Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin
(2017)
Journal Article
Phillips-Jones, M. K., Channell, G. A., Kelsall, C. J., Hughes, C. S., Ashcroft, A. E., Patching, S. G., …Harding, S. E. (2017). Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin. Scientific Reports, 7(1), 1-12. https://doi.org/10.1038/srep46180
VanA-type resistance to glycopeptide antibiotics in clinical enterococci is regulated by the VanSARA two-component signal transduction system. The nature of the molecular ligand that is recognised by the VanSA sensory component has not hitherto been... Read More about Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin.