All Outputs (202)
Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model (2013)
Journal Article
Steroidogenic tissues such as the ovary, testes or adrenal glands are paradoxical in that they often indicate actions of steroid hormones within a dynamic range of ligand concentration in a high nanomolar or even micromolar level, i.e. at the natural... Read More about Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model.
INSL3 as a biomarker of Leydig cell functionality (2013)
Journal Article
Insulin-like factor 3 (INSL3) is a small peptide hormone made and secreted uniquely by mature Leydig cells in the testes of all mammals. Importantly, this expression and secretion appears to be constitutive and therefore reflects the differentiation... Read More about INSL3 as a biomarker of Leydig cell functionality.
Insulin-like peptide 3 (INSL3), a major product of testicular Leydig cells, is also expressed by the ovary, but its functional role remains poorly understood. Here, we quantified expression of INSL3 and its receptor RXFP2 in theca interna cell (TIC)... Read More about Ovarian expression of Insulin-Like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles.
Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production (2013)
Journal Article
Bone morphogenetic proteins (BMPs) are firmly implicated as intraovarian regulators of follicle development and steroidogenesis. Here we report a microarray analysis showing that treatment of cultured bovine theca cells (TC) with BMP6 significantly (... Read More about Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
Neohormones as biomarkers of reproductive health (2013)
Journal Article
Neohormone systems are defined as evolutionarily new endocrine or paracrine adaptations that supplement basic physiologic functions and define mammalian success. The relaxin family of peptide hormones are typical neohormones. Because they define the... Read More about Neohormones as biomarkers of reproductive health.
Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring (2013)
Journal Article
Maternal exposure to estrogenic xenobiotics or phthalates has been implicated in the distortion of early male reproductive development, referred to in humans as the testicular dysgenesis syndrome. It is not known, however, whether such early gestatio... Read More about Brief maternal exposure of rats to the xenobiotics dibutyl phthalate or diethylstilbestrol alters adult-type Leydig cell development in male offspring.
Basolateral amygdala activity during the retrieval of associative learning under anesthesia (2013)
Journal Article
Associative learning can occur under anesthesia and its neural correlates have begun to be elucidated. During discrimination learning under anesthesia in rats, lateral amygdala excitability increases in response to a conditioned stimulus (CS+) previo... Read More about Basolateral amygdala activity during the retrieval of associative learning under anesthesia.
On-farm methane measurements during milking correlate with total methane production by individual dairy cows (2012)
Journal Article
The objective of this study was to investigate whether measurement of methane emissions by individual dairy cows during milking could provide a useful technique for monitoring on-farm methane emissions. To quantify methane emissions from individual c... Read More about On-farm methane measurements during milking correlate with total methane production by individual dairy cows.
Variation among individual dairy cows in methane measurements made on farm during milking (2012)
Journal Article
The objective of this study was to quantify on-farm variation between and within cows in methane emissions measured during milking, and to determine which factors are related to this variation. Methane emission rate during milking (MERm) was recorded... Read More about Variation among individual dairy cows in methane measurements made on farm during milking.
Mechanical properties of the bovine claw horn during lactation (2012)
Journal Article
Claw horn disorders are one of the main causes of lameness in dairy cows globally. This study aimed to develop material testing techniques to assess changes in the mechanical properties of bovine claw horn (BCH) and to compare these mechanical proper... Read More about Mechanical properties of the bovine claw horn during lactation.
Biosecurity on cattle farms: a study in North-West England (2012)
Journal Article
Background: Few studies have considered in detail the range of biosecurity practices undertaken on cattle farms, particularly within the UK. In this study, 56 cattle farmers in a 100 km2 area of north-west England were questioned regarding their on-f... Read More about Biosecurity on cattle farms: a study in North-West England.
Role of amygdala-prefrontal cortex circuitry in regulating the expression of contextual fear memory (2011)
Journal Article
The basolateral amygdala (BLA) and medial prefrontal cortex (mPFC) are inter-connected regions involved in fear memory expression. The reciprocal nature of projections between these areas differs along the rostrocaudal extent of BLA. This study inves... Read More about Role of amygdala-prefrontal cortex circuitry in regulating the expression of contextual fear memory.
Early life programming of fear conditioning and extinction in adult male rats (2009)
Journal Article
The early rearing environment programs corticolimbic function and neuroendocrine stress reactivity in adulthood. Although early environmental programming of innate fear has been previously examined, its impact on fear learning and memory later in lif... Read More about Early life programming of fear conditioning and extinction in adult male rats.
Neonatal maternal separation alters reward-related ultrasonic vocalizations in rat dams (2009)
Journal Article
We examined the effects of brief or long durations of repeated maternal separation (MS) on ultrasonic vocalizations (USVs) in rat dams. 50-kHz USVs putatively identified as maternal in origin were emitted only immediately after pups were returned fol... Read More about Neonatal maternal separation alters reward-related ultrasonic vocalizations in rat dams.
Early life programming of innate fear and fear learning in adult female rats (2008)
Journal Article
The early rearing environment can impact on emotional reactivity and learning later in life. In this study the effects of neonatal maternal separation (MS) on innate fear and fear learning were assessed in the adult female rat. Pups were subjected to... Read More about Early life programming of innate fear and fear learning in adult female rats.
Early life programming of hemispheric lateralization and synchronization in the adult medial prefrontal cortex (2008)
Journal Article
Neonatal maternal separation (MS) in the rat increases the vulnerability to stressors later in life. In contrast, brief handling (H) in early life confers resilience to stressors in adulthood. Early life programming of stress reactivity may involve t... Read More about Early life programming of hemispheric lateralization and synchronization in the adult medial prefrontal cortex.
Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos (2008)
Journal Article
The oocyte is remarkable in its ability to remodel parental genomes following fertilization and to reprogram somatic nuclei after nuclear transfer (NT). To characterize the patterns of histone H4 acetylation and DNA methylation during development of... Read More about Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos.
Early life stress causes FG-7142-induced corticolimbic dysfunction in adulthood (2007)
Journal Article
Maternal separation (MS) during the neonatal period enhances stress responsivity in adulthood. The medial prefrontal cortex (mPFC) and the basolateral amygdala (BLA) are involved in coordinating various stress responses. Evidence indicates that MS re... Read More about Early life stress causes FG-7142-induced corticolimbic dysfunction in adulthood.
Systemic administration of the benzodiazepine receptor partial inverse agonist FG-7142 disrupts corticolimbic network interactions (2007)
Journal Article
The medial prefrontal cortex (mPFC) and basolateral amygdala(BLA) coordinate various stress responses. Although the effects of stressors on mPFCand BLA activity have been previously examined, it remains unclear to what extent stressors affect functio... Read More about Systemic administration of the benzodiazepine receptor partial inverse agonist FG-7142 disrupts corticolimbic network interactions.