Engulfment, persistance and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential

Raghunathan, Dhaarini; Radford, Paul M.; Gell, Christopher; Negus, David; Moore, Christopher; Till, Rob; Tighe, Patrick J.; Wheatley, Sally P.; Martinez-Pomares, Luisa; Elizabeth Sockett, R.; Tyson, Jess

doi:10.1038/s41598-019-40223-3

All Outputs (5)

A cost-effective, analytical method for measuring metabolic load of mitochondria (2019)
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The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis (2019)
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The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cili... Read More about The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.

Transporting cells over several days without dry-ice (2019)
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This paper describes a simple, hazard-free and inexpensive procedure that allows researchers to send cultured cells across the globe at ambient temperatures. The method enables transit of up to 2?weeks without compromising cell recovery. Its use will... Read More about Transporting cells over several days without dry-ice.

Survivin at a glance (2019)
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Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all can... Read More about Survivin at a glance.

Engulfment, persistance and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential (2019)
Journal Article

In assessing the potential of predatory bacteria, such as Bdellovibrio bacteriovorus, to become live therapeutic agents against bacterial infections, it is crucial to understand and quantify Bdellovibrio host cell interactions at a molecular level. H... Read More about Engulfment, persistance and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential.