upon synchronicity of cell divisions in a one-dimensional model of auxin transport (2023)
Journal Article
Bellows, S., Janes, G., Avitabile, D., King, J. R., Bishopp, A., & Farcot, E. (2023). Fluctuations in auxin levels depend upon synchronicity of cell divisions in a one-dimensional model of auxin transport. PLoS Computational Biology, 19(11), Article e1011646. https://doi.org/10.1371/journal.pcbi.1011646

Auxin is a well-studied plant hormone, the spatial distribution of which remains incompletely understood. Here, we investigate the effects of cell growth and divisions on the dynamics of auxin patterning, using a combination of mathematical modelling... Read More about Fluctuations in auxin levels depend upon synchronicity of cell divisions in a one-dimensional model of auxin transport.

Root hydrotropism is controlled via a cortex-specific growth mechanism (2017)
Journal Article
Dietrich, D., Pang, L., Kobayashi, A., Fozard, J. A., Boudolf, V., Bhosale, R., …Bennett, M. J. (2017). Root hydrotropism is controlled via a cortex-specific growth mechanism. Nature Plants, 3(6), Article 17057. https://doi.org/10.1038/nplants.2017.57

Plants can acclimate by using tropisms to link the direction of growth to environmental conditions. Hydrotropism allows roots to forage for water, a process known to depend on abscisic acid (ABA) but whose molecular and cellular basis remains unclear... Read More about Root hydrotropism is controlled via a cortex-specific growth mechanism.

Hybrid vertex-midline modelling of elongated plant organs (2016)
Journal Article
Fozard, J. A., Bennett, M. J., King, J. R., & Jensen, O. E. (2016). Hybrid vertex-midline modelling of elongated plant organs. Interface Focus, 6(5), Article 20160043. https://doi.org/10.1098/rsfs.2016.0043

We describe a method for the simulation of the growth of elongated plant organs, such as seedling roots. By combining a midline representation of the organ on a tissue scale and a vertex-based representation on the cell scale, we obtain a multiscale... Read More about Hybrid vertex-midline modelling of elongated plant organs.

Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis (2016)
Journal Article
Mellor, N. L., Band, L. R., Pěnčík, A., Novak, O., Rashed, A., Holman, T., …Owen, M. R. (2016). Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis. Proceedings of the National Academy of Sciences, 113(39), 11022-11027. https://doi.org/10.1073/pnas.1604458113

Auxin is a key hormone regulating plant growth and development. We combine experiments and mathematical modeling to reveal how auxin levels are maintained via feedback regulation of genes encoding key metabolic enzymes. We describe how regulation of... Read More about Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis.

FlowerNet: a gene expression correlation metwork for anther and pollen development (2015)
Journal Article
Pearce, S., Ferguson, A., King, J., & Wilson, Z. A. (2015). FlowerNet: a gene expression correlation metwork for anther and pollen development. Plant Physiology, 167(4), https://doi.org/10.1104/pp.114.253807

Floral formation, in particular anther and pollen development, is a complex biological process with critical importance for seed set and for targeted plant breeding. Many key transcription factors regulating this process have been identified; however... Read More about FlowerNet: a gene expression correlation metwork for anther and pollen development.

Enhanced waterlogging tolerance in barley by manipulation of expression of the N-end rule pathway E3 ligase PROTEOLYSIS6 (2015)
Journal Article
Mendiondo, G. M., Gibbs, D. J., Szurman-Zubrzycka, M., Korn, A., Marquez, J., Szarejko, I., …Holdsworth, M. J. (2016). Enhanced waterlogging tolerance in barley by manipulation of expression of the N-end rule pathway E3 ligase PROTEOLYSIS6. Plant Biotechnology Journal, 14(1), 40-50. https://doi.org/10.1111/pbi.12334

© 2016 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd. Increased tolerance of crops to low oxygen (hypoxia) during flooding is a key target for food security. In Arabidopsis thaliana (L.) Heynh., the N... Read More about Enhanced waterlogging tolerance in barley by manipulation of expression of the N-end rule pathway E3 ligase PROTEOLYSIS6.

Promotion of testa rupture during garden cress germination involves seed compartment-specific expression and activity of pectin methylesterases (2015)
Journal Article
Scheler, C., Weitbrecht, K., Pearce, S. P., Hampstead, A., Büttner-Mainik, A., Lee, K. J., …Leubner-Metzger, G. (2015). Promotion of testa rupture during garden cress germination involves seed compartment-specific expression and activity of pectin methylesterases. Plant Physiology, 167(1),

Pectin methylesterase (PME) controls the methylesterification status of pectins and thereby determines the biophysical properties of plant cell walls, which are important for tissue growth and weakening processes. We demonstrate here that tissue-spec... Read More about Promotion of testa rupture during garden cress germination involves seed compartment-specific expression and activity of pectin methylesterases.

Systems Analysis of Auxin Transport in the Arabidopsis Root Apex (2014)
Journal Article
Band, L. R., Wells, D. M., Fozard, J. A., Ghetiu, T., French, A. P., Pound, M. P., …Bennett, M. J. (2014). Systems Analysis of Auxin Transport in the Arabidopsis Root Apex. Plant Cell, 26(3), 862-875. https://doi.org/10.1105/tpc.113.119495

Auxin is a key regulator of plant growth and development. Within the root tip, auxin distribution plays a crucial role specifying developmental zones and coordinating tropic responses. Determining how the organ-scale auxin pattern is regulated at the... Read More about Systems Analysis of Auxin Transport in the Arabidopsis Root Apex.

Stochastic and deterministic multiscale models for systems biology: An auxin-transport case study (2010)
Journal Article
Twycross, J., Band, L. R., Bennett, M. J., King, J. R., & Krasnogor, N. (2010). Stochastic and deterministic multiscale models for systems biology: An auxin-transport case study. BMC Systems Biology, 4, https://doi.org/10.1186/1752-0509-4-34

Background: Stochastic and asymptotic methods are powerful tools in developing multiscale systems biology models; however, little has been done in this context to compare the efficacy of these methods. The majority of current systems biology modellin... Read More about Stochastic and deterministic multiscale models for systems biology: An auxin-transport case study.