Remote Ischemic Conditioning After Stroke Trial 2: A Phase IIb Randomized Controlled Trial in Hyperacute Stroke
(2019)
Journal Article
England, T. J., Hedstrom, A., O'Sullivan, S. E., Woodhouse, L., Jackson, B., & Sprigg, N. (2019). Remote Ischemic Conditioning After Stroke Trial 2: A Phase IIb Randomized Controlled Trial in Hyperacute Stroke. Journal of the American Heart Association, 8(23), https://doi.org/10.1161/JAHA.119.013572
All Outputs (5)
Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage (2019)
Journal Article
Bath, P. M., Woodhouse, L. J., Krishnan, K., Appleton, J. P., Anderson, C. S., Berge, E., …Sprigg, N. (2019). Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage. Stroke, 50(11), 3064-3071. https://doi.org/10.1161/STROKEAHA.119.026389Background and Purpose— Pilot trials suggest that glyceryl trinitrate (GTN; nitroglycerin) may improve outcome when administered early after stroke onset. Methods— We undertook a multicentre, paramedic-delivered, ambulance-based, prospective ran... Read More about Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage.
Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT (2019)
Journal Article
Coates, E., Thomas, S. A., Drummond, A. E., Lincoln, N. B., Palmer, R. L., Sutherland, K. E., …Topcu, G. (2019). Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT. Health Technology Assessment, 23(47), 1-176. https://doi.org/10.3310/hta23470Background: There is currently insufficient evidence for the clinical effectiveness and cost-effectiveness of psychological therapies for post-stroke depression. Objective: To evaluate the feasibility of undertaking a definitive trial to evaluate the... Read More about Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT.
A systematic review of cannabidiol dosing in clinical populations (2019)
Journal Article
Millar, S. A., Stone, N., Bellman, Z., Yates, A., England, T., & O'Sullivan, S. (2019). A systematic review of cannabidiol dosing in clinical populations. British Journal of Clinical Pharmacology, 85(9), 1888-1900. https://doi.org/10.1111/bcp.14038Aims: Cannabidiol is a cannabis-derived medicinal product with potential application in a wide-variety of contexts, however its effective dose in different disease states remains unclear. This review aimed to investigate what doses have been applied... Read More about A systematic review of cannabidiol dosing in clinical populations.
A novel transwell blood brain barrier model using primary human cells (2019)
Journal Article
Stone, N. L., England, T. J., & O’Sullivan, S. E. (2019). A novel transwell blood brain barrier model using primary human cells. Frontiers in Cellular Neuroscience, 13, Article 230. https://doi.org/10.3389/fncel.2019.00230© 2019 Stone, England and O’Sullivan. Structural alterations and breakdown of the blood brain barrier (BBB) is often a primary or secondary consequence of disease, resulting in brain oedema and the transport of unwanted substances into the brain. It... Read More about A novel transwell blood brain barrier model using primary human cells.