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All Outputs (54)

Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils (2015)
Journal Article

Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding... Read More about Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils.

Modelling maternal obesity: the effects of a chronic high-fat, high-cholesterol diet on uterine expression of contractile-associated proteins and ex vivo contractile activity during labour in the rat (2015)
Journal Article

Maternal obesity is associated with prolonged and dysfunctional labour and emergency caesarean section, but the mechanisms are unknown. The present study investigated the effects of an adiposity-inducing high fat, high-cholesterol (HFHC) diet on uter... Read More about Modelling maternal obesity: the effects of a chronic high-fat, high-cholesterol diet on uterine expression of contractile-associated proteins and ex vivo contractile activity during labour in the rat.

Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring (2015)
Journal Article

© Copyright 2015 The Authors. The Western diet is typically high in salt and fructose, which have pressor activity. Maternal diet can affect offspring blood pressure, but the extent to which maternal intake of excess salt and fructose may influence c... Read More about Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring.

Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation (2015)
Journal Article

Pigs are evidently more resistant to avian than swine influenza A viruses, mediated in part through frontline epithelial cells and alveolar macrophages (AM). Although porcine AM (PAM) are crucial in influenza virus control, their mode of control is u... Read More about Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation.

Long-term reindeer grazing limits warming-induced increases in CO2 released by tundra heath soil: potential role of soil C quality (2015)
Journal Article

© 2015 IOP Publishing Ltd. The current climate warming in the Arctic may increase the microbial degradation of vast pools of soil carbon (C); however, the temperature sensitivity of decomposition is often highly dependent on the quality of accumulate... Read More about Long-term reindeer grazing limits warming-induced increases in CO2 released by tundra heath soil: potential role of soil C quality.

Impact of neonicotinoid seed treatment of cotton on the cotton leafhopper, Amrasca devastans(Hemiptera: Cicadellidae), and its natural enemies (2015)
Journal Article

BACKGROUND Neonicotinoid seed treatments suppress populations of pest insects efficiently and can enhance crop growth, but they may have negative effects on beneficial arthropods. We evaluated the effects of either imidacloprid or thiamethoxam on th... Read More about Impact of neonicotinoid seed treatment of cotton on the cotton leafhopper, Amrasca devastans(Hemiptera: Cicadellidae), and its natural enemies.

The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana (2015)
Journal Article

Background: Plant cell walls are dynamic structures involved in all aspects of plant growth, environmental interactions and defense responses, and are the most abundant renewable source of carbon-containing polymers on the planet. To balance rigidity... Read More about The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana.

Impact of altered cell wall composition on saccharification efficiency in stem tissue of Arabidopsis RABA GTPase-deficient knockout mutants (2015)
Journal Article

Use of biomass for second-generation biofuel production is severely hindered by the inherent recalcitrance of the plant cell wall to digestion. Trafficking is crucial for compartmentalisation within the cell. This process is partly regulated by small... Read More about Impact of altered cell wall composition on saccharification efficiency in stem tissue of Arabidopsis RABA GTPase-deficient knockout mutants.