Sophie A. Millar
A systematic review of cannabidiol dosing in clinical populations
Millar, Sophie A.; Stone, N.L.; Bellman, Z.D.; Yates, A.S.; England, T.J.; O'Sullivan, S.E.
Authors
N.L. Stone
Z.D. Bellman
A.S. Yates
TIMOTHY ENGLAND Timothy.England@nottingham.ac.uk
Professor of Stroke Medicine
S.E. O'Sullivan
Abstract
Aims: Cannabidiol is a cannabis-derived medicinal product with potential application in a wide-variety of contexts, however its effective dose in different disease states remains unclear. This review aimed to investigate what doses have been applied in clinical populations, in order to understand the active range of cannabidiol in a variety of medical contexts.
Methods: Publications involving administration of cannabidiol alone were collected by searching PubMed, EMBASE and ClinicalTrials.gov.
Results: A total of 1038 articles were retrieved, of which 35 studies met inclusion criteria covering 13 medical contexts. 23 studies reported a significant improvement in primary outcomes (e.g. psychotic symptoms, anxiety, seizures), with doses ranging between
Citation
Millar, S. A., Stone, N., Bellman, Z., Yates, A., England, T., & O'Sullivan, S. (2019). A systematic review of cannabidiol dosing in clinical populations. British Journal of Clinical Pharmacology, 85(9), 1888-1900. https://doi.org/10.1111/bcp.14038
Journal Article Type | Article |
---|---|
Acceptance Date | Jun 10, 2019 |
Online Publication Date | Jul 19, 2019 |
Publication Date | 2019-09 |
Deposit Date | Jun 20, 2019 |
Publicly Available Date | Mar 29, 2024 |
Journal | British Journal of Clinical Pharmacology |
Print ISSN | 0306-5251 |
Electronic ISSN | 1365-2125 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
Volume | 85 |
Issue | 9 |
Pages | 1888-1900 |
DOI | https://doi.org/10.1111/bcp.14038 |
Keywords | cannabidiol; cannabinoid; therapeutics; dose; dosing 11 |
Public URL | https://nottingham-repository.worktribe.com/output/2212209 |
Publisher URL | https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.14038 |
Files
bcp.14038
(1.5 Mb)
PDF
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
You might also like
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: digital-library-support@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search