The need to move away from fecal transplant towards targeted, refined microbiome therapy
(2018)
Journal Article
All Outputs (8)
The mechanisms of efficacy for fecal microbiota# transplantation (FMT) in treating recurrent Clostridioides difficile infection (rCDI) remain poorly defined, with restored gut microbiota-bile acid interactions representing one possible explanation. F... Read More about Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in bile acid-farnesoid X receptor-fibroblast growth factor pathway.
A protein microarray assay for serological determination of antigen-specific antibody responses following Clostridium difficile infection (2018)
Journal Article
We provide a detailed overview of a novel high-throughput protein microarray assay for the determination of anti-C. difficile antibody levels in human sera and in separate preparations of polyclonal IVIg. The protocol describes the methodological ste... Read More about A protein microarray assay for serological determination of antigen-specific antibody responses following Clostridium difficile infection.
High prevalence of Clostridium difficile Ribotype 078 in IBD outpatients (2018)
Journal Article
Novel oral targeted therapies in inflammatory bowel disease (2018)
Journal Article
Background: There is a great unmet clinical need for efficacious, tolerable, economical and orally administrated drugs for the treatment of inflammatory bowel disease (IBD). New therapeutic avenues have become possible including the development of me... Read More about Novel oral targeted therapies in inflammatory bowel disease.
Orbital inflammatory complications of Crohn’s disease: a rare case series (2018)
Journal Article
Orbital inflammatory disease is a rare ophthalmic manifestation of Crohn’s disease. Inflammation is characteristically non-specific, involving one or multiple structures of the orbit. Mechanisms of disease and optimal methods of treatment are poorly... Read More about Orbital inflammatory complications of Crohn’s disease: a rare case series.