Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of haemophilus influenzae and its role in bacterial resistance to complement-mediated killing

Griffin, R.; Cox, Andrew D.; Makepeace, Katherine; Richards, J.C.; Moxon, E. Richard; Hood, Derek W.

doi:10.1128/IAI.73.4.2213-2221.2005

All Outputs (3)

p-Hydroxybenzoic acid synthesis in mycobacterium tuberculosis (2005)
Journal Article

Glycosylated p-hydroxybenzoic acid methyl esters and structurally related phenolphthiocerol glycolipids are important virulence factors of Mycobacterium tuberculosis. Although both types of molecules are thought to be derived from p-hydroxybenzoic ac... Read More about p-Hydroxybenzoic acid synthesis in mycobacterium tuberculosis.

Digalactoside expression in the lipopolysaccharide of haemophilus influenzae and its role in intravascular survival (2005)
Journal Article

Digalactoside (gal-1-4 gal) structures of the lipopolysaccharide (LPS) of Haemophilus influenzae are implicated in virulence. A confounding factor is that tetranucleotide repeats within the lic2A, lgtC, and lex2 genes mediate phase-variable expressio... Read More about Digalactoside expression in the lipopolysaccharide of haemophilus influenzae and its role in intravascular survival.

Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of haemophilus influenzae and its role in bacterial resistance to complement-mediated killing (2005)
Journal Article

The phase-variable locus lex2 is required for expression of a Haemophilus influenzae lipopolysaccharide (LPS) epitope of previously unknown structure. This epitope, which is reactive with monoclonal antibody (MAb) 5G8, has been associated with virule... Read More about Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of haemophilus influenzae and its role in bacterial resistance to complement-mediated killing.