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Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study (2024)
Journal Article
Sahota, O., Narayanasamy, M., Bastounis, A., Paskins, Z., Bishop, S., Langley, T., …Leonardi-Bee, J. (2024). Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study. Health Technology Assessment, 28(21), https://doi.org/10.3310/WYPF0472

Background: Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosph... Read More about Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study.

Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study (2023)
Journal Article
Bishop, S., Narayanasamy, M. J., Paskins, Z., Corp, N., Bastounis, A., Griffin, J., …Sahota, O. (2023). Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study. BMC Musculoskeletal Disorders, 24, Article 770. https://doi.org/10.1186/s12891-023-06865-1

Background Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly tak... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.

Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults (2022)
Journal Article
Narayanasamy, M., Bishop, S., Sahota, O., Paskins, Z., Gittoes, N., & Langley, T. (2022). Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults. Age and Ageing, 51(11), Article afac255. https://doi.org/10.1093/ageing/afac255

Background: Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost. Improving long-term adherence with bisphosphonate treatments reduces fracture risk, but adherence rates for first line oral bi... Read More about Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults.

Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis. (2020)
Journal Article
Paskins, Z., Crawford-Manning, F., Cottrell, E., Corp, N., Wright, J., Jinks, C., …Sahota, O. (2020). Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis. BMJ Open, 10(11), Article e040634. https://doi.org/10.1136/bmjopen-2020-040634

OBJECTIVE: To explore the acceptability of different bisphosphonate regimens for the treatment of osteoporosis among patients, clinicians and managers, payers and academics. DESIGN: A systematic review of primary qualitative studies. Seven databas... Read More about Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis..