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Space farming: Horticulture systems on spacecraft and outlook to planetary space exploration (2022)
Journal Article
Nguyen, M. T. P., Knowling, M., Tran, N. N., Burgess, A., Fisk, I., Watt, M., …Hessel, V. (2023). Space farming: Horticulture systems on spacecraft and outlook to planetary space exploration. Plant Physiology and Biochemistry, 194, 708-721. https://doi.org/10.1016/j.plaphy.2022.12.017

Successful human space exploration requires more products than can be taken as payload. There is a need, therefore, for in-space circular manufacturing. Requirements for this include limited resource inflow, from either Earth or other planets and the... Read More about Space farming: Horticulture systems on spacecraft and outlook to planetary space exploration.

A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation (2022)
Journal Article
Huggett, Z. J., Smith, A., De Vivo, N., Gomez, D., Jethwa, P., Brameld, J. M., …Salter, A. M. (2022). A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation. Nutrients, 15(1), Article 40. https://doi.org/10.3390/nu15010040

Non-alcoholic fatty liver disease (NAFLD) begins with lipid accumulation within hepatocytes, but the relative contributions of different macronutrients is still unclear. We investigated the impact of fatty acids, glucose and fructose on lipid accumul... Read More about A Comparison of Primary Human Hepatocytes and Hepatoma Cell Lines to Model the Effects of Fatty Acids, Fructose and Glucose on Liver Cell Lipid Accumulation.

Impact of charged ionic species (NaCl and KCl) on the generation of color and volatile aroma compounds during caramelization (2022)
Journal Article
XU, S., LIU, Y., MU, X., CHEN, H., TAO, G., SUN, Z., …FISK, I. D. (2023). Impact of charged ionic species (NaCl and KCl) on the generation of color and volatile aroma compounds during caramelization. Food Science and Technology International, 43, Article e97622. https://doi.org/10.1590/fst.97622

During the process of caramelization, volatile and non-volatile flavor and color are generated via the degradation of carbohydrates. This research investigated the effect of the types and concentrations of salts including NaCl and KCl on the generati... Read More about Impact of charged ionic species (NaCl and KCl) on the generation of color and volatile aroma compounds during caramelization.

The Impact of the COVID-19 Pandemic on the Food Security of UK Adults Aged 20–65 Years (COVID-19 Food Security and Dietary Assessment Study) (2022)
Journal Article
Thomas, M., Eveleigh, E., Vural, Z., Rose, P., Avery, A., Coneyworth, L., & Welham, S. (2022). The Impact of the COVID-19 Pandemic on the Food Security of UK Adults Aged 20–65 Years (COVID-19 Food Security and Dietary Assessment Study). Nutrients, 14(23), Article 5078. https://doi.org/10.3390/nu14235078

The first UK lockdown greatly impacted the food security status of UK adults. This study set out to establish if food procurement was adapted differently for different income groups and if this impacted dietary intakes disproportionately. Adults (n=5... Read More about The Impact of the COVID-19 Pandemic on the Food Security of UK Adults Aged 20–65 Years (COVID-19 Food Security and Dietary Assessment Study).

Insulin-like peptide 3 (INSL3) in congenital hypogonadotrophic hypogonadism (CHH) in boys with delayed puberty and adult men (2022)
Journal Article
Abbara, A., Koysombat, K., Phylactou, M., Chia Eng, P., Clarke, S., Comninos, A. N., …Dhillo, W. S. (2022). Insulin-like peptide 3 (INSL3) in congenital hypogonadotrophic hypogonadism (CHH) in boys with delayed puberty and adult men. Frontiers in Endocrinology, 13, Article 1076984. https://doi.org/10.3389/fendo.2022.1076984

Background: Delayed puberty in males is almost invariably associated with constitutional delay of growth and puberty (CDGP) or congenital hypogonadotrophic hypogonadism (CHH). Establishing the cause at presentation is challenging, with “red flag” fea... Read More about Insulin-like peptide 3 (INSL3) in congenital hypogonadotrophic hypogonadism (CHH) in boys with delayed puberty and adult men.

Edible algae allergenicity – a short report (2022)
Journal Article
James, C. A., Welham, S., & Rose, P. (2023). Edible algae allergenicity – a short report. Journal of Applied Phycology, 35(1), 339–352. https://doi.org/10.1007/s10811-022-02880-2

The use of seaweed and algal derived products in the food industry has grown rapidly in recent times. Major areas of expansion have been in Western countries where algal derived commodities are being utilised as edible foods or sources of high value... Read More about Edible algae allergenicity – a short report.

The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease (2022)
Journal Article
Thapaliya, G., Eldeghaidy, S., Asghar, M., McGing, J., Radford, S., Francis, S., & Moran, G. W. (2022). The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease. Brain Imaging and Behavior, https://doi.org/10.1007/s11682-022-00742-6

Alterations in grey matter volume (GMV) and cortical thickness (CT) in Crohn’s disease (CD) patients has been previously documented. However, the findings are inconsistent, and not a true representation of CD burden, as only CD patients in remission... Read More about The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease.

The effects of exogenous fibrolytic enzymes on the in vitro release of xylooligosaccharides and monosaccharides varies across six varieties of wheat (2022)
Journal Article
Dale, T., Bedford, M. R., King, J., Tucker, G. A., Brameld, J. M., & Parr, T. (2023). The effects of exogenous fibrolytic enzymes on the in vitro release of xylooligosaccharides and monosaccharides varies across six varieties of wheat. Animal Feed Science and Technology, 295, Article 115526. https://doi.org/10.1016/j.anifeedsci.2022.115526

Wheat is a widely used cereal grain for pig and poultry feeds globally. Despite this, there are noticeable differences in its nutritive value, potentially due to varying characteristics like inherent non-starch polysaccharide (NSP) content and compos... Read More about The effects of exogenous fibrolytic enzymes on the in vitro release of xylooligosaccharides and monosaccharides varies across six varieties of wheat.

Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial (2022)
Journal Article
Bath, P. M., Skinner, C. J. C., Bath, C. S., Woodhouse, L. J., Areti, A., Korovesi, K., …Gordon, A. L. (2022). Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial. European Geriatric Medicine, 13, 1343-1355. https://doi.org/10.1007/s41999-022-00714-5

Purpose Infections cause considerable care home morbidity and mortality. Nitric oxide (NO) has broad-spectrum anti-viral, bacterial and yeast activity in vitro. We assessed the feasibility of supplementing dietary nitrate (NO substrate) intake in ca... Read More about Dietary nitrate supplementation for preventing and reducing the severity of winter infections, including COVID-19, in care homes (BEET-Winter)-a randomised placebo-controlled feasibility trial.

The effect of popping, soaking, boiling and roasting processes on antinutritional factors in chickpeas and red kidney beans (2022)
Journal Article
Godrich, J., Rose, P., Muleya, M., & Gould, J. (2023). The effect of popping, soaking, boiling and roasting processes on antinutritional factors in chickpeas and red kidney beans. International Journal of Food Science and Technology, 58(1), 279-289. https://doi.org/10.1111/ijfs.16190

This study was conducted to determine the effect that a popping head (like a rice cake machine), a low-shear and low-water processing technology, has on the concentration of antinutritional factors in chickpea and red kidney beans. Seeds were popped... Read More about The effect of popping, soaking, boiling and roasting processes on antinutritional factors in chickpeas and red kidney beans.

The Leydig cell biomarker INSL3 as a predictor of age-related morbidity: Findings from the EMAS cohort (2022)
Journal Article
Ivell, R., Heng, K., Severn, K., Antonio, L., Bartfai, G., Casanueva, F. F., …Anand-Ivell, R. (2022). The Leydig cell biomarker INSL3 as a predictor of age-related morbidity: Findings from the EMAS cohort. Frontiers in Endocrinology, 13, Article 1016107. https://doi.org/10.3389/fendo.2022.1016107

Background: Insulin-like peptide 3 (INSL3) is a constitutive hormone secreted in men by the mature Leydig cells of the testes. It is an accurate biomarker for Leydig cell functional capacity, reflecting their total cell number and differentiation sta... Read More about The Leydig cell biomarker INSL3 as a predictor of age-related morbidity: Findings from the EMAS cohort.

Using correlation matrices to standardise sweet liking status classification (2022)
Journal Article
Kavaliauskaite, G., Thibodeau, M., Ford, R., & Yang, Q. (2023). Using correlation matrices to standardise sweet liking status classification. Food Quality and Preference, 104, Article 104759. https://doi.org/10.1016/j.foodqual.2022.104759

Distinct hedonic patterns of sweet taste liking have been widely recognised for more than half a century. Despite there being a growing consensus on the role of Sweet Liking Status (SLS) in food choice behaviour, current classification methods for th... Read More about Using correlation matrices to standardise sweet liking status classification.

The Winged Bean Genome: Winged Bean—One Species Supermarket (2022)
Book Chapter
Tsoutsoura, N., Chong, Y. T., Ho, W. K., Chai, H. H., Tanzi, A. S., Salazar-Licea, L., …Mayes, S. (2022). The Winged Bean Genome: Winged Bean—One Species Supermarket. In M. A. Chapman (Ed.), Underutilised Crop Genomes (315-336). Springer International Publishing. https://doi.org/10.1007/978-3-031-00848-1_17

Climate change, population growth and increasingly homogenised diets are a threat to food security and human nutritional status. There is an urgent need to incorporate highly nutritious crops into the human diet to provide new sources of nutrition, t... Read More about The Winged Bean Genome: Winged Bean—One Species Supermarket.

The role of inorganic-phosphate, potassium and magnesium in yeast-flavour formation (2022)
Journal Article
Ribeiro-Filho, N., Linforth, R., Bora, N., Powell, C. D., & Fisk, I. D. (2022). The role of inorganic-phosphate, potassium and magnesium in yeast-flavour formation. Food Research International, 162, Article 112044. https://doi.org/10.1016/j.foodres.2022.112044

Inorganic-phosphate, potassium, and magnesium are key-minerals required for yeast growth, metabolism, and survival, the present work investigated its impact in yeast-flavour formation using a multi-factor experimental design, which was used to genera... Read More about The role of inorganic-phosphate, potassium and magnesium in yeast-flavour formation.

Natural products in drug discovery and development: Synthesis and medicinal perspective of leonurine (2022)
Journal Article
Li, Z., Chen, K., Rose, P., & Zhu, Y. Z. (2022). Natural products in drug discovery and development: Synthesis and medicinal perspective of leonurine. Frontiers in Chemistry, 10, Article 1036329. https://doi.org/10.3389/fchem.2022.1036329

Natural products, those molecules derived from nature, have been used by humans for thousands of years to treat ailments and diseases. More recently, these compounds have inspired chemists to use natural products as structural templates in the develo... Read More about Natural products in drug discovery and development: Synthesis and medicinal perspective of leonurine.

Effect of popping water content and amylose/amylopectin ratio on the physical properties of expanded starch products with different shear histories (2022)
Journal Article
Beech, D., Beech, J., Gould, J., & Hill, S. (2022). Effect of popping water content and amylose/amylopectin ratio on the physical properties of expanded starch products with different shear histories. International Journal of Food Science and Technology, 57(11), 7368-7378. https://doi.org/10.1111/ijfs.16092

Aerated starch products are a staple of the food industry, with particular relevance in the snack market. Water plays a crucial role in the formation of such products due to its utility both as a blowing agent and as a starch plasticiser. Amylose/amy... Read More about Effect of popping water content and amylose/amylopectin ratio on the physical properties of expanded starch products with different shear histories.

Influence of income on diet quality and daily iron and zinc intake: Analysis of the National Diet and Nutrition Survey of British females aged 11-14 and 15-18 years (2022)
Journal Article
Thomas, M., Coneyworth, L., & Welham, S. (2023). Influence of income on diet quality and daily iron and zinc intake: Analysis of the National Diet and Nutrition Survey of British females aged 11-14 and 15-18 years. European Journal of Nutrition, 62(1), 499–510. https://doi.org/10.1007/s00394-022-03000-z

Purpose: A negative socio-economic gradient exists for diet and health outcomes. Since cheaper diets are associated with increased energy and lower nutrient density, we investigated the influence of income on iron and zinc intakes and overall diet qu... Read More about Influence of income on diet quality and daily iron and zinc intake: Analysis of the National Diet and Nutrition Survey of British females aged 11-14 and 15-18 years.

Diet and irritable bowel syndrome: an update from a UK consensus meeting (2022)
Journal Article
Rej, A., Avery, A., Aziz, I., Black, C. J., Bowyer, R. K., Buckle, R. L., …Sanders, D. S. (2022). Diet and irritable bowel syndrome: an update from a UK consensus meeting. BMC Medicine, 20(1), Article 287. https://doi.org/10.1186/s12916-022-02496-w

There has been a renewed interest in the role of dietary therapies to manage irritable bowel syndrome (IBS), with diet high on the agenda for patients. Currently, interest has focussed on the use of traditional dietary advice (TDA), a gluten-free die... Read More about Diet and irritable bowel syndrome: an update from a UK consensus meeting.

The Response of the Human Umbilical Vein Endothelial Cell Transcriptome to Variation in Magnesium Concentration (2022)
Journal Article
Almousa, L. A., Salter, A. M., Castellanos, M., May, S. T., & Langley-Evans, S. C. (2022). The Response of the Human Umbilical Vein Endothelial Cell Transcriptome to Variation in Magnesium Concentration. Nutrients, 14(17), Article 3586. https://doi.org/10.3390/nu14173586

Vascular endothelial cells have a critical role in the maintenance of cardiovascular function. Evidence suggests that endothelial function may be compromised under conditions of magnesium deficiency, which increases vulnerability to inflammation. Who... Read More about The Response of the Human Umbilical Vein Endothelial Cell Transcriptome to Variation in Magnesium Concentration.