All Outputs (3)

Constitutive regulation of the Insl3 gene in rat Leydig cells (2005)
Journal Article
Sadeghian, H., Anand-Ivell, R., Balvers, M., Relan, V., & Ivell, R. (2005). Constitutive regulation of the Insl3 gene in rat Leydig cells. Molecular and Cellular Endocrinology, 241(1-2), 10-20. https://doi.org/10.1016/j.mce.2005.03.017

Insulin-like factor 3 (Insl3) is a major new product of the Leydig cells in all mammalian species so far examined. The rat Insl3 gene is encoded by two exons in close juxtaposition to the Jak3 gene. Using RT-PCR analysis we now show that in the rat t... Read More about Constitutive regulation of the Insl3 gene in rat Leydig cells.

Insulin-like factor 3: Where are we now? (2005)
Journal Article
Ivell, R., Hartung, S., & Anand-Ivell, R. (2005). Insulin-like factor 3: Where are we now?. Annals of the New York Academy of Sciences, 1041(1), 486-496. https://doi.org/10.1196/annals.1282.073

Insulin-like factor 3 (INSL3), previously known as the relaxin-like factor (RLF), is a major peptide hormone secreted from the testicular Leydig cells of adult men and circulating in the blood at a concentration of approximately 1 ng/mL. Women also p... Read More about Insulin-like factor 3: Where are we now?.

Relaxin Signaling from Natural Receptors (2005)
Journal Article
Ivell, R., Anand-Ivell, R., & Bartsch, O. (2005). Relaxin Signaling from Natural Receptors. Annals of the New York Academy of Sciences, 1041(1), 280-287. https://doi.org/10.1196/annals.1282.041

The heterodimeric peptide hormone relaxin in most cells appears to signal through a G-protein-coupled receptor, LGR7. Whereas in artificial cell systems, made by transfection of receptor-expressing gene constructs into cells normally not presenting t... Read More about Relaxin Signaling from Natural Receptors.