Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

Wain, Louise V.; Shrine, Nick; Miller, Suzanne; Jackson, Victoria E.; Ntalla, Ioanna; Artigas, Mar�a Soler; Billington, Charlotte K.; Kheirallah, Abdul Kader; Allen, Richard; Cook, James P.; Probert, Kelly; Obeidat, Ma'en; Boss�, Yohan; Hao, Ke; Postma, Dirkje S.; Par�, Peter D.; Ramasamy, Adaikalavan; M�gi, Reedik; Mihailov, Evelin; Reinmaa, Eva; Mel�n, Erik; O'Connell, Jared; Frangou, Eleni; Delaneau, Olivier; Freeman, Colin; Petkova, Desislava; McCarthy, Mark; Sayers, Ian; Deloukas, Panos; Hubbard, Richard; Pavord, Ian; Hansell, Anna L.; Thomson, Neil C.; Zeggini, Eleftheria; Morris, Andrew P.; Marchini, Jonathan; Strachan, David P.; Tobin, Martin D.; Hall, Ian P.

doi:10.1016/S2213-2600(15)00283-0

Research Repository

All Outputs (2)

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (2015)
Journal Article

Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease. In 38,199 European ancestry individuals, we studied genome-wide association of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC... Read More about Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank (2015)
Journal Article

Background Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking behav... Read More about Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.