All Outputs (3)

Campylobacter bacteriophage DA10: An excised temperate bacteriophage targeted by CRISPR-cas (2020)
Journal Article
Hooton, S., D’Angelantonio, D., Hu, Y., Connerton, P. L., Aprea, G., & Connerton, I. F. (2020). Campylobacter bacteriophage DA10: An excised temperate bacteriophage targeted by CRISPR-cas. BMC Genomics, 21(1), Article 400. https://doi.org/10.1186/s12864-020-06808-3

Background: Lytic bacteriophages that infect Campylobacter spp. have been utilized to develop therapeutic/decontamination techniques. However, the association of Campylobacter spp. and bacteriophages has been the focus of several strands of research... Read More about Campylobacter bacteriophage DA10: An excised temperate bacteriophage targeted by CRISPR-cas.

A generalised model for generalised transduction: the importance of co-evolution and stochasticity in phage mediated antimicrobial resistance transfer (2020)
Journal Article
Arya, S., Todman, H., Baker, M., Hooton, S., Millard, A., Kreft, J. U., …Stekel, D. J. (2020). A generalised model for generalised transduction: the importance of co-evolution and stochasticity in phage mediated antimicrobial resistance transfer. FEMS Microbiology Ecology, 96(7), https://doi.org/10.1093/femsec/fiaa100

© FEMS 2020. Antimicrobial resistance is a major global challenge. Of particular concern are mobilizable elements that can transfer resistance genes between bacteria, leading to pathogens with new combinations of resistance. To date, mathematical mod... Read More about A generalised model for generalised transduction: the importance of co-evolution and stochasticity in phage mediated antimicrobial resistance transfer.

Bacteriophage ZCSE2 is a Potent Antimicrobial against Salmonella enterica Serovars: Ultrastructure, genomics and efficacy (2020)
Journal Article
Mohamed, A., Taha, O., El-Sherif, H. M., Connerton, P. L., Hooton, S. P., Bassim, N. D., …El-Shibiny, A. (2020). Bacteriophage ZCSE2 is a Potent Antimicrobial against Salmonella enterica Serovars: Ultrastructure, genomics and efficacy. Viruses, 12(4), 1-20. https://doi.org/10.3390/v12040424

© 2020 by the authors. Developing novel antimicrobials capable of controlling multidrug-resistant bacterial pathogens is essential to restrict the use of antibiotics. Bacteriophages (phages) constitute a major resource that can be harnessed as an alt... Read More about Bacteriophage ZCSE2 is a Potent Antimicrobial against Salmonella enterica Serovars: Ultrastructure, genomics and efficacy.