All Outputs (15)

Toll-Like Receptor Signalling Pathways Regulate Hypoxic Stress Induced Fibroblast Growth Factor but Not Vascular Endothelial Growth Factor-A in Human Microvascular Endothelial Cells (2021)
Journal Article

Retinal diseases are the leading causes of irreversible blindness worldwide. The role of toll-like receptor (TLR) signalling mechanisms (MyD88 and TRIF) in the production of pro-angiogenic growth factors from human microvascular endothelial cells (HM... Read More about Toll-Like Receptor Signalling Pathways Regulate Hypoxic Stress Induced Fibroblast Growth Factor but Not Vascular Endothelial Growth Factor-A in Human Microvascular Endothelial Cells.

Morbidity and Complications of Diabetes Mellitus in Children and Adolescents in Ghana: Protocol for a longitudinal study (2021)
Journal Article

Diabetic retinopathy and diabetic macular oedema pathways and management: UK Consensus Working Group (2020)
Journal Article

Comparison of the Morphology of the Foveal Pit Between African and Caucasian Populations (2020)
Journal Article

Purpose: The purpose of this study was to characterize foveal pit morphology in an African (Ghanaian) population, to compare it to that of a Caucasian group and to determine if it varied with age in the two populations. Methods: The depth, diamet... Read More about Comparison of the Morphology of the Foveal Pit Between African and Caucasian Populations.

The aetiology of Spaceflight‐Associated Neuro‐ocular Syndrome (SANS) might be explained by a neural mechanism regulating intraocular pressure (2020)
Journal Article

Hypercapnia augments resistive exercise?induced elevations in intraocular pressure in older individuals (2020)
Journal Article

The present study assessed the effect of 6° head down (establishing the cephalad displacement noted in astronauts in microgravity) prone (simulating the effect on the eye) tilt during rest and exercise (simulating exercise performed by astronauts to... Read More about Hypercapnia augments resistive exercise?induced elevations in intraocular pressure in older individuals.

Patient-reported reasons for delay in diagnosis of age-related macular degeneration: a national survey (2019)
Journal Article

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objectives To investigate whether people with age-related macular degeneration (AMD) are able to self-detect... Read More about Patient-reported reasons for delay in diagnosis of age-related macular degeneration: a national survey.

Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies (2019)
Journal Article

© 2019, The Author(s). Purpose: Fixation stability (FS) of the preferred retinal locus (PRL) may be improved by biofeedback fixation training (BFT) with microperimetry. Such training can be done on the patient’s PRL or in different retinal loci with... Read More about Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies.

In vivo confocal microscopy features and clinicohistological correlation of limbal nerve corpuscles (2019)
Journal Article

Aims To describe the in vivo confocal microscopy (IVCM) features of human limbal nerve corpuscles (LNCs) and correlate these with the histological features. Methods We examined 40 eyes of 29 healthy living subjects (17 female, 12 male; mean age=47... Read More about In vivo confocal microscopy features and clinicohistological correlation of limbal nerve corpuscles.

Assessing the ex vivo permeation behaviour of functionalised contact lens coatings engineered using an electrohydrodynamic technique (2018)
Journal Article

In vitro testing alone is no longer considered sufficient evidence presented solely with respect to drug release and permeation testing. These studies are thought to be more reliable and representative when using tissue or animal models; as opposed t... Read More about Assessing the ex vivo permeation behaviour of functionalised contact lens coatings engineered using an electrohydrodynamic technique.

Prevalence of peripapillary choroidal neovascular membranes (PPCNV) in an elderly UK population—the Bridlington eye assessment project (BEAP): a cross-sectional study (2002–2006) (2018)
Journal Article

© 2018, The Royal College of Ophthalmologists. Purpose: There is paucity of data on the epidemiology of peripapillary choroidal neovascularisartion (PPCNV). Our aim was to determine prevalence of PPCNV in the elderly UK population of Bridlington res... Read More about Prevalence of peripapillary choroidal neovascular membranes (PPCNV) in an elderly UK population—the Bridlington eye assessment project (BEAP): a cross-sectional study (2002–2006).

Epiretinal Membrane Surgery Outcomes in Eyes with Subretinal Drusenoid Deposits: A Case Control Study (2018)
Journal Article

© 2018 Purpose: To evaluate outcomes of epiretinal membrane (ERM) surgery in eyes with subretinal drusenoid deposits (SRDDs) and to compare them with those with isolated ERM. Design: Retrospective case-control study of consecutive patients who underw... Read More about Epiretinal Membrane Surgery Outcomes in Eyes with Subretinal Drusenoid Deposits: A Case Control Study.

Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPAR?) are disrupted by retinal disease-associated mutations (2017)
Journal Article

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the Nuclear Receptor (NR) superfamily of transcription factors. We assessed... Read More about Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPAR?) are disrupted by retinal disease-associated mutations.

Expression of Toll-like receptors in human retinal and choroidal vascular endothelial cells (2015)
Journal Article

The effect of hyperglycaemia on permeability and the expression of junctional complex molecules in human retinal and choroidal endothelial cells. (2014)
Journal Article

Diabetic retinopathy is the leading cause of preventable blindness in the working population and its prevalence continues to increase as the worldwide prevalence of diabetes grows. Diabetic choroidopathy is less well studied and occurs in the late st... Read More about The effect of hyperglycaemia on permeability and the expression of junctional complex molecules in human retinal and choroidal endothelial cells..