Computational assessment of drug-induced effects on the electrocardiogram: From ion channel to body surface potentials
(2013)
Journal Article
Zemzemi, N., Bernabeu, M. O., Saiz, J., Cooper, J., Pathmanathan, P., Mirams, G. R., …Rodriguez, B. (2013). Computational assessment of drug-induced effects on the electrocardiogram: From ion channel to body surface potentials. British Journal of Pharmacology, 168(3), 718-733. https://doi.org/10.1111/j.1476-5381.2012.02200.x
Background and Purpose: Understanding drug effects on the heart is key to safety pharmacology assessment and anti-arrhythmic therapy development. Here our goal is to demonstrate the ability of computational models to simulate the effect of drug actio... Read More about Computational assessment of drug-induced effects on the electrocardiogram: From ion channel to body surface potentials.